First‐in‐man Valve‐in‐Valve with the new balloon‐expandable Myval transcatheter heart valve in a failed sutureless Perceval bioprosthesis

Author(s):  
Igor Belluschi ◽  
Nicola Buzzatti ◽  
Paolo Denti ◽  
Vittorio Romano ◽  
Antonio Miceli ◽  
...  
2020 ◽  
Vol 5 (11) ◽  
pp. 1245 ◽  
Author(s):  
Brian Whisenant ◽  
Samir R. Kapadia ◽  
Mackram F. Eleid ◽  
Susheel K. Kodali ◽  
James M. McCabe ◽  
...  

Reports ◽  
2020 ◽  
Vol 3 (2) ◽  
pp. 7
Author(s):  
Muhammad Ajmal ◽  
Sridhar Reddy ◽  
Ranjith Shetty ◽  
Toshinobu Kazui ◽  
Kapildeo Lotun

Currently, transcatheter aortic valve replacements within degenerated surgical bioprosthetic aortic valves (valve in valve) are increasing in frequency with studies supporting their safety and efficacy. We present the rare case of a patient requiring a second transcatheter bioprosthetic aortic valve placed within a previously placed degenerated transcatheter aortic valve, which was implanted in a degenerated surgical bioprosthetic aortic valve. The procedure was performed using a percutaneous cardiopulmonary bypass with TandemLife for hemodynamic support.


2016 ◽  
Vol 18 (5) ◽  
pp. 89-92 ◽  
Author(s):  
T.E. Imaev ◽  
◽  
A.E. Komlev ◽  
A.S. Kolegaev ◽  
P.M. Lepilin ◽  
...  

2016 ◽  
Vol 68 (18) ◽  
pp. B271 ◽  
Author(s):  
Sami Alnasser ◽  
Asim Cheema ◽  
Eric Horlick ◽  
Nicolas Van Mieghem ◽  
Gudrun Feuchtner ◽  
...  

2017 ◽  
Vol 12 (01) ◽  
pp. 40 ◽  
Author(s):  
Ren Jie Yao ◽  
Matheus Simonato ◽  
Danny Dvir ◽  
◽  
◽  
...  

Bioprosthetic surgical valves are increasingly implanted during cardiac surgery, instead of mechanical valves. These tissue valves are associated with limited durability and as a result transcatheter valve-in-valve procedures are performed to treat failed bioprostheses. A relatively common adverse event of aortic valve-in-valve procedures is residual stenosis. Larger surgical valve size, supra-annular transcatheter heart valve type, as well as higher transcatheter heart valve implantation depth, have all been shown to reduce the incidence of elevated post-procedural gradients. With greater understanding of technical considerations and surgical planning, valve-invalve procedures could be more effective and eventually may become the standard of care for our increasingly ageing and comorbid population with failed surgical bioprostheses.


2021 ◽  
Vol 16 (Supplement 1) ◽  
pp. 1-4
Author(s):  
Dariusz Jagielak ◽  
Radoslaw Targonski ◽  
Dariusz Ciecwierz

Cerebral embolic protection (CEP) devices aim to reduce the risk of periprocedural cerebrovascular events during transcatheter aortic valve implantation (TAVI). Here, the authors describe the first-in-human experience with the ProtEmbo Cerebral Protection System (Protembis), a next-generation CEP device, during TAVI. This case is part of a larger European trial evaluating the safety and performance of this device. After deployment of the ProtEmbo in the aortic arch, a first transcatheter heart valve was implanted. Despite postdilatation, moderate to severe aortic regurgitation persisted. The operating team decided to perform a valve-in-valve procedure using a second transcatheter heart valve. The ProtEmbo demonstrated good coverage of all three head vessels and no interaction with TAVI catheters in the aortic arch throughout the entire procedure. No adverse events were observed during hospitalisation or follow-up, and there was a significant reduction in aortic regurgitation at follow-up echocardiography. Despite a challenging overall procedure with presumably high embolic burden, diffusion-weighted MRI at follow-up showed a low number (n=3) and volume (156 mm3) of new hyperintense lesions. The first-in-human use of the ProtEmbo was safe and feasible, despite a challenging TAVI valve-in-valve procedure.


2019 ◽  
Vol 14 (3) ◽  
pp. 147-151 ◽  
Author(s):  
John Phineas O’Donnell ◽  
Cróchán J O’Sullivan

The limited durability of surgical bioprostheses, combined with an ageing population, has led to an increasing demand for replacing degenerated bioprosthetic surgical heart valves, which is projected to increase. Valve-in-valve transcatheter aortic valve implantation involves implanting a transcatheter heart valve within a degenerated bioprosthetic surgical heart valve. A significant minority of patients, however, are left with a suboptimal haemodynamic result with high residual gradients. This is more common with smaller surgical bioprostheses, and may be associated with a worse prognosis. The novel concept of fracturing the previously implanted bioprosthetic surgical heart valve during valve- in-valve transcatheter aortic valve implantation to create a more favourable haemodynamic profile has shown great promise, particularly in smaller valves. Herein, we describe the benefits, limitations and potential complications of this novel approach.


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