Study of spatial organization of chicken α-globin gene domain by 3c technique

2008 ◽  
Vol 73 (11) ◽  
pp. 1192-1199 ◽  
Author(s):  
A. A. Gavrilov ◽  
S. V. Razin
Keyword(s):  
Spatial Organization ◽  
Globin Gene ◽  
Globin Gene Domain

Spatial Organization of the Chicken α-Globin Gene Domain in Cells of Different Origins

2005 ◽  
Vol 39 (6) ◽  
pp. 851-856
Author(s):  
E. S. Ioudinkova ◽  
A. V. Petrov ◽  
Y. S. Vassetzky ◽  
S. V. Razin
Keyword(s):  
Spatial Organization ◽  
Globin Gene ◽  
Different Origins ◽  
Globin Gene Domain ◽  
In Cells

scholarly journals The upstream area of the chicken α-globin gene domain is transcribed in both directions in the same cells

FEBS Letters ◽  
2005 ◽  
Vol 579 (21) ◽  
pp. 4746-4750 ◽  
Author(s):  
Victoria Borunova ◽  
Olga V. Iarovaia ◽  
Yegor S. Vassetzky ◽  
Sergey V. Razin
Keyword(s):  
Globin Gene ◽  
Globin Gene Domain

The coordinate replication of the human beta-globin gene domain reflects its transcriptional activity and nuclease hypersensitivity

1988 ◽  
Vol 8 (11) ◽  
pp. 4958-4965
Author(s):  
V Dhar ◽  
D Mager ◽  
A Iqbal ◽  
C L Schildkraut
Keyword(s):  
Cell Lines ◽  
Dna Sequences ◽  
Globin Gene ◽  
K562 Cells ◽  
Globin Genes ◽  
Beta Globin ◽  
Beta Globin Gene ◽  
Hypersensitive Sites ◽  
Flanking Sequences ◽  
Globin Gene Domain

The temporal order of replication of DNA sequences in the chromosomal domain containing the human beta-globin gene cluster and its flanking sequences (140 kilobases) was measured and compared in two different human cell lines. In human erythroleukemia (K562) cells, in which embryonic and fetal globin genes are transcribed, all of the sequences we examined from the beta-globin domain replicated early during S phase, while in HeLa cells, in which globin genes are transcriptionally silent, these sequences replicated late during S. Potential sites of initiation of DNA replication within this domain were identified. The beta-globin gene domain was also found to differ with respect to the nuclease sensitivity of the chromatin in these two cell lines. In K562 cells, hypersensitive sites for endogenous nucleases and DNase I were present in the chromatin near the earliest-replicating segments in the beta-globin domain.

scholarly journals The "beta-like-globin" gene domain in human erythroid cells.

1985 ◽  
Vol 82 (19) ◽  
pp. 6384-6388 ◽  
Author(s):  
D. Tuan ◽  
W. Solomon ◽  
Q. Li ◽  
I. M. London
Keyword(s):  
Globin Gene ◽  
Erythroid Cells ◽  
Globin Gene Domain

Detection of complementary transcripts for the intergenic region of the chicken α-globin gene domain

2015 ◽  
Vol 49 (6) ◽  
pp. 899-903
Author(s):  
E. S. Ioudinkova ◽  
A. V. Nefedochkina ◽  
O. V. Iarovaia ◽  
S. V. Razin
Keyword(s):  
Intergenic Region ◽  
Globin Gene ◽  
Globin Gene Domain
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