scholarly journals Reduced iron export associated with hepcidin resistance can explain the iron overload spectrum in ferroportin disease

2020 ◽  
Vol 40 (8) ◽  
pp. 1941-1951 ◽  
Author(s):  
André Viveiros ◽  
Marlene Panzer ◽  
Nadja Baumgartner ◽  
Benedikt Schaefer ◽  
Armin Finkenstedt ◽  
...  
Keyword(s):  
Iron Overload ◽  
Iron Export

scholarly journals Iron Imports. III. Transfer of iron from the mucosa into circulation

2006 ◽  
Vol 290 (1) ◽  
pp. G1-G6 ◽  
Author(s):  
Marianne Wessling-Resnick
Keyword(s):  
Iron Overload ◽  
Dietary Iron ◽  
Critical Step ◽  
Iron Assimilation ◽  
Iron Export

Transfer of iron from the mucosa is a critical step in dietary iron assimilation that is tightly regulated to ensure the appropriate amount of iron is absorbed to meet the body's demands. Too much iron is highly toxic, and failure to properly control intestinal iron export causes iron overload associated with hereditary forms of hemochromatosis. One form of genetic iron overload, ferroportin disease, originates due to defects in ferroportin, the membrane iron exporter. Ferroportin acts in conjunction with the intestinal ferroxidase hephaestin to mediate release of iron from the enterocyte. How iron is then acquired by transferrin and released into circulation remains an unknown step in this process.

HFE genotype and the insulin resistance syndrome among subjects with iron overload

2001 ◽  
Vol 120 (5) ◽  
pp. A565-A565
Author(s):  
J TALWALKAR ◽  
H TORGERSON ◽  
D BRANDHAGEN
Keyword(s):  
Insulin Resistance ◽  
Iron Overload ◽  
Insulin Resistance Syndrome

Abstract #914: Polyglandular Autoimmune Syndrome in a Patient with Sickle Cell Anemia and Iron Overload

2005 ◽  
Vol 11 ◽  
pp. 85
Author(s):  
Allison Elise Kerr ◽  
Wolali Odonkor ◽  
Gail Nunlee-Bland ◽  
Juanita Archer ◽  
Anitha Kolukula ◽  
...  
Keyword(s):  
Iron Overload ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Polyglandular Autoimmune Syndrome ◽  
Autoimmune Syndrome

Iron overload in cutaneous porphyria

1969 ◽  
Vol 124 (2) ◽  
pp. 190-196 ◽  
Author(s):  
G. F. Sauer
Keyword(s):  
Iron Overload

Transferrin Saturation Defines Distinct Subtypes of Dysmetabolic Iron Overload Syndrome

2016 ◽  
Vol 54 (05) ◽  
Author(s):  
A Viveiros ◽  
A Finkenstedt ◽  
B Schäfer ◽  
B Henninger ◽  
W Vogel ◽  
...  
Keyword(s):  
Iron Overload ◽  
Transferrin Saturation
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