scholarly journals Mixed Large Cell Neuroendocrine Carcinoma of the Ovary: Report of a Rare Case

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Ilias Galanis ◽  
Georgios Floros ◽  
Maria Sotiria Bompoula ◽  
Christophoros Theodoropoulos

LCNC (large cell neuroendocrine carcinomas) of the ovary is a rare aggressive tumor entity of the genital tract. Its pathogenesis, origin, and prognosis have not been fully elucidated, since there are a limited number of cases reported in literature. We report a case of an 80-year-old patient, who presented with a growing abdominal mass, which turned out to be a mixed LCNC/epithelial neoplasm. Although this type of tumor is rare, the continuous development of pathologoanatomy and immunohistochemistry contributes to our better knowledge and comprehension of these neoplasms.

2008 ◽  
Vol 204 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Pavel Dundr ◽  
Daniela Fischerová ◽  
Ctibor Povýšil ◽  
David Cibula

Folia Medica ◽  
2020 ◽  
Vol 62 (2) ◽  
pp. 412-417
Author(s):  
Spasimir T. Shopov ◽  
Benyamin L. Anavi ◽  
Dobrin K. Krastev

Large-cell neuroendocrine carcinoma of the endometrium is an insufficiently researched aggressive tumor with a short survival regard­less of the treatment type. We present here the 38th consecutive case of literature reported cases of large cell neuroendocrine carcinoma of the endometrium (posi­tive for synaptophysin, CD56, chromogranin A, p53, and Vimentin) found in the myomatous uterus of a 76-year-old woman. We also describe in the study the morphological algorithm for differentiation of malignant blastomas with small (under 10 %) neuro-endocrinal component. Accumulated clinical and morphological evidence raises the question whether the large-cell and the small-cell neuroendocrine carcino­mas are just different variations according to their histology and topical occurrence (uterine body/cervix) or they are just independent forms with their respective clinical signs, morphology, treatment, and prognosis.


2020 ◽  
Vol 16 (11) ◽  
pp. 760-763
Author(s):  
Chang-Hoon Lee ◽  
So-Yeon Jeon ◽  
Hyo-Seon Kim ◽  
Eun-Kee Song ◽  
Jae-Yong Kwak ◽  
...  

2020 ◽  
Vol 4 (2) ◽  
pp. 90
Author(s):  
Sana Ennouri ◽  
Jihene Feki ◽  
Syrine Sghaier ◽  
Manel Mellouli ◽  
Tahya Boudawara ◽  
...  

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