Heterogeneous Binding of Sigma Radioligands in the Rat Brain and Liver: Possible Relationship to Subforms of Cytochrome P-450

1991 ◽  
Vol 68 (4) ◽  
pp. 293-301 ◽  
Author(s):  
Svante B. Ross
Keyword(s):  
Rat Brain ◽  
Rat Brain And Liver ◽  
Cytochrome P 450

scholarly journals Enzymic synthesis of ether types of choline and ethanolamine phosphoglycerides by microsomal fractions from rat brain and liver

1977 ◽  
Vol 18 (1) ◽  
pp. 53-58
Author(s):  
A Radominska-Pyrek ◽  
J Strosznajder ◽  
Z Dabrowiecki ◽  
G Goracci ◽  
T Chojnacki ◽  
...  
Keyword(s):  
Rat Brain ◽  
Enzymic Synthesis ◽  
Ethanolamine Phosphoglycerides ◽  
Rat Brain And Liver

Respiration of Rat Brain and Liver at Temperatures above 37°C

1951 ◽  
Vol 24 (2) ◽  
pp. 163-166
Author(s):  
Robert L. Jasper ◽  
James W. Archdeacon
Keyword(s):  
Rat Brain ◽  
Rat Brain And Liver

The Effect of Aluminum on Rat Brain and Liver Quinolinic Acid Concentrations

1991 ◽  
pp. 459-462
Author(s):  
J. H. Connick ◽  
G. Lombardi ◽  
F. Moroni ◽  
E. Hall ◽  
A. Taylor ◽  
...  
Keyword(s):  
Rat Brain ◽  
Quinolinic Acid ◽  
Rat Brain And Liver

Different Regiospecificity in the Hydroxylation of the Antidepressant Desmethylimipramine Between Rat Brain and Liver

1992 ◽  
Vol 71 (6) ◽  
pp. 416-419 ◽  
Author(s):  
T. Hansson ◽  
C. Bahr ◽  
M. Marklund ◽  
J.-O. Svensson ◽  
M. Ingelman-Sundberg ◽  
...  
Keyword(s):  
Rat Brain ◽  
Rat Brain And Liver

The metabolism of a tryptophan load in rat brain and liver. The influence of hydrocortisone and allopurinol

1976 ◽  
Vol 25 (23) ◽  
pp. 2599-2612 ◽  
Author(s):  
Michael H. Joseph ◽  
Simon N. Young ◽  
Gerald Curzon
Keyword(s):  
Rat Brain ◽  
Rat Brain And Liver

DNA Polymerases of Newborn Rat Brain and Liver

1971 ◽  
Vol 49 (8) ◽  
pp. 978-986 ◽  
Author(s):  
A. D. Bharucha ◽  
M. R. V. Murthy
Keyword(s):  
Rat Brain ◽  
Specific Activity ◽  
Hydrolytic Enzymes ◽  
Polymerase Activity ◽  
Newborn Rat ◽  
Newborn Brain ◽  
Rat Brain And Liver ◽  
Mammalian Tissues ◽  
Optimum Ph ◽  
Sulfhydryl Compounds

DNA polymerase activity was found to be present in appreciable quantities in the extracts of whole tissue (TS) as well as of nuclei (NS) isolated from newborn rat brain and liver. The NS fractions of either of the two tissues exhibited a higher specific activity per unit protein than the corresponding TS fractions. The optimum pH requirements as well as the ability to support DNA synthesis over a long period indicate that the NS fractions were also comparatively less contaminated by interfering substances than the TS fractions.The reaction requirements for the incorporation of TMP residues into DNA by the NS fractions of newborn rat brain and liver and the effect of various inhibitors and hydrolytic enzymes on this reaction were also investigated. These extracts resembled preparations from other mammalian tissues in that they exhibited absolute requirements for the primer DNA, the four complimentary deoxynucleoside triphosphates, and Mg2+ ions. When three of the four deoxynucleoside triphosphates were omitted and only TTP-2-14C was added to the reaction mixture, a limited incorporation of TMP-2-14C into DNA occurred. Other investigations such as the effect of actinomycin and of sulfhydryl compounds revealed that a large part of incorporation by the TS and NS fractions of newborn brain and liver was due to the replicative DNA nucleotidyltransferase enzyme.

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