scholarly journals Non-invasive algorithm of enhanced liver fibrosis and liver stiffness measurement with transient elastography for advanced liver fibrosis in chronic hepatitis B

2013 ◽  
Vol 39 (2) ◽  
pp. 197-208 ◽  
Author(s):  
G. L.-H. Wong ◽  
H. L.-Y. Chan ◽  
P. C.-L. Choi ◽  
A. W.-H. Chan ◽  
Z. Yu ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Transient Elastography ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Non Invasive ◽  
Advanced Liver Fibrosis

Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B

2009 ◽  
Vol 16 (1) ◽  
pp. 36-44 ◽  
Author(s):  
H. L.-Y. Chan ◽  
G. L.-H. Wong ◽  
P. C.-L. Choi ◽  
A. W.-H. Chan ◽  
A. M.-L. Chim ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Alanine Aminotransferase ◽  
Transient Elastography ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement

scholarly journals Development of a non-invasive algorithm with transient elastography (Fibroscan) and serum test formula for advanced liver fibrosis in chronic hepatitis B

2010 ◽  
Vol 31 (10) ◽  
pp. 1095-1103 ◽  
Author(s):  
G. L. H. WONG ◽  
V. W. S. WONG ◽  
P. C. L. CHOI ◽  
A. W. H. CHAN ◽  
H. L. Y. CHAN
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Transient Elastography ◽  
Non Invasive ◽  
Serum Test ◽  
Advanced Liver Fibrosis

A diagnostic algorithm for assessment of liver fibrosis by liver stiffness measurement in patients with chronic hepatitis B

2017 ◽  
Vol 24 (11) ◽  
pp. 1005-1015 ◽  
Author(s):  
Y.-J. Cai ◽  
J.-J. Dong ◽  
X.-D. Wang ◽  
S.-S. Huang ◽  
R.-C. Chen ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Liver Stiffness ◽  
Diagnostic Algorithm ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement

Increased liver stiffness measurement by transient elastography in severe acute exacerbation of chronic hepatitis B

2009 ◽  
Vol 24 (6) ◽  
pp. 1002-1007 ◽  
Author(s):  
Grace L-H Wong ◽  
Vincent W-S Wong ◽  
Paul C-L Choi ◽  
Anthony W-H Chan ◽  
Angel M-L Chim ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Acute Exacerbation ◽  
Chronic Hepatitis B ◽  
Transient Elastography ◽  
Liver Stiffness ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Severe Acute Exacerbation

Role of serum M2BPGi levels in diagnosing significant liver fibrosis and cirrhosis in patients with chronic hepatitis B

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Marcel William Keddeas ◽  
Hany Haroun Kaisar ◽  
Hagar Ahmed Ahmed Elessawy ◽  
Mariam Samir Abdel Hamid Elewa
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Serum Level ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Transient Elastography ◽  
Liver Stiffness ◽  
Protein Glycosylation ◽  
Control Group ◽  
Serum Samples

Abstract Background and aim Mac-2-binding protein glycosylation isomer (M2BPGi) is a novel serum diagnostic marker for liver fibrosis in various liver diseases. We aimed to evaluate its role in assessment of liver fibrosis in chronic hepatitis B infection (CHB) with reference to liver stiffness measurement (LSM) by transient elastography (Fibroscan). Design and Methods A case control study. 50 CHB patients with LSM by transient elastography technology and retrievable serum samples and 20 normal volunteers as a control group were recruited. Results 50 CHB patients (M: F = 30:20; mean age 43years ± 10.58) and 20 normal control volunteers (M: F = 12:8; mean age 37years ± 14.5) were recruited. The mean M2BPGi values for control group, F0-F1, F2, F3 and F4 progressively increased with more advanced stages of liver fibrosis: 0.282, 0.719, 1.322, 1.65 and 1.904 COI, respectively (p < 0.001). M2BPGi levels correlated well with liver stiffness (r = 0.911) and moderately with FIB-4 (r = 0.682), and with APRI (r = 0.536) (all p < 0.001). Using cut-off values of 0.455, 1.02, 1.16, 1.66 and 1.71COI for control, F0-F1, F2, F3 and F4 groups, respectively, the AUROCs were 0.996, 0.996, 0.691, 0.794 and 1.00 for control, F0-F1, F2, F3 and F4 groups, respectively. There was a statistically significant but with weak positive correlation between M2BPGi serum level and INR (r = 0.333, p = 0.018). And there was a statistically significant but with weak negative correlation between M2BPGi serum level and platelet count (r = -0.41, p = 0.003) and HBV DNA (r = -0.373, p = 0.008).There was a statistically significance between M2BPGi serum level and the history of varices (p = 0.023) Conclusions WFA+-M2BP is an accurate serum indicator for assessing different stages of liver fibrosis. WFA+-M2BP provides a simple and reliable alternative or complementary method to liver biopsy and FibroScan.

scholarly journals Controlled attenuation parameter value-based diagnostic algorithm improves the accuracy of liver stiffness measurement in chronic hepatitis B patients

Aging ◽  
2020 ◽  
Vol 12 (16) ◽  
pp. 16072-16082
Author(s):  
Yaoxin Fan ◽  
Lin Wang ◽  
Yang Ding ◽  
Qiuju Sheng ◽  
Chong Zhang ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Liver Stiffness ◽  
Diagnostic Algorithm ◽  
Controlled Attenuation Parameter ◽  
Liver Stiffness Measurement ◽  
Stiffness Measurement ◽  
Attenuation Parameter
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