Incidence and molecular characterization of Glucose-6-Phosphate Dehydrogenase deficiency among neonates for newborn screening in Chaozhou, China

2014 ◽  
Vol 37 (3) ◽  
pp. 410-419 ◽  
Author(s):  
H. Yang ◽  
Q. Wang ◽  
L. Zheng ◽  
X.-F. Zhan ◽  
M. Lin ◽  
...  
Keyword(s):  
Newborn Screening ◽  
Molecular Characterization ◽  
Dehydrogenase Deficiency ◽  
Glucose 6 Phosphate Dehydrogenase

Molecular Characterization of Erythrocyte Glucose-6-Phosphate Dehydrogenase Deficiency in Al-Ain District, United Arab Emirates

1996 ◽  
Vol 46 (3) ◽  
pp. 136-141 ◽  
Author(s):  
R.A. Bayoumi ◽  
M.S.A. Nur-E-Kamal ◽  
M. Tadayyon ◽  
K.K.A. Mohamed ◽  
B.H. Mahboob ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
United Arab Emirates ◽  
Dehydrogenase Deficiency ◽  
Al Ain ◽  
Glucose 6 Phosphate Dehydrogenase

Molecular Characterization of Glucose-6-Phosphate Dehydrogenase Deficiency in Brazil

1997 ◽  
Vol 47 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Sara T.O. Saad ◽  
Tereza S.I. Salles ◽  
Helena M. Carvalho ◽  
Fernando F. Costa
Keyword(s):  
Molecular Characterization ◽  
Dehydrogenase Deficiency ◽  
Glucose 6 Phosphate Dehydrogenase

Molecular characterization of erythrocyte glucose-6-phosphate dehydrogenase deficiency in Tunisia

2008 ◽  
Vol 56 (5) ◽  
pp. 260-267 ◽  
Author(s):  
B. Ben Daoud ◽  
I. Mosbehi ◽  
C. Préhu ◽  
D. Chaouachi ◽  
R. Hafsia ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Dehydrogenase Deficiency ◽  
Glucose 6 Phosphate Dehydrogenase

scholarly journals Prevalence and molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Lue ethnic group of northern Thailand

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Suwapat Sathupak ◽  
Kamonlak Leecharoenkiat ◽  
Jatupol Kampuansai
Keyword(s):  
Ethnic Group ◽  
Ethnic Groups ◽  
Molecular Characterization ◽  
G6pd Deficiency ◽  
Dehydrogenase Deficiency ◽  
Southern China ◽  
Northern Thailand ◽  
Blood Samples ◽  
Glucose 6 Phosphate Dehydrogenase

AbstractGlucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common enzyme disorders. Prevalence and variant distribution of G6PD deficiency can vary in different regions and among differing ethnic groups. To reveal the G6PD frequency and molecular characterization among the Lue ethnic group of northern Thailand, blood samples of 296 unrelated individuals collecting from 6 Lue villages were analyzed. The observed G6PD enzyme activity ranged from 0.11 to 20.60 U/g Hb. Overall, 13.51% (40/296) of the individuals were identified as having G6PD deficiency status. The prevalence in males was 14.28% (20/140), while that of females was 12.82% (20/156). The most common G6PD variants in the Lue were the Kaiping 1388G > A (5.40%) and Canton 1376G > T (6.42%) types. Observed prevalence and variant types of the G6PD gene in the Lue population are similar to that of the Tai-Kadai speaking ethnic groups in southern China, which is consistent with their historically close line of ancestry. However, the founder effect that occurred during the Lue’s transboundary migration from China to Thailand showed its impact upon different patterns of G6PD distribution among each Lue village.

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