High fractional concentration of nitric oxide in exhaled air despite steroid treatment in asthmatic children

2005 ◽  
Vol 35 (7) ◽  
pp. 920-925 ◽  
Author(s):  
M. W. H. Pijnenburg ◽  
E. M. Bakker ◽  
S. Lever ◽  
W. C. Hop ◽  
J. C. De Jongste
Keyword(s):  
Nitric Oxide ◽  
Steroid Treatment ◽  
Asthmatic Children ◽  
Fractional Concentration ◽  
Exhaled Air

Inhibition of nitric oxide synthesis attenuates thermally induced asthma

2001 ◽  
Vol 91 (2) ◽  
pp. 703-708 ◽  
Author(s):  
C. Kotaru ◽  
M. Skowronski ◽  
A. Coreno ◽  
E. R. McFadden
Keyword(s):  
Nitric Oxide ◽  
Minute Ventilation ◽  
Isotonic Saline ◽  
Forced Expiratory Volume ◽  
Response Curves ◽  
Thermally Induced ◽  
Stimulus Response ◽  
Fractional Concentration ◽  
Exhaled Air ◽  
The Right

To determine whether the inhibition of nitric oxide (NO) synthesis attenuates thermally induced obstruction, we had 10 asthmatic volunteers perform isocapnic hyperventilation with frigid air after inhaling 1 mg of N G-monomethyl-l-arginine (l-NMMA) or isotonic saline in a blinded fashion. The challenges were identical in all respects, and there were no differences in baseline lung function [1-s forced expiratory volume (FEV1); saline 2.8 ± 0.3 liters, l-NMMA 2.9 ± 0.3 liters; P = 0.41] or prechallenge fractional concentration of nitric oxide in the exhaled air (FeNO) [saline 23 ± 6 parts/billion (ppb),l-NMMA 18 ± 4 ppb; P = 0.51]. Neither treatment had any impact on the FEV1, pulse, or blood pressure. After l-NMMA, FeNO fell significantly ( P < 0.0001), the stimulus-response curves shifted to the right, and the minute ventilation required to reduce the FEV1 20% rose 53.5% over control ( P = 0.02). The results of this study demonstrate that NO generated from the airways of asthmatic individuals may play an important role in the pathogenesis of thermally induced asthma.

Indoor Air Quality and The Fractional Concentration of Exhaled Nitric Oxide in Asthmatic Children

2013 ◽  
Vol 2013 (1) ◽  
pp. 4221
Author(s):  
Meryl Colton ◽  
Kanistha Chatterjee ◽  
Patrick Ryan ◽  
Yang Qiu ◽  
Tiina Reponen ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Air Quality ◽  
Indoor Air Quality ◽  
Indoor Air ◽  
Exhaled Nitric Oxide ◽  
Asthmatic Children ◽  
Fractional Concentration

Exhaled air temperature in asthmatic children: a mathematical evaluation

2009 ◽  
Vol 20 (2) ◽  
pp. 164-171 ◽  
Author(s):  
Massimo Pifferi ◽  
Vincenzo Ragazzo ◽  
Antonino Previti ◽  
Giovanni Pioggia ◽  
Marcello Ferro ◽  
...  
Keyword(s):  
Air Temperature ◽  
Asthmatic Children ◽  
Exhaled Air ◽  
Mathematical Evaluation

Exhaled nitric oxide measurements in normal and asthmatic children

1997 ◽  
Vol 24 (5) ◽  
pp. 312-318 ◽  
Author(s):  
C. A. Byrnes ◽  
S. Dinarevic ◽  
E. A. Shinebourne ◽  
P. J. Barnes ◽  
A. Bush
Keyword(s):  
Nitric Oxide ◽  
Exhaled Nitric Oxide ◽  
Asthmatic Children

Exaled nitric oxide and air trapping correlation in asthmatic children

Allergy ◽  
2005 ◽  
Vol 60 (11) ◽  
pp. 1436-1439 ◽  
Author(s):  
L. Mappa ◽  
F. Cardinale ◽  
R. Camodeca ◽  
M. L. Tortorella ◽  
A. Pietrobelli ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Air Trapping ◽  
Asthmatic Children

STEROID TREATMENT OF ASTHMATIC CHILDREN

The Lancet ◽  
1966 ◽  
Vol 288 (7477) ◽  
pp. 1354-1356 ◽  
Author(s):  
N.M. Jacoby
Keyword(s):  
Steroid Treatment ◽  
Asthmatic Children

Association of Indoor Air Pollution with Rhinitis Symptoms, Atopy and Nitric Oxide Levels in Exhaled Air

2010 ◽  
Vol 153 (4) ◽  
pp. 403-412 ◽  
Author(s):  
Lars-Georg Hersoug ◽  
Lise Lotte N. Husemoen ◽  
Simon Francis Thomsen ◽  
Torben Sigsgaard ◽  
Betina H. Thuesen ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Air Pollution ◽  
Indoor Air ◽  
Indoor Air Pollution ◽  
Exhaled Air
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