The Sigma-1 Receptor Ligands Chlorpromazine and Trifluoperazine Inhibit Na+ Transport in Frog Skin Epithelium

BIOPHYSICS ◽  
2020 ◽  
Vol 65 (5) ◽  
pp. 784-787
Author(s):  
A. V. Melnitskaya ◽  
Z. I. Krutetskaya ◽  
V. G. Antonov ◽  
N. I. Krutetskaya
Keyword(s):  
Frog Skin ◽  
Receptor Ligands ◽  
Na Transport ◽  
Sigma 1 Receptor ◽  
Skin Epithelium ◽  
Frog Skin Epithelium ◽  
Sigma 1

scholarly journals Sigma-1 receptor antagonists haloperidol and chlorpromazine modulate the effect of glutoxim on NA+ transport in frog skin

2019 ◽  
Vol 484 (5) ◽  
pp. 629-632
Author(s):  
Z. I. Krutetskaya ◽  
A. V. Melnitskaya ◽  
V. G. Antonov ◽  
A. D. Nozdrachev
Keyword(s):  
Voltage Clamp ◽  
Frog Skin ◽  
Na Transport ◽  
Receptor Antagonists ◽  
Sigma 1 Receptor ◽  
Voltage Clamp Technique ◽  
Frog Skin Epithelium ◽  
Sigma 1 ◽  
Immunomodulatory Drug ◽  
First Time

Using voltage-clamp technique, the involvement of sigma-1 receptors in immunomodulatory drug glutoxim regulation of Na+ transport in frog skin was investigated. We have shown for the first time that preincubation of the frog skin with sigma-1 receptor antagonists – haloperidol or chlorpromazine – attenuates the stimulatory effect of glutoxim on Na+ transport. The results suggest the possible involvement of the sigma-1 receptors in glutoxim effect on Na+transport in frog skin epithelium.

Coupling of volume and Na+ transport in frog skin epithelium

1989 ◽  
Vol 66 (1-2) ◽  
pp. 183-190 ◽  
Author(s):  
Cherng-Shing R. Tang ◽  
Kim Peterson-Yantorno ◽  
Mortimer M. Civan
Keyword(s):  
Frog Skin ◽  
Na Transport ◽  
Skin Epithelium ◽  
Frog Skin Epithelium

Lipoxygenases modulate the effect of glutoxim on Na+ transport in the frog skin epithelium

2017 ◽  
Vol 474 (1) ◽  
pp. 193-195 ◽  
Author(s):  
Z. I. Krutetskaya ◽  
A. V. Melnitskaya ◽  
V. G. Antonov ◽  
A. D. Nozdrachev
Keyword(s):  
Frog Skin ◽  
Na Transport ◽  
Skin Epithelium ◽  
Frog Skin Epithelium

scholarly journals ANALGETIC TRAMADOL MODULATES Na+ TRANSPORT IN THE FROG SKIN EPITHELIUM

2021 ◽  
Author(s):  
Anastasiya Melnitskaya ◽  
Zoya Krutetskaya ◽  
Victor Antonov ◽  
Nina Krutetskaya ◽  
Valentina Badulina
Keyword(s):  
Frog Skin ◽  
Na Transport ◽  
Skin Epithelium ◽  
Frog Skin Epithelium

Sigma-1 Receptor Antagonists Haloperidol and Chlorpromazine Modulate the Effect of Glutoxim on Na+ Transport in Frog Skin

2019 ◽  
Vol 484 (1) ◽  
pp. 63-65
Author(s):  
Z. I. Krutetskaya ◽  
A. V. Melnitskaya ◽  
V. G. Antonov ◽  
A. D. Nozdrachev
Keyword(s):  
Frog Skin ◽  
Na Transport ◽  
Receptor Antagonists ◽  
Sigma 1 Receptor ◽  
Sigma 1
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