Characteristics of Cytotoxic T Lymphocytes Directed to Influenza Virus Haemagglutinin Elicited by Immunization with Muramyldipeptide-Influenza Liposome Vaccine

1995 ◽  
Vol 41 (1) ◽  
pp. 1-10 ◽  
Author(s):  
H. HNUMA ◽  
K. NEROME ◽  
Y. YOSHIOKA ◽  
K. OKINAGA
Keyword(s):  
Influenza Virus ◽  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes ◽  
Influenza Virus Haemagglutinin ◽  
Virus Haemagglutinin

scholarly journals The conformation of influenza virus haemagglutinin

FEBS Letters ◽  
1977 ◽  
Vol 80 (1) ◽  
pp. 57-60 ◽  
Author(s):  
M.T. Flanagan ◽  
J.J. Skehel
Keyword(s):  
Influenza Virus ◽  
Influenza Virus Haemagglutinin ◽  
Virus Haemagglutinin

scholarly journals HLA restriction of human cytotoxic T lymphocytes specific for influenza virus. Poor recognition of virus associated with HLA A2.

1978 ◽  
Vol 148 (6) ◽  
pp. 1458-1467 ◽  
Author(s):  
A McMichael
Keyword(s):  
Influenza Virus ◽  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes ◽  
Influenza A ◽  
Human Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
The Other ◽  
Target Cells ◽  
Surface Molecules ◽  
Human Peripheral Blood Lymphocytes

Cytotoxic T lymphocytes (CTL), specific for influenza A/X31 virus, were generated from human peripheral blood lymphocytes. These CTL lysed target cells that were infected with the same virus and that shared HLA A or B locus antigens. Minimal lysis was observed when HLA-D antigens were shared. Not all HLA A and B antigens were equally effective. Efficient lysis of target cells was seen when HLA A1, A3, B7, B8, B27 and BW21 were shared with the CTL, but when HLA A2 was the only shared antigen lysis was usually minimal. This deficiency in CTL function associated with HLA A2 was not absolute. It is suggested that the function of this antigen might be influenced by other surface molecules on the cell and in particular the other HLA products.

scholarly journals Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin

Nature ◽  
1984 ◽  
Vol 311 (5987) ◽  
pp. 678-680 ◽  
Author(s):  
M. Knossow ◽  
R. S. Daniels ◽  
A. R. Douglas ◽  
J. J. Skehel ◽  
D. C. Wiley
Keyword(s):  
Influenza Virus ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Three Dimensional Structure ◽  
Influenza Virus Haemagglutinin ◽  
Virus Haemagglutinin

scholarly journals Studies on the Structure of the Influenza Virus Haemagglutinin at the pH of Membrane Fusion

1988 ◽  
Vol 69 (11) ◽  
pp. 2785-2795 ◽  
Author(s):  
R. W. H. Ruigrok ◽  
A. Aitken ◽  
L. J. Calder ◽  
S. R. Martin ◽  
J. J. Skehel ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Influenza Virus Haemagglutinin ◽  
Virus Haemagglutinin
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