scholarly journals Prucalopride induces high‐amplitude propagating contractions in the colon of patients with chronic constipation: a randomized study

2016 ◽  
Vol 28 (9) ◽  
pp. 1341-1348 ◽  
Author(s):  
P. B. Miner ◽  
M. Camilleri ◽  
D. Burton ◽  
H. Achenbach ◽  
H. Wan ◽  
...  
Keyword(s):  
Chronic Constipation ◽  
Randomized Study ◽  
High Amplitude ◽  
Propagating Contractions

Segmental colonic dilation is associated with premature termination of high-amplitude propagating contractions in children with intractable functional constipation

2017 ◽  
Vol 29 (10) ◽  
pp. e13110 ◽  
Author(s):  
I. J. N. Koppen ◽  
B. P. Thompson ◽  
E. J. Ambeba ◽  
V. A. Lane ◽  
D. G. Bates ◽  
...  
Keyword(s):  
Premature Termination ◽  
Functional Constipation ◽  
High Amplitude ◽  
Propagating Contractions

Solid-state vs water-perfused catheters to measure colonic high-amplitude propagating contractions

2012 ◽  
Vol 24 (4) ◽  
pp. 345-e167 ◽  
Author(s):  
O. Liem ◽  
R. E. Burgers ◽  
F. L. Connor ◽  
M. A. Benninga ◽  
S. N. Reddy ◽  
...  
Keyword(s):  
Solid State ◽  
High Amplitude ◽  
Propagating Contractions ◽  
Perfused Catheters

scholarly journals Effect of Colon Transection on Spontaneous and Meal-Induced High-Amplitude–Propagating Contractions in Children

2015 ◽  
Vol 60 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Courtney Jacobs ◽  
Sharon Wolfson ◽  
Carlo Di Lorenzo ◽  
Jose Cocjin ◽  
Javier Monagas ◽  
...  
Keyword(s):  
High Amplitude ◽  
Propagating Contractions

819 Effect of Colon Transection on Spontaneous High-Amplitude-Propagating Contractions in Children

2014 ◽  
Vol 146 (5) ◽  
pp. S-143
Author(s):  
Sharon Wolfson ◽  
Courtney Jacobs ◽  
Javier J. Monagas ◽  
Carlo Di Lorenzo ◽  
Jose Cocjin ◽  
...  
Keyword(s):  
High Amplitude ◽  
Propagating Contractions

Duodenal and proximal jejunal motility inhibition associated with bisacodyl induced colonic high amplitude propagating contractions

2021 ◽  
Author(s):  
Phil G Dinning ◽  
Lukasz Wiklendt ◽  
Marcello C. Costa ◽  
Simon J. H. Brookes ◽  
Maureen Amicangelo ◽  
...  
Keyword(s):  
Small Bowel ◽  
Contractile Activity ◽  
Colonic Motility ◽  
Mean Amplitude ◽  
High Amplitude ◽  
Motor Patterns ◽  
Bowel Motility ◽  
Small Bowel Motility ◽  
Colonic Manometry ◽  
Propagating Contractions

Bisacodyl is a stimulant laxative often used in manometric studies of pediatric constipation to determine if it can initiate propulsive high amplitude propagating contractions. While the effects of bisacodyl infusion on colonic motility are well described, the effects of the drug on other regions of the gut after colonic infusion are not known. The aim of the present study was to characterize the effects of bisacodyl on both colonic and small bowel motility. Methods. Twenty seven children (9.3 + 1.2 years) undergoing simultaneous high resolution antroduodenal and colonic manometry were included. Small bowel and colonic motor patterns were assessed prior to and after colonic infusion of bisacodyl. Patients were divided into 2 groups; responders and non-responders based on the presence of high amplitude propagating contractions (HAPC) after bisacodyl infusion. Results. Nineteen patients were responders. 188 post-bisacodyl HAPCs were identified with a mean count of 10.4 ± 5.5 (range, 3 -22), at a frequency of 0.6 ± 0.2/min and mean amplitude of 119.8 ± 23.6 mmHg.No motor patterns were induced in the small bowel. However, in the 19 responders the onset of HAPCs was associated with a significant decrease in small bowel contractile activity. In the non-responders there was no detectable change in small bowel motility after bisacodyl infusion. Conclusion. Bisacodyl induced HAPCs are associated with a significant reduction in small bowel motility probably mediated by extrinsic sympathetic reflex pathways. This inhibition is potentially related to rectal distension, caused by the HAPC anal propulsion of colonic content.

scholarly journals Efficacy and tolerability of peg-only laxative on faecal impaction and chronic constipation in children. A controlled double blind randomized study vs a standard peg-electrolyte laxative

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Francesco Savino ◽  
Serena Viola ◽  
Maiullari Erasmo ◽  
Giovanni Di Nardo ◽  
Salvatore Oliva ◽  
...  
Keyword(s):  
Chronic Constipation ◽  
Randomized Study ◽  
Double Blind ◽  
Faecal Impaction

scholarly journals Colonic Migrating Motor Complexes, High Amplitude Propagating Contractions, Neural Reflexes and the Importance of Neuronal and Mucosal Serotonin

2014 ◽  
Vol 20 (4) ◽  
pp. 423-446 ◽  
Author(s):  
Terence K Smith ◽  
Kyu Joo Park ◽  
Grant W Hennig
Keyword(s):  
High Amplitude ◽  
Propagating Contractions
Sign in / Sign up

Export Citation Format

Share Document