Distal intestinal obstruction syndrome in cystic fibrosis: presentation, outcome and management in a tertiary hospital (2007-2012)

2013 ◽  
Vol 84 (10) ◽  
pp. 740-744 ◽  
Author(s):  
Rami Subhi ◽  
Rachel Ooi ◽  
Felicity Finlayson ◽  
Tom Kotsimbos ◽  
John Wilson ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Tertiary Hospital ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

scholarly journals Distal intestinal obstruction syndrome: a diagnostic and therapeutic challenge in cystic fibrosis

2020 ◽  
Vol 96 (6) ◽  
pp. 732-740 ◽  
Author(s):  
Natascha S. Sandy ◽  
Lilian H.P. Massabki ◽  
Aline C. Gonçalves ◽  
Antonio F. Ribeiro ◽  
Jose D. Ribeiro ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Therapeutic Challenge ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

Distal Intestinal Obstruction Syndrome resolved by dissolution with Coca-Cola® via colonoscopy in a cystic fibrosis patient

2020 ◽  
Vol 19 (6) ◽  
pp. e43-e44
Author(s):  
Carlos Ferre-Aracil ◽  
Mariano González-Haba ◽  
Beatriz Tormo-Lanseros ◽  
Luis Giménez-Alvira ◽  
Manuel Jiménez-Garrido
Keyword(s):  
Cystic Fibrosis ◽  
Intestinal Obstruction ◽  
Cystic Fibrosis Patient ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

Lavage Treatment of Distal Intestinal Obstruction Syndrome in Children With Cystic Fibrosis

PEDIATRICS ◽  
1989 ◽  
Vol 83 (5) ◽  
pp. 727-733
Author(s):  
Sibylle Koletzko ◽  
David A. Stringer ◽  
Geoffrey J. Cleghorn ◽  
Peter R. Durie
Keyword(s):  
Cystic Fibrosis ◽  
Abdominal Pain ◽  
Intestinal Obstruction ◽  
Nasogastric Tube ◽  
Adverse Reactions ◽  
Iliac Fossa ◽  
Medical Attention ◽  
Patient Reported ◽  
Distal Intestinal Obstruction Syndrome ◽  
Distal Intestinal Obstruction

The efficacy, adverse reactions, and long-term effects of intestinal lavage treatment with a balanced electrolyte solution (Golytely) was evaluated in patients with cystic fibrosis and distal intestinal obstruction syndrome. Twenty-two patients with cystic fibrosis (mean age 21.8 years, range 14 to 34 years, 15 boys or men) who sought medical attention because of abdominal pain and a mass in the right iliac fossa received Golytely, 5.6 ± 1.9 L (mean ± 1 SD), either orally (n = 14) or via nasogastric tube (n = 8) during 5.6 ± 2.4 hours. No serious side effects occurred. Serum electrolyte values remained within normal limits. Body weight did not change significantly. Minor adverse reactions included bloating (n = 12), nausea (n = 8), vomiting (n = 1), and chills (n = 3). All but one patient reported impressive relief of symptoms and remained pain free for an average of 3 months (range 1 to 19 months). Symptoms of abdominal pain and radiologic signs of fecal impaction assessed before and after lavage both decreased significantly (P < .0001). During follow-up (mean 15.2 months, range 4 to 26 months), 11 patients required a total of 38 (range one to nine) additional doses of Golytely. Seven patients drank the solution at home (21 treatments); only two patients chose a nasogastric tube. In ten patients with symptoms of recurrent distal intestinal obstruction syndrome prior to institution of therapy, duration of hospitalization was significantly reduced by this treatment (5.1 ± 7.6 v 2.3 ± 6.3 hospital days per annum, P < .02). It is concluded that intestinal lavage is a well-accepted, safe, and effective therapy for distal intestinal obstruction syndrome in patients with cystic fibrosis.

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