Implantable optical sensor for continuous monitoring of various hemoglobin derivatives and tissue perfusion

Author(s):  
Jens Fiala ◽  
Robert Gehrke ◽  
Niklas Weber ◽  
Philipp Bingger ◽  
Hans Zappe ◽  
...  
Sensors ◽  
2016 ◽  
Vol 16 (2) ◽  
pp. 224 ◽  
Author(s):  
Rabih Maamary ◽  
Xiaojuan Cui ◽  
Eric Fertein ◽  
Patrick Augustin ◽  
Marc Fourmentin ◽  
...  

2019 ◽  
Vol 25 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Chong Huang ◽  
Yutong Gu ◽  
Jing Chen ◽  
Ahmed A. Bahrani ◽  
Elie G. Abu Jawdeh ◽  
...  

1988 ◽  
Author(s):  
Masahiko Kanda ◽  
Kunihiko Taniguchi ◽  
Kunio Awazu ◽  
Yoshitaka Ishigami ◽  
Manabu Masuzawa ◽  
...  

2022 ◽  
Author(s):  
Ghassan Maan Salim ◽  
Mohd Anwar Zawawi

Abstract Knee joint is an important part of human body. People with poor knee condition generally have limited physical movement, rendering to mental stress and agony. Knee pain can be categorized into three groups, known as acute injury, chronic injury and medical condition. Current technology to support the knee diagnosis and treatment procedures are limited to the use of manual goniometer, x-ray and magnetic resonance imaging (MRI). Alternative devices with continuous measurement capability for knee monitoring are minimum at this time, mainly due to the difficulties to cover the wide angle of the knee flexion. X-ray and MRI technologies are useful to have some insight on the knee problem, but they are not applicable for continuous monitoring. Aside from being expensive for general use of MRI, x-ray on the other hand can cause short-term side effects due to radiation exposure. The aim of this paper is to demonstrate the use of optical sensor integrated with mechanical gear system as a knee monitoring device. A plastic compartment, made by using 3D printer is used to place the sensor and the gear system. The design of the overall device allows direct attachment on a knee brace for easy placement on the knee. Based on current study, the proposed sensor has a range of motion between 0 deg. to 160 deg., 0.08 deg. resolution as well as support continuous monitoring of the knee. The sensor performance has been demonstrated for gait motion, ascending and descending stairs, sit-to-stand movement and maximum knee flexion applications.


VASA ◽  
2017 ◽  
Vol 46 (5) ◽  
pp. 383-388 ◽  
Author(s):  
Henrik Christian Rieß ◽  
Anna Duprée ◽  
Christian-Alexander Behrendt ◽  
Tilo Kölbel ◽  
Eike Sebastian Debus ◽  
...  

Abstract. Background: Perioperative evaluation in peripheral artery disease (PAD) by common vascular diagnostic tools is limited by open wounds, medial calcinosis or an altered collateral supply of the foot. Indocyanine green fluorescent imaging (ICG-FI) has recently been introduced as an alternative tool, but so far a standardized quantitative assessment of tissue perfusion in vascular surgery has not been performed for this purpose. The aim of this feasibility study was to investigate a new software for quantitative assessment of tissue perfusion in patients with PAD using indocyanine green fluorescent imaging (ICG-FI) before and after peripheral bypass grafting. Patients and methods: Indocyanine green fluorescent imaging was performed in seven patients using the SPY Elite system before and after peripheral bypass grafting for PAD (Rutherford III-VI). Visual and quantitative evaluation of tissue perfusion was assessed in an area of low perfusion (ALP) and high perfusion (AHP), each by three independent investigators. Data assessment was performed offline using a specially customized software package (Institute for Laser Technology, University Ulm, GmbH). Slope of fluorescent intensity (SFI) was measured as time-intensity curves. Values were compared to ankle-brachial index (ABI), slope of oscillation (SOO), and time to peak (TTP) obtained from photoplethysmography (PPG). Results: All measurements before and after surgery were successfully performed, showing that ABI, TTP, and SOO increased significantly compared to preoperative values, all being statistically significant (P < 0.05), except for TTP (p = 0.061). Further, SFI increased significantly in both ALP and AHP (P < 0.05) and correlated considerably with ABI, TTP, and SOO (P < 0.05). Conclusions: In addition to ABI and slope of oscillation (SOO), the ICG-FI technique allows visual assessment in combination with quantitative assessment of tissue perfusion in patients with PAD. Ratios related to different perfusion patterns and SFI seem to be useful tools to reduce factors disturbing ICG-FI measurements.


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