Cutaneous adverse drug reaction after apomorphine infusion, possibly caused by a systemic type IV hypersensitivity reaction to sodium metabisulfite: Report of 2 cases

2018 ◽  
Vol 79 (5) ◽  
pp. 316-318 ◽  
Author(s):  
Robbert W. K. Borgemeester ◽  
Teus van Laar ◽  
Marie L. A. Schuttelaar
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Hypersensitivity Reaction ◽  
Sodium Metabisulfite ◽  
Type Iv ◽  
Cutaneous Adverse Drug Reaction

Successful desensitization of a patient with cetuximab hypersensitivity: A case report

2018 ◽  
Vol 25 (7) ◽  
pp. 1726-1730 ◽  
Author(s):  
Mohammad Solduzian ◽  
Saeed Anvari ◽  
Hamidreza Taghvaye Masoumi ◽  
Farhad Shahi ◽  
Zahra Jahangard-Rafsanjani
Keyword(s):  
Colorectal Cancer ◽  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Hypersensitivity Reaction ◽  
Drug Discontinuation ◽  
Hypersensitivity Reactions ◽  
Case Description ◽  
Treatment Team ◽  
Desensitization Protocol ◽  
Severe Hypersensitivity Reaction

Background Severe hypersensitivity reaction is a dangerous adverse drug reaction in patients receiving cetuximab. It requires drug discontinuation and medical management. Case description A 48-year-old man, previously diagnosed with metastatic colorectal cancer, was admitted for therapy continuation. During the first infusion of cetuximab, the patient experienced acute signs of hypersensitivity reactions. The treatment team decided to administer cetuximab employing the desensitization protocol. Conclusions This study reports a severe hypersensitivity reaction to cetuximab in an adult patient with colorectal cancer. This patient was successfully managed with a new safe and rapid desensitization protocol.

Clinical application of static fluorescence-based cytometry, Cellscan, in cutaneous adverse drug reaction

2010 ◽  
Vol 38 (5) ◽  
pp. 447-455
Author(s):  
Fares SALAMEH ◽  
Martine Szyper KRAVITZ ◽  
Aviv BARZILAI ◽  
Sharon BAUM ◽  
Yehuda SHOENFELD ◽  
...  
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Clinical Application ◽  
Cutaneous Adverse Drug Reaction

Severe Cutaneous Adverse Drug Reaction to Leflunomide: A Report of Two Cases

2008 ◽  
Vol 27 (1) ◽  
pp. 5-9 ◽  
Author(s):  
Xingdong Jian ◽  
Guangran Guo ◽  
Yanjun Ruan ◽  
Dawei Lin ◽  
Xingfu Li
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Cutaneous Adverse Drug Reaction
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