scholarly journals Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: The OPuS-2 study

Allergy ◽  
2018 ◽  
Vol 73 (9) ◽  
pp. 1871-1880 ◽  
Author(s):  
M. A. Riedl ◽  
E. Aygören-Pürsün ◽  
J. Baker ◽  
H. Farkas ◽  
J. Anderson ◽  
...  
Keyword(s):  
Hereditary Angioedema ◽  
Phase 3 ◽  
Kallikrein Inhibitor

Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)

2021 ◽  
Vol 64 (17) ◽  
pp. 12453-12468
Author(s):  
Pravin L Kotian ◽  
Minwan Wu ◽  
Satish Vadlakonda ◽  
Venkat Chintareddy ◽  
Pengcheng Lu ◽  
...  
Keyword(s):  
Hereditary Angioedema ◽  
Plasma Kallikrein ◽  
Kallikrein Inhibitor

A review of kallikrein inhibitor lanadelumab in hereditary angioedema

Immunotherapy ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 937-944 ◽  
Author(s):  
Gloria Hwang ◽  
Ansh Johri ◽  
Sally Ng ◽  
Timothy Craig
Keyword(s):  
Hereditary Angioedema ◽  
Kallikrein Inhibitor

scholarly journals Oral berotralstat for the prophylaxis of hereditary angioedema attacks in patients in Japan: A phase 3 randomized trial

Allergy ◽  
2020 ◽  
Author(s):  
Isao Ohsawa ◽  
Daisuke Honda ◽  
Yusuke Suzuki ◽  
Tomoo Fukuda ◽  
Keisuke Kohga ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Hereditary Angioedema ◽  
Phase 3

OR034 Lanadelumab for prevention of attacks in hereditary angioedema: results from the phase 3 HELP study

2017 ◽  
Vol 119 (5) ◽  
pp. S5 ◽  
Author(s):  
A. Banerji ◽  
M. Riedl ◽  
J. Bernstein ◽  
M. Cicardi ◽  
H. Longhurst ◽  
...  
Keyword(s):  
Hereditary Angioedema ◽  
Phase 3

scholarly journals Subgroup Analyses From the Phase 3 HELP Study of Lanadelumab for the Prevention of Hereditary Angioedema Attacks

2019 ◽  
Vol 143 (2) ◽  
pp. AB42 ◽  
Author(s):  
Aleena Banerji ◽  
Michael E. Manning ◽  
Inmaculada Martinez-Saguer ◽  
Lawrence B. Schwartz ◽  
Andrew M. Smith ◽  
...  
Keyword(s):  
Hereditary Angioedema ◽  
Phase 3 ◽  
Subgroup Analyses
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