Late leakage after anterior resection: a defunctioning stoma alters the clinical course of anastomotic leakage

2018 ◽  
Vol 20 (2) ◽  
pp. 150-159 ◽  
Author(s):  
H. Jutesten ◽  
J. Draus ◽  
J. Frey ◽  
G. Neovius ◽  
G. Lindmark ◽  
...  
Keyword(s):  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Clinical Course ◽  
Defunctioning Stoma

Defunctioning Stoma Reduces Symptomatic Anastomotic Leakage After Low Anterior Resection of the Rectum for Cancer: A Randomized Multicenter Trial

2008 ◽  
Vol 247 (4) ◽  
pp. 718-719 ◽  
Author(s):  
Alexander A.F.A. Veenhof ◽  
Donald L. van der Peet ◽  
Wilhelmus J.H.J. Meijerink ◽  
Miguel A. Cuesta
Keyword(s):  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Multicenter Trial ◽  
Defunctioning Stoma

Defunctioning Stoma Reduces Symptomatic Anastomotic Leakage After Low Anterior Resection of the Rectum for Cancer: A Randomized Multicenter Trial

2008 ◽  
Vol 247 (4) ◽  
pp. 719-720 ◽  
Author(s):  
Peter Matthiessen ◽  
Olof Hallböök ◽  
Jörgen Rutegård ◽  
Göran Simert ◽  
Rune Sjödahl
Keyword(s):  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Multicenter Trial ◽  
Defunctioning Stoma

scholarly journals Ultralow anterior resection with implantation of gentamicin-collagen sponge and no defunctioning stoma: anastomotic leakage and local cancer relapse

2019 ◽  
Vol 53 (1) ◽  
pp. 77-84 ◽  
Author(s):  
Tomasz Michalik ◽  
Rafał Matkowski ◽  
Przemyslaw Biecek ◽  
Jozef Forgacz ◽  
Bartlomiej Szynglarewicz
Keyword(s):  
Rectal Cancer ◽  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Local Relapse ◽  
Collagen Sponge ◽  
Safe Procedure ◽  
Defunctioning Stoma ◽  
Ultralow Anterior Resection ◽  
Increased Risk ◽  
Low Incidence

Abstract Background Anterior resection with total mesorectal excision (TME) of ultralow rectal cancer may result in the increased risk of the anastomotic leakage (AL). The aim of this study was to evaluate the usefulness of the gentamicin-collagen sponge (GCS) for the protection against symptomatic AL and investigate association between AL and local relapse (LR). Patients and methods A series of 158 patients with ultralow rectal cancer was studied. All the patients underwent R0 sphincter-saving TME with anastomosis wrapping using GCS. In none of the cases a temporary protective stoma was constructed. Results AL rate was 3.2% (5/158) while median time to AL diagnosis was 5 days following surgery (range 3-15). There was no postoperative and leakage-related mortality. Patient age > 75 years and smoking were independent risk factors related to significantly increased AL rate: 12.5% vs. 0.8% (P = 0.0004) and 5.7% vs. 0% P = 0.043), respectively. LR was observed in 12% of cases. It was highly significantly more common and developed earlier in patients who have had AL when compared with non-AL group: 80% vs. 9% (P = 0.00001) and 8.5 vs. 17 months (P = 0.014), respectively. Conclusions Anastomosis wrapping with GCS after anterior resection with TME is a safe procedure resulting in the low incidence of anastomotic leakage which may be also associated with decreased risk of local relapse.

scholarly journals Defunctioning Stoma Reduces Symptomatic Anastomotic Leakage After Low Anterior Resection of the Rectum for Cancer

2007 ◽  
Vol 246 (2) ◽  
pp. 207-214 ◽  
Author(s):  
Peter Matthiessen ◽  
Olof Hallb????k ◽  
J??rgen Ruteg??rd ◽  
G??ran Simert ◽  
Rune Sj??dahl
Keyword(s):  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Defunctioning Stoma

scholarly journals Surgical-related risk factors associated with anastomotic leakage after resection for rectal cancer: a meta-analysis

2019 ◽  
Vol 50 (1) ◽  
pp. 20-28
Author(s):  
Xiao-Tong Wang ◽  
Lei Li ◽  
Fan-Biao Kong ◽  
Xiao-Gang Zhong ◽  
Wei Mai
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Blood Transfusion ◽  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Meta Analysis ◽  
Random Effect ◽  
Operation Time ◽  
Defunctioning Stoma ◽  
Related Risk

Abstract Objectives Anastomotic leakage (AL) after anterior resection always leads to longer hospital stays, decreased quality of life and even increased mortality. Despite extensive research, no consensus on the world well-concerned surgical-related risk factors exists. We therefore conducted a meta-analysis of the available published literature to identify the effects of surgical-related risk factors for AL after anterior resection for rectal cancer, hoping to provide more information and improved guidance for clinical workers managing patients with rectal cancer who are at a high risk for AL. Methods In this study, the relevant articles were systematically searched from EMBASE, MEDLINE, PubMed, WangFang (Database of Chinese Ministry of Science & Technology), Chinese National Knowledge Infrastructure Database and China Biological Medicine Database. The pooled odds ratio (OR) with 95% confidence interval (95% CI) were calculated. Meta-analysis was performed using of RevMan 5.3 software. Results A total of 26 studies met the inclusion criteria and comprised 34238 cases. Analysis of these 26 studies showed that no defunctioning stoma was highly correlated with AL (pooled OR = 1.28, 95%CI: 1.05–1.57, P = 0.01, random effect), and intraoperative blood transfusion was significantly associated with AL (pooled OR = 1.64, 95%CI: 1.34–2.02, P = 0.02, random effect). However, the AL was not associated with type of anastomosis, type of surgery, technique of anastomosis, level of inferior mesenteric artery ligation, operation time and splenic flexure mobilization. Conclusions Depend on this meta-analysis, no defunctioning stoma and intraoperative blood transfusion are the major surgical-related risk factors for AL after resection for rectal cancer. Because of the inherent limitations of the research, future prospective randomized controlled trials will need to confirm this conclusion.

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