Oral mucous membrane pemphigoid and pemphigus vulgaris-a retrospective two-center cohort study

Oral Diseases ◽  
2017 ◽  
Vol 23 (4) ◽  
pp. 498-504 ◽  
Author(s):  
AS Sultan ◽  
A Villa ◽  
AP Saavedra ◽  
NS Treister ◽  
S-B Woo

Author(s):  
Narjes Akbari ◽  
Ghazaleh Mozafari ◽  
Hamid Abbaszadeh

Mucous membrane pemphigoid (MMP) is a rare inflammatory, autoimmune, and subepithelial vesiculobullous disease in which tissue-bound autoantibodies are produced against one or more components of the basement membrane. Oral lesions of the pemphigoid begin in the form of vesicles or bullae that often involve throughout the mouth but may be confined to specific areas, especially the gingiva, in a pattern known as desquamative gingivitis. The positive Nikolsky's sign is characteristic of pemphigus vulgaris, in which a blister can appear on the normal-appearing skin if exerting lateral pressure, and is very rare in the mucosa and other vesiculobullous diseases. Here we report a case of mucous membrane pemphigoid that developed as desquamated gingivitis in a 46-year-old woman with positive Nikolsky's sign in the gingival mucosa. In the histopathologic view, a subepithelial cleft was observed. The results of direct and indirect immunofluorescence tests and related therapeutic interventions are also presented. Positive Nikolsky's sign can be observed in the mucosa as well as in the mucous membrane pemphigoid in addition to pemphigus vulgaris, and vesiculobullous lesions should be diagnosed based on the sum of clinical, histopathological, and immunofluorescence findings.



2003 ◽  
Vol 139 (8) ◽  
Author(s):  
Virginia C. Hall ◽  
Thomas J. Liesegang ◽  
David A. Kostick ◽  
Donald P. Lookingbill


2006 ◽  
Vol 86 (4) ◽  
pp. 351-354 ◽  
Author(s):  
SV Lourenço ◽  
P Boggio ◽  
LE Martins ◽  
CG Santi ◽  
V Aoki ◽  
...  


1996 ◽  
Vol 12 (2) ◽  
pp. 191
Author(s):  
Yuji Shirakata ◽  
Masayuki Amagai ◽  
Yasushi Hanakawa ◽  
Takeji Nishikawa ◽  
Koji Hashimoto


Proceedings ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 2
Author(s):  
Paola Carcieri

Desquamative gingivitis (DG) isn’t a specific disorder; it simply represents the gingival manifestation associated with some heterogeneous mucocutaneous disorders, such as oral lichen planus (OLP), mucous membrane pemphigoid (MMP), pemphigus vulgaris (PV), plasma cell gingivitis (PCG) and few others. [...]



2019 ◽  
Vol 182 (3) ◽  
pp. 747-753 ◽  
Author(s):  
B. Carey ◽  
S. Joshi ◽  
A. Abdelghani ◽  
J. Mee ◽  
M. Andiappan ◽  
...  


Author(s):  
RAQUEL D´AQUINO GARCIA CAMINHA ◽  
NATALIA GARCIA SANTAELLA ◽  
BRENA RODRIGUES MANZANO ◽  
EDUARDO STEDILE FIAMONCINI ◽  
DAYANNE SIMõES FERREIRA SANTOS ◽  
...  


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