Impact of tracer distribution, count level, iterations and post-smoothing on PET quantification using a variously weighted least squares algorithm

Author(s):  
Etienne Letourneau ◽  
Jeroen Verhaeghe ◽  
Andrew J. Reader
2016 ◽  
Vol 28 (2) ◽  
pp. 206-218 ◽  
Author(s):  
Hong-qi Yang ◽  
Mu-guo Li ◽  
Shu-xue Liu ◽  
Fang-mei Chen

2003 ◽  
Vol 125 (3) ◽  
pp. 624-633 ◽  
Author(s):  
D. L. Doel

Gas turbine performance analysis programs convert raw measurements (thrust, fuel flow, gas path temperatures, and pressures) into engine and component figures of merit (e.g., specific fuel consumption, component efficiencies). The derived parameters allow a diagnostician to recognize a poorly performing engine and help to identify the root cause for the problem. These goals can be foiled by measurement problems or by analysis assumptions embedded in the programs. A gifted analyst learns to recognize measurement or assumption problems via characteristic “fingerprints” in the program output. The latest data analysis tools tackle the same issues using a weighted-least-squares algorithm which estimates sensor errors at the same time component health is being determined. The weighted-least-squares algorithm modifies the “fingerprint” of a measurement problem and also that of a problem-free solution. To develop intuition for these new programs, the analyst must understand how weighted-least-squares works and how normal and problem situations are reflected in the output. This paper describes the weighted-least-squares algorithm, as implemented in GE’s TEMPER program, with the goal of stimulating a new intuition for interpreting gas path analysis results.


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