CHAPTER II: BIOCHEMICAL ABNORMALITIES RELATED TO CALCIUM AND PHOSPHATE METABOLISM IN CHRONIC RENAL FAILURE, WITH PARTICULAR REFERENCE TO THE EFFECT OF lα-HYDROXYVITAMIN D3

2009 ◽  
Vol 207 (S638) ◽  
pp. 18-29
1986 ◽  
Vol 32 (7) ◽  
pp. 1255-1263 ◽  
Author(s):  
J T Hindmarsh

Abstract Recent research has elucidated several of the hitherto poorly understood steps in heme synthesis. This review describes this metabolic pathway and pinpoints the enzymatic blockages in the various porphyrias. Recent advances in the understanding of the etiology of porphyria cutanea tarda are discussed, as are the abnormalities of porphyrin metabolism seen in chronic renal failure and in lead poisoning. An outline is given of the clinical and biochemical abnormalities seen in the porphyrias. Included is an algorithm to aid in the differential diagnosis of these diseases, and a brief review of the new analytical techniques available for the identification and quantification of porphyrins and their precursors in body fluids.


2019 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Beata Jarczewska-Głośnicka ◽  
Anna Kliś ◽  
Iza Maciejewska-Paszek ◽  
Patrycja Paszek ◽  
Tomasz Irzyniec

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