Vancomycin immediate skin responses in vancomycin‐naïve subjects

2021 ◽  
Author(s):  
Santiago Alvarez‐Arango ◽  
Eric Oliver ◽  
Olive Tang ◽  
Trisha Saha ◽  
Corinne A. Keet ◽  
...  
Keyword(s):  
Skin Responses

scholarly journals A molecularly defined skin test reagent for the diagnosis of bovine tuberculosis compatible with vaccination against Johne’s Disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sonya Middleton ◽  
Sabine Steinbach ◽  
Michael Coad ◽  
Kevina McGill ◽  
Colm Brady ◽  
...  
Keyword(s):  
Skin Test ◽  
Recombinant Proteins ◽  
Bovine Tuberculosis ◽  
Synthetic Peptides ◽  
Blood Test ◽  
High Specificity ◽  
Active Components ◽  
Interferon Gamma Release Assays ◽  
Skin Responses

AbstractTuberculin Purified Protein Derivatives (PPDs) exhibit multiple limitations: they are crude extracts from mycobacterial cultures with largely unknown active components; their production depends on culture of mycobacteria requiring expensive BCL3 production facilities; and their potency depends on the technically demanding guinea pig assay. To overcome these limitations, we developed a molecularly defined tuberculin (MDT) by adding further antigens to our prototype reagent composed of ESAT-6, CFP-10 and Rv3615c (DIVA skin test, DST). In vitro screening using PBMC from infected and uninfected cattle shortlisted four antigens from a literature-based list of 18 to formulate the MDT. These four antigens plus the previously identified Rv3020c protein, produced as recombinant proteins or overlapping synthetic peptides, were formulated together with the three DST antigens into the MDT to test cattle experimentally and naturally infected with M. bovis, uninfected cattle and MAP vaccinated calves. We demonstrated significant increases in MDT-induced skin responses compared to DST in infected animals, whilst maintaining high specificity in unvaccinated or MAP vaccinated calves. Further, MDT can also be applied in in vitro blood-based interferon-gamma release assays. Thus, MDT promises to be a robust diagnostic skin and blood test reagent overcoming some of the limitations of PPDs and warrants full validation.

The effects of alternate-day corticosteroid therapy on delayed hypersensitivity skin responses

1976 ◽  
Vol 6 (5) ◽  
pp. 507-514 ◽  
Author(s):  
DAVID G. TINKELMAN ◽  
MICHAEL Z. BLUMBERG
Keyword(s):  
Corticosteroid Therapy ◽  
Delayed Hypersensitivity ◽  
Hypersensitivity Skin ◽  
Skin Responses

Habituation patterns of fMRI BOLD and sympathetic skin responses to painful laser stimulation

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S62
Author(s):  
A Mobascher ◽  
J Brinkmeyer ◽  
T Warbrick ◽  
F Musso ◽  
HJ Wittsack ◽  
...  
Keyword(s):  
Laser Stimulation ◽  
Skin Responses ◽  
Sympathetic Skin Responses

Skin Responses to Ultraviolet Radiation: Effects of Constitutive Pigmentation, Sex, and Ancestry

2002 ◽  
Vol 15 (5) ◽  
pp. 385-390 ◽  
Author(s):  
Jennifer K. Wagner ◽  
Esteban J. Parra ◽  
Heather L. Norton ◽  
Celina Jovel ◽  
Mark D. Shriver
Keyword(s):  
Ultraviolet Radiation ◽  
Radiation Effects ◽  
Skin Responses

Grass pollen injection immunotherapy: Time course of suppression of allergen-induced late-phase skin responses

2005 ◽  
Vol 115 (2) ◽  
pp. S266 ◽  
Author(s):  
G. Paraskevopoulos ◽  
M.R. Jacobson ◽  
V. Carr ◽  
M. Calderon ◽  
S.J. Till ◽  
...  
Keyword(s):  
Grass Pollen ◽  
Time Course ◽  
Late Phase ◽  
Skin Responses

Sympathetic sudomotor skin responses induced by laser stimuli in normal human subjects

2002 ◽  
Vol 334 (2) ◽  
pp. 115-118 ◽  
Author(s):  
Alvaro Cervera ◽  
Misericordia Veciana ◽  
Josep Valls-Solé
Keyword(s):  
Human Subjects ◽  
Normal Human ◽  
Skin Responses

Sympathetic skin responses evoked by magnetic stimulation of the neck

1995 ◽  
Vol 128 (2) ◽  
pp. 188-194 ◽  
Author(s):  
Kaoru Matsunaga ◽  
Takenori Uozumi ◽  
Sadatoshi Tsuji ◽  
Yoshiyuki Murai
Keyword(s):  
Magnetic Stimulation ◽  
Skin Responses ◽  
Sympathetic Skin Responses ◽  
Stimulation Of

scholarly journals Digestibility, blood levels of nutrients and skin responses of calves fed soyabean and lupin proteins

1995 ◽  
Vol 35 (1) ◽  
pp. 27-44 ◽  
Author(s):  
HM Tukur ◽  
P. Branco Pardal ◽  
M. Formal ◽  
R. Toullec ◽  
JP Lallès ◽  
...  
Keyword(s):  
Blood Levels ◽  
Skin Responses

Rapid Effects of Olopatadine Hydrochloride on the Histamine-Induced Skin Responses

2002 ◽  
Vol 29 (11) ◽  
pp. 709-712 ◽  
Author(s):  
Keisuke Morita ◽  
Tetsuya Koga ◽  
Yoichi Moroi ◽  
Kazunori Urabe ◽  
Masutaka Furue
Keyword(s):  
Skin Responses ◽  
Olopatadine Hydrochloride
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