Energetics and Hemodynamic Changes of Normal and Various Right Heart Bypass (Fontan) Circulations in Lambs under Varying Respiration Parameters

Author(s):  
M.E. Ketner ◽  
C.L. Lucas ◽  
M.R. Mill ◽  
B. Sheridan ◽  
W. Lucas
1992 ◽  
Vol 21 (5) ◽  
pp. 510-514
Author(s):  
Hajime OHZEKI ◽  
Satosi NAKAZAWA ◽  
Akira SAITO ◽  
Hisanaga MORO ◽  
Hirofumi OKAZAKI ◽  
...  

1978 ◽  
Vol 234 (2) ◽  
pp. H163-H166 ◽  
Author(s):  
H. K. Nakazawa ◽  
D. L. Roberts ◽  
F. J. Klocke

The fractions of left anterior descending (LAD) and circumflex (LC) inflow drainage into the canine great cardiac vein (GCV) and coronary sinus (CS) have been quantitated by use of a right heart bypass preparation in which GCV outflow was isolated from the remainder of CS outflow. Following direct LAD injection of indocyanine green dye (ICG), 63 +/- 8% (SD) of the total amount of dye recovered appeared in GCV outflow and the remainder in CS outflow. CS recovery of ICG was decreased appreciably by ligation of epicardial venous connections between the LAD and LC beds, but was not affected by selective reductions of LAD or LC inflow. Only 3 +/- 3% of ICG injected into the LC was recovered in GVC outflow under basal conditions, and these low values were not affected measurably by selective reductions of LAD or LC inflow. CS drainage of LAD inflow could be augmented by selective increments of GCV pressure exceeding 7-10 mmHg. Increments of LC drainage in GCV outflow required CS pressures that exceeded GCV pressures by greater than 10 mmHg.


2020 ◽  
Vol 11 (2) ◽  
pp. 198-203
Author(s):  
Giovanni Stellin

Cavopulmonary anastomosis was first described by Carlon, Mondini, De Marchi in a canine model in 1951 and later, in the clinical practice, by Glenn in 1958. Total right heart bypass was first introduced by Fontan and Kreutzer in 1971, in each instance as treatment for tricuspid atresia. Several modifications of such a procedure followed the initial concept of the right atrium as a pumping chamber, including modifications aimed to minimize energy loss at the anastomotic level and arrhythmias. Tribute is given to our pioneers who developed such an operation aimed to treat any child with functionally univentricular hearts.


2006 ◽  
Vol 40 (4) ◽  
pp. 341-352 ◽  
Author(s):  
S Schauvliege ◽  
K Narine ◽  
S Bouchez ◽  
D Desmet ◽  
V Van Parys ◽  
...  

1965 ◽  
Vol 20 (5) ◽  
pp. 816-824 ◽  
Author(s):  
J. M. Workman ◽  
R. W. B. Penman ◽  
B. Bromberger-Barnea ◽  
S. Permutt ◽  
R. L. Riley

The effect of transpulmonary pressure (Ptp) on gas exchange in the dog lung was studied in 10 open-chested dogs. Rates of pulmonary perfusion and ventilation were held constant (right heart bypass and pump respirator) while Ptp was varied. Alveolar dead space ventilation and alveolar shunt perfusion were calculated from CO2 and O2 gradients. The results are finally expressed in terms of a three-compartment lung model. It is shown that a misinterpretation is possible if alveolar dead space or alveolar shunt compartments are expressed as fractions, respectively, of all ventilated or all perfused alveoli, therefore each has been expressed as a fraction of the whole lung. It is concluded that the alveolar shunt compartment decreased as Ptp was increased, over the lower range of Ptp studied. No significant change was detected in the alveolar dead space compartment, as Ptp was varied. alveolar-arterial O2 gradient; anatomical dead space; arterial-alveolar CO2 gradient; distribution of pulmonary perfusion; distribution of pulmonary ventilation; right heart bypass preparation; ventilation/perfusion relationships Submitted on February 16, 1965


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