scholarly journals Circulating IgA Anti-Basement Membrane Zone Antibodies in Dermatitis Herpetiformis

1977 ◽  
Vol 69 (6) ◽  
pp. 558-560 ◽  
Author(s):  
Hideo. Yaoita ◽  
Stephen I Katz
Keyword(s):  
Basement Membrane ◽  
Dermatitis Herpetiformis ◽  
Basement Membrane Zone

Bullous disorders

2018 ◽  
Author(s):  
Emily Davies
Keyword(s):  
Basement Membrane ◽  
Dermatitis Herpetiformis ◽  
Pemphigus Vulgaris ◽  
Basement Membrane Zone ◽  
Mucous Membrane Pemphigoid ◽  
Pemphigus Foliaceus ◽  
Pemphigoid Gestationis ◽  
Bullous Disease ◽  
Adhesion Junctions ◽  
Linear Iga Disease

This chapter focuses on immunobullous diseases. The immunobullous disorders are a group of diseases in which pathogenic autoantibodies bind to target antigens either in desmosomes (intra-epidermal intracellular adhesion junctions) or in part of the basement membrane zone, resulting in loss of adhesion, and blister formation. This chapter will focus on pemphigus vulgaris, pemphigus foliaceus, bullous pemphigoid, linear IgA disease, chronic bullous disease of childhood, and dermatitis herpetiformis; it will also mention mucous membrane pemphigoid, pemphigoid gestationis, and epidermolysis bullosa acquisita.

Vesiculobullous disease

2010 ◽  
pp. 4602-4609
Author(s):  
Fenella Wojnarowska
Keyword(s):  
Basement Membrane ◽  
Clinical Presentation ◽  
Dermatitis Herpetiformis ◽  
Basement Membrane Zone ◽  
Genetic Mutations ◽  
Bullous Diseases ◽  
Pathogenic Antibodies ◽  
Adhesion Complex ◽  
Substantial Morbidity ◽  
Autoimmune Blistering Diseases

The autoimmune blistering diseases have a dramatic clinical presentation, and are significant diseases with substantial morbidity and mortality. The diseases can be split broadly pathologically into intraepidermal (pemphigus) and subepidermal (pemphigoid, dermatitis herpetiformis and others) groups, the former being characterized by pathogenic autoantibodies to desmosome components, and the latter by pathogenic antibodies to proteins of the basement membrane zone adhesion complex that link the epithelium/epidermis to the underlying mesenchyme/dermis (or genetic mutations of the same proteins). There are concomitant differences in clinical presentation, e.g. blistering lesions present in the subepidermal bullous diseases tend to be less easily ruptured than those observed in intraepidermal bullous diseases....

scholarly journals IgA Antibodies in Chronic Bullous Disease of Childhood React with a 97kDa Basement Membrane Zone Protein

1996 ◽  
Vol 106 (6) ◽  
pp. 1277-1280 ◽  
Author(s):  
John J. Zone ◽  
Ted B. Taylor ◽  
Donald P. Kadunce ◽  
Tadeusz P. Chorzelski ◽  
Lawrence A. Schachner ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Basement Membrane Zone ◽  
Bullous Disease ◽  
Iga Antibodies
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