Furosemide and Ethacrynic Acid: Risk Factors for the Occurrence of Serum Electrolyte Abnormalities and Metabolic Alkalosis in Newborns and Infants

1989 ◽  
Vol 78 (1) ◽  
pp. 133-135 ◽  
Author(s):  
N. Laudignon ◽  
A. Ciampi ◽  
L. Coupal ◽  
S. Chemtob ◽  
J. V. Aranda
Keyword(s):  
Risk Factors ◽  
Metabolic Alkalosis ◽  
Ethacrynic Acid ◽  
Serum Electrolyte ◽  
Electrolyte Abnormalities

Electrolyte and other physiological abnormalities in patients with bulimia

1983 ◽  
Vol 13 (2) ◽  
pp. 273-278 ◽  
Author(s):  
James E. Mitchell ◽  
Richard L. Pyle ◽  
Elke D. Eckert ◽  
Dorothy Hatsukami ◽  
Richard Lentz
Keyword(s):  
Eating Disorder ◽  
Metabolic Alkalosis ◽  
Serum Amylase ◽  
Elevated Serum ◽  
Screening Tests ◽  
Amylase Level ◽  
Serum Electrolyte ◽  
Serum Amylase Level ◽  
Physiological Abnormalities ◽  
Electrolyte Abnormalities

SYNOPSISThe frequencies of various forms of eating-related behaviour (such as vomiting and laxative abuse) are reported for a series of non-anorectic bulimia patients seen for evaluation in an eating disorders clinic. The results of serum electrolyte, glucose and other screening tests in these patients are presented. Electrolyte abnormalities were found in 82 of the 168 patients (48·8%) who were diagnosed as having either bulimia or atypical eating disorder. The most common abnormality was metabolic alkalosis (27·4%); hypochloremia (23·8%) and hypokalemia (13·7%) were also commonly seen. No significant blood sugar abnormalities were encountered. An elevated serum amylase level was found to be associated with frequent binge-eating and vomiting behaviour. The pathophysiology of electrolyte abnormalities in this patient group is briefly reviewed.

scholarly journals Anesthetic Management of a Patient with Sustained Severe Metabolic Alkalosis and Electrolyte Abnormalities Caused by Ingestion of Baking Soda

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Jose Soliz ◽  
Jeffrey Lim ◽  
Gang Zheng
Keyword(s):  
Head And Neck Cancer ◽  
Alternative Medicine ◽  
Head And Neck ◽  
Neck Cancer ◽  
Metabolic Alkalosis ◽  
Anesthetic Management ◽  
Herbal Remedies ◽  
Anesthetic Care ◽  
Electrolyte Abnormalities

The use of alternative medicine is prevalent worldwide. However, its effect on intraoperative anesthetic care is underreported. We report the anesthetic management of a patient who underwent an extensive head and neck cancer surgery and presented with a severe intraoperative metabolic alkalosis from the long term ingestion of baking soda and other herbal remedies.

Influence of acute and chronic respiratory alkalosis on preexisting chronic metabolic alkalosis

1990 ◽  
Vol 258 (3) ◽  
pp. F479-F485
Author(s):  
N. E. Madias ◽  
J. J. Cohen ◽  
H. J. Adrogue
Keyword(s):  
Metabolic Alkalosis ◽  
Ethacrynic Acid ◽  
Chronic Phase ◽  
Repeated Administration ◽  
Respiratory Alkalosis ◽  
Carbon Dioxide Tension ◽  
Restricted Diet ◽  
Bicarbonate Concentration ◽  
Normal Humans ◽  
Renal Responses

