IgE Antibody Responses in vitro: from Rodents to Man

2015 ◽  
pp. 105-160
Author(s):  
David H. Katz
Keyword(s):  
Antibody Responses ◽  
Ige Antibody

Suppression of IgE antibody responses by NKT cells—mechanisms of NKT cell-mediated regulatory function

2005 ◽  
Vol 1285 ◽  
pp. 179-183
Author(s):  
Satoshi Kojo ◽  
Michishige Harada ◽  
Ken-ichiro Seino ◽  
Masaru Taniguchi
Keyword(s):  
Nkt Cells ◽  
Antibody Responses ◽  
Regulatory Function ◽  
Nkt Cell ◽  
Ige Antibody

scholarly journals Induction of a ragweed-specific allergic state in Ir-gene-restricted nonresponder mice.

1977 ◽  
Vol 146 (1) ◽  
pp. 302-307 ◽  
Author(s):  
N Chiorazzi ◽  
A S Tung ◽  
D H Katz
Keyword(s):  
Inbred Mice ◽  
Inbred Strains ◽  
Antibody Responses ◽  
Pollen Extract ◽  
Antibody Synthesis ◽  
Ige Antibody ◽  
Gene Concept ◽  
X Irradiation ◽  
Suppressive Mechanism ◽  
Ir Genes

Mice of the inbred strains, C57BL/6 and C57BL/10 (H-2b), are genetically incapable of developing IgE antibody responses to ragweed pollen extract (RE) or its dinitrophenylated derivative, DNP-RE. This nonresponsiveness has previously been thought to reflect the absence of a relevant H-2-linked Ir genes controlling responses of inbred mice to these antigens. However, pretreatment of H-2b mice with either low doses of ionizing X irradiation or cyclophosphamide abrogates the nonresponder status of such animals, apparently by removal of a suppressive mechanism normally inhibiting development of IgE responses to these antigens. The implications of these findings for mechanisms of genetic control of IgE antibody synthesis and the Ir-gene concept are discussed.

Macrolidic antibiotics: Effects on primary in vitro antibody responses

1988 ◽  
Vol 10 (8) ◽  
pp. 919-924 ◽  
Author(s):  
Maria L. Villa ◽  
Francesca Valenti ◽  
Marina Mantovani ◽  
Franco Scaglione ◽  
Enrico Clerici
Keyword(s):  
Antibody Responses
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