Periodontal status and clinical outcomes in kidney transplant recipients: A systematic review

Oral Diseases ◽  
2019 ◽  
Vol 26 (1) ◽  
pp. 22-34 ◽  
Author(s):  
Danila L. Nunes‐dos‐Santos ◽  
Samira V. Gomes ◽  
Vandilson P. Rodrigues ◽  
Antonio L. A. Pereira
2022 ◽  
Vol 48 (1) ◽  
pp. 17-29
Author(s):  
Made Dyah Vismita Indramila Duarsa ◽  
◽  
Yenny Kandarini ◽  
Niwanda Yogiswara ◽  
Yudhistira Pradnyan Kloping ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Saeid Eslami ◽  
Farnaz Khoshrounejad ◽  
Reza Golmakani ◽  
Zhila Taherzadeh ◽  
Fariba Tohidinezhad ◽  
...  

Abstract Background Kidney transplant outcomes are broadly associated with transplant recipients’ capacity in following a complex and continuous self-management regimen. Health information technology has the potential to empower patients. This systematic review aimed to determine the impacts of IT-based interventions for self-management in kidney transplant recipients. Methods A comprehensive investigation was performed in MEDLINE (via PubMed) and EMBASE (via Scopus) in April 2019. Eligible studies were the randomized controlled trials which aimed to design an automated IT-based intervention. All English papers including adult kidney transplant recipients were included. To assess the clinical trial’s quality, Cochrane Collaboration’s assessment tool was employed. The articles were integrated based on category of outcomes, characteristics of interventions, and their impact. The interventions were classified based on the used IT-based tools, including smart phones, coverage tools, computer systems, and a combination of several tools. The impact of interventions was defined as: (1) positive effect (i.e. statistically significant), and (2) no effect (i.e. not statistically significant). Results A total of 2392 articles were retrieved and eight publications were included for full-text analysis. Interventions include those involving the use of computerized systems (3 studies), smart phone application (3 studies), and multiple components (2 studies). The studies evaluated 30 outcomes in total, including 24 care process and 6 clinical outcomes. In 18 (80%) out of 30 outcomes, interventions had a statistically significant positive effect, 66% in process and 33% in clinical outcomes. Conclusions IT-based interventions (e.g. mobile health applications, wearable devices, and computer systems) can improve self-management in kidney transplant recipients (including clinical and care process outcomes). However, further evaluation studies are required to quantify the impact of IT-based self-management interventions on short- and long-term clinical outcomes as well as health care costs and patients' quality of life.


Author(s):  
Maria Aurora Posadas Salas ◽  
Rafael David Rodriguez-Abreu ◽  
Prince Amaechi ◽  
Vinaya Rao ◽  
Karim Soliman ◽  
...  

2019 ◽  
Vol 103 (8) ◽  
pp. 1705-1713 ◽  
Author(s):  
Tracey Ying ◽  
Germaine Wong ◽  
Wai H. Lim ◽  
Philip Clayton ◽  
John Kanellis ◽  
...  

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2893 ◽  
Author(s):  
Rossana Rosa ◽  
Jose F. Suarez ◽  
Marco A. Lorio ◽  
Michele I. Morris ◽  
Lilian M. Abbo ◽  
...  

Background: Antiretroviral therapy (ART) poses challenging drug-drug interactions with immunosuppressant agents in transplant recipients.  We aimed to determine the impact of specific antiretroviral regimens in clinical outcomes of HIV+ kidney transplant recipients. Methods: A single-center, retrospective cohort study was conducted at a large academic center. Subjects included 58 HIV- to HIV+ adult, first-time kidney transplant patients. The main intervention was ART regimen used after transplantation.  The main outcomes assessed at one- and three-years were: patient survival, death-censored graft survival, and biopsy-proven acute rejection; we also assessed serious infections within the first six months post-transplant. Results: Patient and graft survival at three years were both 90% for the entire cohort. Patients receiving protease inhibitor (PI)-containing regimens had lower patient survival at one and three years than patients receiving PI-sparing regimens: 85% vs. 100% (p=0.06) and 82% vs. 100% (p=0.03), respectively. Patients who received PI-containing regimens had twelve times higher odds of death at 3 years compared to patients who were not exposed to PIs (odds ratio, 12.05; 95% confidence interval, 1.31-1602; p=0.02).  Three-year death-censored graft survival was lower in patients receiving PI vs. patients on PI-sparing regimens (82 vs 100%, p=0.03). Patients receiving integrase strand transfer inhibitors-containing regimens had higher 3-year graft survival. There were no differences in the incidence of acute rejection by ART regimen. Individuals receiving PIs had a higher incidence of serious infections compared to those on PI-sparing regimens (39 vs. 8%, p=0.01). Conclusions: PI-containing ART regimens are associated with adverse outcomes in HIV+ kidney transplant recipients.


2016 ◽  
Vol 28 (6) ◽  
pp. 1886-1897 ◽  
Author(s):  
Seokwoo Park ◽  
Eunjeong Kang ◽  
Sehoon Park ◽  
Yong Chul Kim ◽  
Seung Seok Han ◽  
...  

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