The severity of the alkalemia produced by a reduction in arterial carbon dioxide tension (PaCO2) in normal humans and animals is ameliorated by buffer and renal responses that diminish the levels of plasma bicarbonate concentration ([HCO3-]p). These adjustments have even greater potential importance in preventing extreme degrees of alkalemia when hypocapnia occurs in the presence of an initially elevated [HCO3-]p (mixed respiratory and metabolic alkalosis). The aim of the present study was to characterize the acute (approximately 3 h) and chronic (5 days) acid-base effects of respiratory alkalosis when superimposed on chronic metabolic alkalosis. Ten dogs were made alkalotic by the repeated administration of ethacrynic acid and the provision of a chloride-restricted diet. Hypocapnia (delta PaCO2 = 10 mmHg) was then superimposed by exposing the animals to 11% O2 in an environmental chamber. A large fall in [HCO3-]p occurred in the acute hypocapnic phase that was further augmented in the chronic phase; the corresponding delta [HCO3-]p/delta PaCO2 slopes were 0.43 and 0.71 meq.l-1.mmHg-1, respectively, values substantially larger than those previously reported for hypocapnia in normals as well as in animals with preexisting HCl acidosis. Hyperlactatemia was responsible, on average, for 43% of the decrement in [HCO3-]p during acute hypocapnia but for only 20% of the delta [HCO3-]p during the chronic phase of the study. The striking decrement in [HCO3-]p observed in response to the chronic reduction in PaCO2 was sufficient not only to prevent the development of extreme alkalemia but also to offset entirely the effect of hypocapnia on plasma [H+].

101: QTc Prolongation and Serum Electrolyte Abnormalities In Emergency Department Patients

2010 ◽  
Vol 56 (3) ◽  
pp. S34
Author(s):  
S.L. House ◽  
I. Vitkovitsky ◽  
A. Kim ◽  
M. Treaster ◽  
J. Burkett ◽  
...  
Keyword(s):  
Emergency Department ◽  
Qtc Prolongation ◽  
Serum Electrolyte ◽  
Emergency Department Patients ◽  
Electrolyte Abnormalities

scholarly journals Hypercalcemia and Milk Alkali Syndrome: A Case Report

2020 ◽  
Vol 3 (12) ◽  
pp. 380-382
Author(s):  
Kriti Seth ◽  
Nalini Kharbanda
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Renal Insufficiency ◽  
Metabolic Alkalosis ◽  
Elderly Subjects ◽  
Calcium Supplements

A triad of metabolic alkalosis, hypercalcemia and renal insufficiency constitutes the milk alkali syndrome. Elderly subjects, especially those on drugs that GFR are more prone to acquire this syndrome. Those who take calcium supplements have high chances of developing milk alkali syndrome and this stands amongst the top five causes of hypercalcemia. Herein we present a case of hypercalcemia who was taking only small amount of calcium supplements but had a few concomitant risk factors.

Pre- and Postoperative Fluid Management in Infancy

1989 ◽  
Vol 11 (5) ◽  
pp. 153-158
Author(s):  
Russell W. Chesney ◽  
Israel Zelikovic
Keyword(s):  
Metabolic Acidosis ◽  
Parenteral Nutrition ◽  
Maintenance Therapy ◽  
Metabolic Alkalosis ◽  
Fluid Management ◽  
Fluid Replacement ◽  
Emergency Procedure ◽  
Volume Depletion ◽  
Fluid And Electrolyte Management ◽  
Electrolyte Abnormalities

The fluid and electrolyte management of the infant either before or following surgery is not difficult if the several principles are carefully followed: (1) Fluid requirements include maintenance therapy, correction of ongoing losses, and replacement of deficit losses. (2) Calculation for fluid requirements in the postoperative period will include maintenance therapy, correction of ongoing losses, and provision of fluid lost by internal shifts. (3) Maintenance needs for fluid in infants equals 100 to 120 mL/kg per 24 hours, and Na+ at 3 mEq/kg per 24 hours and K+ at 2 to 3 mEq/kg per 24 hours are needed. (4) Infants with pyloric stenosis should be anticipated to have hypokalemic, hypochloremic metabolic alkalosis, and dehydration. These electrolyte abnormalities should be corrected before surgery is performed. A pyloromyotomy is not an emergency procedure. (5) Ileostomy losses can equal 90 mEq/L of Na+ and up to 110 mEq/L of HCO3. Thus, adequate fluid replacement results in volume depletion and metabolic acidosis. (6) Children whose nutritional status is marginal and whose bowels cannot be used for nutrient absorption should receive their fluid and electrolyte needs as part of a total parenteral nutrition program.

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