Cloning, expression, crystallization and initial crystallographic analysis of the C-terminal domain of the amyloid precursor protein APP

2004 ◽  
Vol 60 (9) ◽  
pp. 1614-1617 ◽  
Author(s):  
Cora Keil ◽  
Robert Huber ◽  
Wolfram Bode ◽  
Manuel E. Than
Keyword(s):  
Amyloid Precursor Protein ◽  
Crystallographic Analysis ◽  
Precursor Protein ◽  
Terminal Domain

scholarly journals Structural Studies of the Transmembrane C-Terminal Domain of the Amyloid Precursor Protein (APP): Does APP Function as a Cholesterol Sensor?†‡

Biochemistry ◽  
2008 ◽  
Vol 47 (36) ◽  
pp. 9428-9446 ◽  
Author(s):  
Andrew J. Beel ◽  
Charles K. Mobley ◽  
Hak Jun Kim ◽  
Fang Tian ◽  
Arina Hadziselimovic ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Structural Studies ◽  
Terminal Domain

scholarly journals The Amyloid Precursor Protein C-Terminal Domain Alters CA1 Neuron Firing, Modifying Hippocampus Oscillations and Impairing Spatial Memory Encoding

Cell Reports ◽  
2019 ◽  
Vol 29 (2) ◽  
pp. 317-331.e5 ◽  
Author(s):  
Paula A. Pousinha ◽  
Xavier Mouska ◽  
Daniela Bianchi ◽  
Mariana Temido-Ferreira ◽  
Joana Rajão-Saraiva ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Amyloid Precursor Protein ◽  
Protein C ◽  
Precursor Protein ◽  
Memory Encoding ◽  
Neuron Firing ◽  
Terminal Domain

scholarly journals Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

2010 ◽  
Vol 285 (49) ◽  
pp. 38042-38052 ◽  
Author(s):  
Ping Gong ◽  
Kulandaivelu S. Vetrivel ◽  
Phuong D. Nguyen ◽  
Xavier Meckler ◽  
Haipeng Cheng ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Mutation Analysis ◽  
Broad Spectrum ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Terminal Domain ◽  
Secretase Activity
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