Interaction Studies of Multiple Binding Sites on M4 Muscarinic Acetylcholine Receptors

Interaction Studies ◽

Multiple Binding Sites ◽

Multiple agonist binding sites of muscarinic acetylcholine receptors and their relation to the negative inotropic action of agonists in guinea-pig heart

European Journal of Pharmacology ◽

10.1016/0014-2999(85)90293-6 ◽

1985 ◽

Vol 119 (3) ◽

pp. 177-182 ◽

Cited By ~ 9

Author(s):

Atsushi Mizushima ◽

Shuji Uchida ◽

Kazuo Matsumoto ◽

Takeshi Osugi ◽

Toshifumi Kagiya ◽

...

Keyword(s):

Guinea Pig ◽

Binding Sites ◽

Acetylcholine Receptors ◽

Agonist Binding ◽

Inotropic Action ◽

Guinea Pig Heart ◽

Muscarinic Acetylcholine

Allosteric Binding Sites on Muscarinic Acetylcholine Receptors

Molecular Pharmacology ◽

10.1124/mol.105.019141 ◽

2005 ◽

Vol 68 (6) ◽

pp. 1506-1509 ◽

Cited By ~ 41

Author(s):

Jürgen Wess

Keyword(s):

Binding Sites ◽

Acetylcholine Receptors ◽

Allosteric Binding Sites

The development of novel polypharmacological agents targeting the multiple binding sites of nicotinic acetylcholine receptors

Expert Opinion on Drug Discovery ◽

10.1080/17460441.2016.1227317 ◽

2016 ◽

Vol 11 (10) ◽

pp. 969-981 ◽

Cited By ~ 4

Author(s):

Miguel Reyes-Parada ◽

Patricio Iturriaga-Vasquez

Keyword(s):

Nicotinic Acetylcholine Receptors ◽

Binding Sites ◽

Acetylcholine Receptors ◽

Nicotinic Acetylcholine ◽

Multiple Binding Sites ◽

Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.93.16.8705 ◽

1996 ◽

Vol 93 (16) ◽

pp. 8705-8709 ◽

Cited By ~ 79

Author(s):

J. Jakubik ◽

L. Bacakova ◽

V. Lisa ◽

E. E. el-Fakahany ◽

S. Tucek

Keyword(s):

Binding Sites ◽

Acetylcholine Receptors ◽

Allosteric Binding Sites

Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy

Pharmacological Research ◽

10.1016/j.phrs.2015.08.018 ◽

2015 ◽

Vol 101 ◽

pp. 9-17 ◽

Cited By ~ 14

Author(s):

Patricio Iturriaga-Vásquez ◽

Jans Alzate-Morales ◽

Isabel Bermudez ◽

Rodrigo Varas ◽

Miguel Reyes-Parada

Keyword(s):

Nicotinic Acetylcholine Receptors ◽

Binding Sites ◽

Acetylcholine Receptors ◽

Nicotinic Acetylcholine ◽

Multiple Binding Sites ◽

Messenger RNA Levels and Binding Sites of Muscarinic Acetylcholine Receptors in Gastrointestinal Muscle Layers from Healthy Dairy Cows

Journal of Receptors and Signal Transduction ◽

10.1080/10799890701417741 ◽

2007 ◽

Vol 27 (2-3) ◽

pp. 147-166 ◽

Cited By ~ 10

Author(s):

E. C. ONTSOUKA ◽

R. M. BRUCKMAIER ◽

A. STEINER ◽

J. W. BLUM ◽

M. MEYLAN

Keyword(s):

Dairy Cows ◽

Binding Sites ◽

Messenger Rna ◽

Acetylcholine Receptors ◽

Rna Levels

Effects on guanine nucleotide and sulfhydryl reagent on subpopulations of muscarinic acetylcholine receptors in mammalian hearts: Possible evidence for interconversion of super-high and low affinity agonist binding sites

European Journal of Pharmacology ◽

10.1016/0014-2999(84)90005-0 ◽

1984 ◽

Vol 100 (3-4) ◽

pp. 291-298 ◽

Cited By ~ 36

Author(s):

Shuji Uchida ◽

Kazuo Matsumoto ◽

Atsushi Mizushima ◽

Takeshi Osugi ◽

Hiroshi Higuchi ◽

...

Keyword(s):

Binding Sites ◽

Acetylcholine Receptors ◽

Guanine Nucleotide ◽

Agonist Binding ◽

Sulfhydryl Reagent

Multiple binding states of muscarinic acetylcholine receptors in membranes from neuroblastoma X glioma hybrid cells

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(80)90596-3 ◽

1980 ◽

Vol 93 (4) ◽

pp. 1058-1066 ◽

Cited By ~ 22

Author(s):

William L. Klein

Keyword(s):

Acetylcholine Receptors ◽

Hybrid Cells ◽

Molecular Biology of Muscarinic Acetylcholine Receptors

Critical Reviews in Neurobiology ◽

10.1615/critrevneurobiol.v10.i1.40 ◽

1996 ◽

Vol 10 (1) ◽

pp. 69-99 ◽

Cited By ~ 350

Author(s):

Jurgen Wess

Keyword(s):

Molecular Biology ◽

Acetylcholine Receptors ◽

Muscarinic Acetylcholine

Faculty Opinions recommendation of Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5804956.5786054 ◽

2010 ◽

Author(s):

Edward Bertaccini

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Binding Sites ◽

Transmembrane Domain ◽

General Anesthetic ◽

Nicotinic Acetylcholine ◽

Multiple Binding Sites ◽