scholarly journals Balanced propofol sedation for endoscopic retrograde cholangiopancreatography and octogenarians: Can we achieve both safety and efficacy?

2017 ◽  
Vol 29 (3) ◽  
pp. 297-298 ◽  
Author(s):  
John Vargo
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy ◽  
Propofol Sedation ◽  
Balanced Propofol Sedation

Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography in Nonagenarians: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Umair Iqbal ◽  
Hafsa Anwar ◽  
Muhammad Ali Khan ◽  
Simcha Weissman ◽  
Shivangi T. Kothari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Meta Analysis ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy

ID: 3516964 SAFETY AND EFFICACY OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN NONAGENARIANS: IS 90 REALLY THE NEW 60? A SYSTEMATIC REVIEW AND META-ANALYSIS

2021 ◽  
Vol 93 (6) ◽  
pp. AB127
Author(s):  
Umair Iqbal ◽  
Hafsa Anwar ◽  
Muhammad Ali Khan ◽  
Simcha Weissman ◽  
Shivangi Kothari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Meta Analysis ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy

scholarly journals Doxapram as an additive to propofol sedation for endoscopic retrograde cholangiopancreatography: a placebo-controlled, randomized, double-blinded study

2020 ◽  
Vol 34 (12) ◽  
pp. 5477-5483 ◽  
Author(s):  
Jarno Jokelainen ◽  
Anna Belozerskikh ◽  
Harri Mustonen ◽  
Marianne Udd ◽  
Leena Kylänpää ◽  
...  
Keyword(s):  
Respiratory Depression ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Significant Rise ◽  
Repeated Measurements ◽  
Double Blind Study ◽  
Continuous Variables ◽  
Endoscopic Retrograde ◽  
Double Blind ◽  
Clinical Trial Registration ◽  
Propofol Sedation

Abstract Background Endoscopic retrograde cholangiopancreatography (ERCP) requires moderate to deep sedation, usually with propofol. Adverse effects of propofol sedation are relatively common, such as respiratory and cardiovascular depression. This study was conducted to determine if doxapram, a respiratory stimulant, could be used to reduce the incidence of respiratory depression. Methods This is a single-center, prospective randomized double-blind study performed in the endoscopy unit of Helsinki University Central Hospital. 56 patients were randomized in a 1:1 ratio to either receive doxapram as an initial 1 mg/kg bolus and an infusion of 1 mg/kg/h (group DOX) or placebo (group P) during propofol sedation for ERCP. Main outcome measures were apneic episodes and hypoxemia (SpO2 < 90%). Mann–Whitney test for continuous variables and Fisher’s exact test for discrete variables were used and mixed effects modeling to take into account repeated measurements on the same subject and comparing both changes within a group as a function of time and between the groups. Results There were no statistically significant differences in apneic episodes (p = 0.18) or hypoxemia (p = 0.53) between the groups. There was a statistically significant rise in etCO2 levels in both groups, but the rise was smaller in group P. There was a statistically significant rise in Bispectral Index (p = 0.002) but not modified Observer’s Assessment of Agitation/Sedation (p = 0.21) in group P. There were no statistically significant differences in any other measured parameters. Conclusions Doxapram was not effective in reducing respiratory depression caused by deep propofol sedation during ERCP. Further studies are warranted using different sedation protocols and dosing regimens. Clinical trial registration ClinicalTrials.gov ID NCT02171910.

Sa2067 Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients: A 7-Year Experience

2016 ◽  
Vol 83 (5) ◽  
pp. AB304-AB305 ◽  
Author(s):  
Parit Mekaroonkamol ◽  
Jose Nieto ◽  
Saurabh Chawla ◽  
Alvin J. Freeman ◽  
Zaid Alnoah ◽  
...  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Pediatric Patients ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy

Tu1057 SAFETY AND EFFICACY OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN NONAGENARIAN PATIENTS

2019 ◽  
Vol 89 (6) ◽  
pp. AB535
Author(s):  
Carlos Micames ◽  
Ana E. Colmenero ◽  
Fernando E. Melgar ◽  
Jorge Vera
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy
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