scholarly journals Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Yara A. Alnashwan ◽  
Khaled A. H. Ali ◽  
Samir S. Amr
Keyword(s):  
Abdominal Wall ◽  
Poor Prognosis ◽  
Granular Cell Tumor ◽  
Anterior Abdominal Wall ◽  
Granular Cell ◽  
Cell Tumor ◽  
Prolonged Survival ◽  
Review Of The Literature ◽  
Malignant Granular Cell Tumor ◽  
The Right

Malignant granular cell tumor (MGCT) is a rare high-grade mesenchymal tumor of Schwann cell origin. MGCTs commonly affect thigh, extremity, and trunk; however, involvement of the abdominal wall is quite rare. It has poor prognosis with 39% mortality rate in 3-year interval. We report a 50-year-old female who had MGCT arising in the anterior abdominal wall and developed massive metastatic deposits in both lungs and in the right inguinal lymph nodes, with prolonged survival for 11 years. A brief review of the literature is presented.

scholarly journals Granular-cell tumor of the anterior abdominal wall

2012 ◽  
Vol 7 (3) ◽  
pp. 716 ◽  
Author(s):  
Lee J. McGhan ◽  
Nabil Wasif ◽  
Scott W. Young ◽  
Joseph M. Collins ◽  
Ann E. McCullough
Keyword(s):  
Abdominal Wall ◽  
Granular Cell Tumor ◽  
Anterior Abdominal Wall ◽  
Granular Cell ◽  
Cell Tumor

scholarly journals Pazopanib monotherapy in a patient with a malignant granular cell tumor originating from the right orbit: A case report

2015 ◽  
Vol 10 (2) ◽  
pp. 972-974 ◽  
Author(s):  
SACHI MORITA ◽  
MARIKO HIRAMATSU ◽  
MIHOKO SUGISHITA ◽  
BISHAL GYAWALI ◽  
TAKASHI SHIBATA ◽  
...  
Keyword(s):  
Case Report ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Malignant Granular Cell Tumor ◽  
The Right

Malignant granular cell tumor: Report of a case and review of the literature

1998 ◽  
Vol 194 (7) ◽  
pp. 507-513 ◽  
Author(s):  
Hiroshi Sonobe ◽  
Jun Iwata ◽  
Mutsuo Furihata ◽  
Toshiaki Moriki ◽  
Yuji Ohtsuki
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Malignant Granular Cell Tumor

scholarly journals Malignant granular cell tumor of the ulnar nerve: A case report of long-term follow-up and literature review

2021 ◽  
Vol 8 (1) ◽  
pp. 27
Author(s):  
Sei Morinaga ◽  
Norio Yamamoto ◽  
Katsuhiro Hayashi ◽  
Akihiko Takeuchi ◽  
Shinji Miwa ◽  
...  
Keyword(s):  
Ulnar Nerve ◽  
Poor Prognosis ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Soft Tissue Tumors ◽  
Cell Tumor ◽  
Ki 67 ◽  
S 100 ◽  
Long Term Follow Up ◽  
Malignant Granular Cell Tumor

Background: The incidence of malignant granular cell tumor, an extremely rare Schwann cell-derived tumor with a poor prognosis, is reported to be approximately 0.2% of malignant soft tissue tumors. We report a case of a malignant granular cell tumor originating from the ulnar nerve.Case presentation: A 71-year-old woman presented with a mass in her right forearm. Magnetic resonance imaging showed a tumor with homogenous intensity of T1 and heterogeneous hyperintensity of T2, continuous with the ulnar nerve. Incisional biopsy revealed a malignant granular cell tumor, and marginal excision of the tumor was performed. Histologically, the tumor size was 9.2 cm and consisted of eosinophilic, granular polygonal to round and spindle-shaped cells, with vesicular and prominent nucleoli, and increased mitosis. Immunohistochemically, the tumor cells were positive for S-100 protein, CD68, H3K27me3, TFE3, and SOX10 and negative for smooth muscle alpha-actin, desmin, cytokeratin AE1/3, epithelial membrane antigen, and synaptophysin. The Ki-67 positivity rate was 12%. These findings were consistent with those of malignant granular cell tumors. In addition, no metastasis or recurrence was observed 15 years after the excision.Conclusion: Surgical resection is the standard treatment option. In our case, the diagnostic criteria for malignant granular cell tumors were histologically met. Patients with malignant granular cell tumors have a poor prognosis. However, no metastasis or recurrence was observed in this case 15 years after the surgery.

scholarly journals Malignant granular cell tumor with breast metastasis: A case report and review of the literature

2012 ◽  
Vol 4 (1) ◽  
pp. 63-66 ◽  
Author(s):  
JIDA CHEN ◽  
LINBO WANG ◽  
JING XU ◽  
TAO PAN ◽  
JIANGUO SHEN ◽  
...  
Keyword(s):  
Case Report ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Breast Metastasis ◽  
Malignant Granular Cell Tumor

scholarly journals A LARGE MALIGNANT GRANULAR CELL TUMOR ON THE LEFT CHEST WALL -A CASE REPORT AND REVIEW OF THE LITERATURE-

1988 ◽  
Vol 49 (5) ◽  
pp. 825-832
Author(s):  
Akiteru HAYASHI ◽  
Shigehiko KABURAGI ◽  
Kyoei NONAKA ◽  
Tadaaki SHIBA ◽  
Setsuo TAKEUCHI ◽  
...  
Keyword(s):  
Case Report ◽  
Chest Wall ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Left Chest ◽  
Malignant Granular Cell Tumor
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