Primitive Neuroectodermal Tumor Arising from Testicular Teratoma with Metastases: A Case Report of a Rare Germ Cell Tumor with Poor Prognosis

2009 ◽  
Vol 3 (4) ◽  
pp. 207-209
Author(s):  
Eric Z. Massanyi ◽  
Randy G. Allison ◽  
Raymond E. Clarke ◽  
Kevin A. Spear
Keyword(s):  
Case Report ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Poor Prognosis ◽  
Primitive Neuroectodermal Tumor ◽  
Cell Tumor ◽  
Neuroectodermal Tumor

scholarly journals Response to 5-Fluorouracil-Based Chemotherapy in a Patient with Metastatic Colonic-Type Adenocarcinoma Arising in a Primary Mediastinal Teratoma

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Arunee Dechaphunkul ◽  
Gilbert Bigras ◽  
Michael Sawyer
Keyword(s):  
Germ Cell ◽  
Malignant Transformation ◽  
Germ Cell Tumor ◽  
Primitive Neuroectodermal Tumor ◽  
Chemotherapy Regimen ◽  
Cell Tumor ◽  
Neuroectodermal Tumor ◽  
Mediastinal Teratoma ◽  
First Case ◽  
Localized Disease

Germ cell tumor with somatic malignant transformation is an uncommon phenomenon occurring about 7% of all mediastinal teratomas. Among all transformed component, sarcoma appears to be the most frequent histology, followed by primitive neuroectodermal tumor (PNET) and adenocarcinoma. To our knowledge, there were 3 cases of colonic-type adenocarcinoma arising in a primary teratoma have been reported to date. However, none of them received chemotherapy directed to transformed histology given localized disease at presentation. We, therefore, report here the first case of patient who achieved good response from chemotherapy directed to transformed histology, which confirms the importance of chemotherapy regimen used.

Primitive Neuroectodermal Tumor (PNET) as Somatic-Type Malignancy Arising from an Extragonadal Germ-Cell Tumor: Clinical, Pathological and Molecular Features of a Case

2013 ◽  
Vol 99 (1) ◽  
pp. e24-e27 ◽  
Author(s):  
Amit Garg ◽  
Ayoub Nahal ◽  
Robert Turcotte ◽  
Roger Tabah ◽  
Thierry Alcindor
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Primitive Neuroectodermal Tumor ◽  
Cell Tumor ◽  
Neuroectodermal Tumor ◽  
Chromosome 22 ◽  
Round Cell ◽  
Molecular Features ◽  
Nonseminomatous Germ Cell Tumor ◽  
Axillary Mass

We report a rare case of a 34-year-old man with a right axillary mass. Ten years previously, he had been diagnosed with a right scapular nonseminomatous germ-cell tumor consisting of teratoma, completely resected without any further treatment. Presently he was found to have a metastatic malignant small round cell tumor consistent with a secondary somatic malignancy arising in the background of nonseminomatous germ-cell tumor, teratoma, yolk sac tumor, and primitive neuroectodermal tumor with distinct chromosome 22 translocation. Although the patient initially responded well to chemotherapy with etoposide, cisplatin, ifosfamide and mesna, he relapsed shortly after.

Suprasellar Mixed Germ Cell Tumor: Case Report

2003 ◽  
Vol 48 (1) ◽  
pp. 95
Author(s):  
Eun Ja Lee ◽  
Hye Kyung Lee ◽  
Mi Sung Kim
Keyword(s):  
Case Report ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Cell Tumor ◽  
Mixed Germ Cell Tumor
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