A Comparison of the Exponential Decay Slope between PEG-IFN alfa-2b/Ribavirin and IFN alfa-2b/Ribavirin Combination Therapy in Patients with Chronic Hepatitis C Genotype 1b Infection and a High Viral Load

Intervirology ◽  
2004 ◽  
Vol 47 (2) ◽  
pp. 102-107 ◽  
Author(s):  
Namiki Izumi ◽  
Yasuhiro Asahina ◽  
Masayuki Kurosaki ◽  
Masakatsu Uchihara ◽  
Yuki Nishimura ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Combination Therapy ◽  
Chronic Hepatitis C ◽  
Exponential Decay ◽  
High Viral Load ◽  
Genotype 1B

Prolonged Negative HCV-RNA Status Led to a Good Outcome in Chronic Hepatitis C Patients with Genotype 1b and Super-High Viral Load

Intervirology ◽  
2006 ◽  
Vol 49 (6) ◽  
pp. 362-369 ◽  
Author(s):  
Hiroshi Kohno ◽  
Shiomi Aimitsu ◽  
Mikiya Kitamoto ◽  
Yasuyuki Aisaka ◽  
Hiroiku Kawakami ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
High Viral Load ◽  
Hcv Rna ◽  
Good Outcome ◽  
Genotype 1B ◽  
Chronic Hepatitis C Patients

scholarly journals Response factors to pegylated interferon-alfa/ribavirin treatment in chronic hepatitis C patients genotype 1b

2014 ◽  
Vol 66 (1) ◽  
pp. 193-201 ◽  
Author(s):  
Snezana Jovanovic-Cupic ◽  
S. Glisic ◽  
M. Stanojevic ◽  
N. Vasiljevic ◽  
T. Bojic-Milinovic ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Combination Therapy ◽  
Chronic Hepatitis C ◽  
Sustained Viral Response ◽  
Therapy Response ◽  
Pegylated Interferon ◽  
Response To Therapy ◽  
Genotype 1B

Hepatitis C virus infection is the most common chronic blood-borne infection and one of the most important causes of chronic liver disease. Knowing the predictors associated with pegylated interferon/ribavirin (PEG-IFN/RBV) combination therapy response is important for evidence-based treatment recommendations. The goal of this study was to identify host and viral factors of response to PEG-IFN/RBV treatment in chronic hepatitis C genotype 1b patients. We have examined the relationship between gender, age, level of alanine aminotransferase (ALT), viral load and liver fibrosis progression on therapy response. ALT level and viral load were evaluated before starting treatment with combination therapy. The elevated levels of ALT and route of HCV transmission were found to be significantly associated with the response to therapy in HCV-infected patients. Our findings may be useful for estimating a patient?s likelihood of achieving sustained viral response.

scholarly journals Response-guided therapy in Japanese chronic hepatitis C patients infected with genotype 1b and high viral load

Kanzo ◽  
2009 ◽  
Vol 50 (12) ◽  
pp. 687-702
Author(s):  
Noritomo Shimada ◽  
Kai Yoshizawa ◽  
Makiko Ika ◽  
Akira Dobashi ◽  
Naoto Nomura ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
High Viral Load ◽  
Genotype 1B ◽  
Chronic Hepatitis C Patients ◽  
Guided Therapy

Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 1b and high viral load

2012 ◽  
Vol 42 (10) ◽  
pp. 949-957 ◽  
Author(s):  
Yasuji Arase ◽  
Yusuke Kawamura ◽  
Yoshiyuki Suzuki ◽  
Fumitaka Suzuki ◽  
Norio Akuta ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Elderly Patients ◽  
Chronic Hepatitis C ◽  
High Viral Load ◽  
Genotype 1B

scholarly journals Acute Pancreatitis Associated with Pegylated Interferon and Ribavirin Treatment of Chronic Hepatitis C, Genotype 1b with High Viral Load

2009 ◽  
Vol 3 (3) ◽  
pp. 372-376 ◽  
Author(s):  
Kenji Ando ◽  
Soo Ryang Kim ◽  
Susumu Imoto ◽  
Taisuke Nakajima ◽  
Keiji Mita ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Chronic Hepatitis ◽  
Viral Load ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Pegylated Interferon ◽  
High Viral Load ◽  
Genotype 1B
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