Clinical study designs and corresponding levels of evidence: time to redefine?

2015 ◽  
Vol 17 (9) ◽  
pp. 745-746 ◽  
Author(s):  
Christianne Buskens
2012 ◽  
Vol 18 (3) ◽  
pp. 50
Author(s):  
Maria G. Tanzi
Keyword(s):  

Neurosurgery ◽  
2019 ◽  
Vol 86 (1) ◽  
pp. 14-18
Author(s):  
Christopher E Louie ◽  
Erin D’Agostino ◽  
Alexander Woods ◽  
Timothy Ryken

Abstract There is inadequate neurosurgical literature discussing appropriate clinical study design. Here, we explore considerations for 2 fundamental study designs of epidemiology: experimental and observational cohort studies, through examples of theoretical yet realistic neurosurgical research questions. By examining 2 common neurosurgical procedures—namely, subdural drains for evacuation of chronic subdural hematoma, and the utility of navigation for placing external ventricular drains—we characterize the framework of cohort study models for clinical research applications.


2018 ◽  
Vol 32 (6) ◽  
pp. 2789-2801 ◽  
Author(s):  
Aalok K. Kacha ◽  
Sarah L. Nizamuddin ◽  
Junaid Nizamuddin ◽  
Harish Ramakrishna ◽  
Sajid S. Shahul

1997 ◽  
Vol 31 (3) ◽  
pp. 655-663 ◽  
Author(s):  
Rafe M. J. Donahue ◽  
Stephen J. Ruberg

2018 ◽  
pp. 41-51
Author(s):  
Richard B. North ◽  
Jane Shipley
Keyword(s):  

Urology ◽  
2000 ◽  
Vol 55 (4) ◽  
pp. 468-476 ◽  
Author(s):  
Andrew L Rosenberg ◽  
John T Wei
Keyword(s):  

2010 ◽  
Vol 149 (3) ◽  
pp. 367-370 ◽  
Author(s):  
Jie Jin Wang ◽  
John Attia

2002 ◽  
Vol 3 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Karen J. Sherman ◽  
Lixing Lao ◽  
Hugh MacPherson ◽  
George Lewith ◽  
Val Hopwood ◽  
...  

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