Real-Time Biospecific Interaction Analysis of Immobilized Interleukin-2 Receptor β-Chain Peptides with Polyclonal Antibodies1

1994 ◽  
pp. 243-250
Author(s):  
K. Schmitt ◽  
U. Schwuléra ◽  
I. Amiri ◽  
U. Roder ◽  
Å. Edström ◽  
...  
Keyword(s):  
Real Time ◽  
Interaction Analysis ◽  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Biospecific Interaction ◽  
Β Chain

Transcriptional regulation of the mouse interleukin-2 receptor β chain gene by Ets and Egr-1

2005 ◽  
Vol 329 (3) ◽  
pp. 1094-1101 ◽  
Author(s):  
Sang-Kyu Ye ◽  
Tack Joong Kim ◽  
Sung Sik Won ◽  
Taek Joon Yoon ◽  
Tae Kyu Park ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Interleukin 2 ◽  
Chain Gene ◽  
Interleukin 2 Receptor ◽  
Β Chain

scholarly journals Interleukin-2 Receptor β-Chain (p70-75) Expressed on Leukemic Cells from Adult T Cell Leukemia Patients

1990 ◽  
Vol 81 (9) ◽  
pp. 902-908 ◽  
Author(s):  
Taiichi Kodaka ◽  
Takashi Uchiyama ◽  
Takayuki Ishikawa ◽  
Masanori Kamio ◽  
Rie Onishi ◽  
...  
Keyword(s):  
T Cell ◽  
Interleukin 2 ◽  
Leukemic Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Interleukin 2 Receptor ◽  
Β Chain

Assignment of the interleukin-2 receptor β chain gene (II-2rb) to band E on mouse chromosome 15

Genomics ◽  
1992 ◽  
Vol 12 (1) ◽  
pp. 179-180 ◽  
Author(s):  
Hugh D. Campbell ◽  
Graham C. Webb ◽  
Takeshi Kono ◽  
Tadatsugu Taniguchi ◽  
Judith H. Ford ◽  
...  
Keyword(s):  
Mouse Chromosome ◽  
Interleukin 2 ◽  
Chain Gene ◽  
Chromosome 15 ◽  
Interleukin 2 Receptor ◽  
Β Chain

Endocytosis of the β chain of interleukin-2 receptor requires neither interleukin-2 nor the γ chain

1994 ◽  
Vol 24 (9) ◽  
pp. 1951-1955 ◽  
Author(s):  
Agnès Hémar ◽  
Michéle Lieb ◽  
Agathe Subtil ◽  
James P. Disanto ◽  
Alice Dautry-Varsat
Keyword(s):  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Β Chain

Synthetic Peptides from the Region 30-54 of the Interleukin-2 Receptor β-Chain (IL-2Rβ)Affect IL-2 Binding to Human T-Cells

1994 ◽  
Vol 59 (4) ◽  
pp. 943-950
Author(s):  
Eugenia Drakopoulou ◽  
Georgia Sotiropoulou ◽  
Vassilis Tsilivakos ◽  
Vassilis Georgoulias ◽  
Paul Cordopatis
Keyword(s):  
Synthetic Peptides ◽  
Biological Effect ◽  
Active Sites ◽  
Interleukin 2 ◽  
Interleukin 2 Receptor ◽  
Equilibrium Binding ◽  
Extracellular Region ◽  
Human T Cells ◽  
Receptor Interactions ◽  
Β Chain

The interleukin-2 receptor β-chain (IL-2Rβ) is responsible for the IL-2 internalization and signal transduction. To identify domains from the IL-2Rβ extracellular region which are involved in ligand receptor interactions, eight peptides of 8 to 25 amino acids corresponding to IL-2Rβ sequence 30-54 were synthesized. Their biological effect was tested with [125I]IL-2 equilibrium binding to PHA-blasts. Preincubation of [125I]IL-2 with peptides IL-2Rβ (35-54) and (30-42) affects IL-2 binding to both high and intermediate affinity receptors by revealing a greater number of active sites with lower affinity.

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