scholarly journals Black rats ( Rattus rattus ) as potential reservoir hosts for Rift Valley fever phlebovirus: experimental infection results in viral replication and shedding without clinical manifestation

2021 ◽  
Author(s):  
Franziska Stoek ◽  
Melanie Rissmann ◽  
Reiner Ulrich ◽  
Martin Eiden ◽  
Martin H. Groschup
Keyword(s):  
Viral Replication ◽  
Clinical Manifestation ◽  
Experimental Infection ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rattus Rattus ◽  
Valley Fever ◽  
Potential Reservoir ◽  
Reservoir Hosts ◽  
Black Rats

scholarly journals Experimental Infection of Calves by Two Genetically-Distinct Strains of Rift Valley Fever Virus

Viruses ◽  
2016 ◽  
Vol 8 (5) ◽  
pp. 145 ◽  
Author(s):  
William Wilson ◽  
A. Davis ◽  
Natasha Gaudreault ◽  
Bonto Faburay ◽  
Jessie Trujillo ◽  
...  
Keyword(s):  
Experimental Infection ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
Valley Fever

scholarly journals Competency of Amphibians and Reptiles and Their Potential Role as Reservoir Hosts for Rift Valley Fever Virus

Viruses ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1206
Author(s):  
Melanie Rissmann ◽  
Nils Kley ◽  
Reiner Ulrich ◽  
Franziska Stoek ◽  
Anne Balkema-Buschmann ◽  
...  
Keyword(s):  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Valley Fever ◽  
Virus Shedding ◽  
Viral Loads ◽  
Field Investigations ◽  
Virus Genomes ◽  
Reservoir Hosts

Rift Valley fever phlebovirus (RVFV) is an arthropod-borne zoonotic pathogen, which is endemic in Africa, causing large epidemics, characterized by severe diseases in ruminants but also in humans. As in vitro and field investigations proposed amphibians and reptiles to potentially play a role in the enzootic amplification of the virus, we experimentally infected African common toads and common agamas with two RVFV strains. Lymph or sera, as well as oral, cutaneous and anal swabs were collected from the challenged animals to investigate seroconversion, viremia and virus shedding. Furthermore, groups of animals were euthanized 3, 10 and 21 days post-infection (dpi) to examine viral loads in different tissues during the infection. Our data show for the first time that toads are refractory to RVFV infection, showing neither seroconversion, viremia, shedding nor tissue manifestation. In contrast, all agamas challenged with the RVFV strain ZH501 carried virus genomes in the spleens at 3 dpi, but the animals displayed neither viremia nor virus shedding. In conclusion, the results of this study indicate that amphibians are not susceptible and reptiles are only susceptible to a low extent to RVFV, indicating that both species play, if at all, rather a subordinate role in the RVF virus ecology.

Experimental Infection of Young Adult European Breed Sheep with Rift Valley Fever Virus Field Isolates

2010 ◽  
Vol 10 (7) ◽  
pp. 689-696 ◽  
Author(s):  
Nuria Busquets ◽  
F. Xavier ◽  
Raquel Martín-Folgar ◽  
Gema Lorenzo ◽  
Iván Galindo-Cardiel ◽  
...  
Keyword(s):  
Young Adult ◽  
Experimental Infection ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
European Breed ◽  
Valley Fever ◽  
Field Isolates ◽  
Breed Sheep
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