scholarly journals Pulsatile ocular blood flow: the effect of the Valsalva manoeuvre in open angle and normal tension glaucoma: a case report and prospective study

2002 ◽  
Vol 86 (10) ◽  
pp. 1089-1092 ◽  
Author(s):  
J C Khan
Keyword(s):  
Blood Flow ◽  
Case Report ◽  
Prospective Study ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Valsalva Manoeuvre ◽  
Open Angle ◽  
Pulsatile Ocular Blood Flow

scholarly journals Effect of latanoprost 0.005% and brimonidine tartrate 0.2% on pulsatile ocular blood flow in normal tension glaucoma

2002 ◽  
Vol 86 (11) ◽  
pp. 1236-1239 ◽  
Author(s):  
C J.-L. Liu ◽  
Y-C Ko ◽  
C-Y Cheng ◽  
J C Chou ◽  
W-M Hsu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Pulsatile Ocular Blood Flow ◽  
Brimonidine Tartrate

Pulsatile ocular blood flow in primary open-angle glaucoma and ocular hypertension

2003 ◽  
Vol 136 (6) ◽  
pp. 1106-1113 ◽  
Author(s):  
Jan Kerr ◽  
Patricia Nelson ◽  
Colm O'Brien
Keyword(s):  
Blood Flow ◽  
Ocular Hypertension ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Ocular Blood Flow ◽  
Open Angle ◽  
Pulsatile Ocular Blood Flow

Four Years Later: A Clinical Update on Latanoprost

2003 ◽  
Vol 13 (2) ◽  
pp. 162-175 ◽  
Author(s):  
E. Ravinet ◽  
A. Mermoud ◽  
R. Brignoli
Keyword(s):  
Blood Flow ◽  
Open Angle Glaucoma ◽  
Cataract Extraction ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Ciliary Muscle ◽  
Angle Closure ◽  
Pigmentary Glaucoma ◽  
Long Term Treatment ◽  
Pulsatile Ocular Blood Flow

Purpose Almost five years have elapsed since the introduction of latanoprost on several markets and considering the large number of publications dealing with it, the authors felt that it was worth re-evaluating the drug. Methods The criterion used to select trials for inclusion in the review was: all articles mentioning the drug in common electronic data-bases; these were then screened and considered, on the basis of methodological quality. Results Experimental data suggest that latanoprost acts by remodeling the extracellular matrix in the ciliary muscle, thus increasing the flow of aqueous humor through the ciliary muscle bundles of the uveoscleral pathway. POAG Latanoprost persistently improves the pulsatile ocular blood flow in primary open angle glaucoma (POAG). Recent trials confirmed the greater IOP-lowering efficacy of latanoprost vs. timolol, dorzolamide, brimonidine and unoprostone. Trials lasting up to 24 months showed that latanoprost is effective in long-term treatment of POAG and ocular hypertension (OH), with no signs of loss of efficacy when compared to timolol or dorzolamide. Latanoprost provides better control of circadian IOP. Non-responders to b-blockers should preferably be switched to latanoprost monotherapy before a combination therapy is started. The possibility of a fixed combination of latanoprost and timolol has been explored, with promising results. NTG Latanoprost is effective in normal tension glaucoma (NTG), lowering IOP, improving pulsatile ocular blood flow and increasing ocular perfusion pressure. Other Glaucomas Latanoprost may provide effective IOP control in angle-closure glaucoma after iridectomy, in pigmentary glaucoma, glaucoma after cataract extraction and steroid-induced glaucoma. However, latanoprost was effective in only a minority of pediatric cases of glaucoma and is contraindicated in all forms of uveitic glaucoma. Safety In the articles reviewed, new or duration-related adverse events were reported.

Evaluation of Pulsatile Ocular Blood Flow in Primary Open-Angle Glaucoma: Trabeculectomy vs Medical Therapy

2003 ◽  
Vol 35 (1) ◽  
pp. 53-56
Author(s):  
Harish C. Agarwal ◽  
Viney Gupta ◽  
Ramanjit Sihota
Keyword(s):  
Blood Flow ◽  
Medical Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Ocular Blood Flow ◽  
Open Angle ◽  
Pulsatile Ocular Blood Flow
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