Recurrent Prostatic Stromal Tumor of Uncertain Malignant Potential Combined with Concurrent Prostatic Adenocarcinoma: An Unusual Case

2021 ◽  
pp. 1-5
Author(s):  
Zhen Zhang ◽  
Chaozhao Liang
Keyword(s):  
Transurethral Resection ◽  
Unusual Case ◽  
Malignant Potential ◽  
Prostatic Adenocarcinoma ◽  
Stromal Tumor ◽  
Simultaneous Occurrence ◽  
Uncertain Malignant Potential ◽  
Unique Case ◽  
Neoplastic Lesions

Prostatic stromal tumor of uncertain malignant potential (STUMP), characterized by an atypical, unique stromal proliferation of the prostate, is often difficult to be differentiated from other nonepithelial neoplastic lesions. We present a unique case of recurrent STUMP after transurethral resection of the prostate (TURP) with concurrent prostatic adenocarcinoma. Patients diagnosed with prostatic STUMP should be followed up closely, for it may recur and invade adjacent organs after TURP shortly. Concurrent prostatic adenocarcinoma can be found in STUMP patients, and there may be some potential mechanisms which promote the simultaneous occurrence of the 2 tumors.

scholarly journals Prostatic Stromal Tumor of Uncertain Malignant Potential Which Was Difficult to Diagnose

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Satoko Matsuyama ◽  
Takahiro Nohara ◽  
Shohei Kawaguchi ◽  
Chikashi Seto ◽  
Yuko Nakanishi ◽  
...  
Keyword(s):  
Transurethral Resection ◽  
Digital Rectal Examination ◽  
Radical Resection ◽  
Final Diagnosis ◽  
Malignant Potential ◽  
Stromal Tumor ◽  
Prostatic Urethra ◽  
Uncertain Malignant Potential ◽  
Stromal Sarcoma ◽  
Stromal Tissue

Here, we report a case of stromal tumor of uncertain malignant potential (STUMP) that was difficult to diagnose. A 53-year-old male was found to have a hard nodule on digital rectal examination; magnetic resonance imaging revealed a large nodule on the left side of the prostate, indicating prostate cancer. However, pathological diagnosis of the biopsy specimen was benign prostatic hyperplasia. Although a papillary tumor in the prostatic urethra was also seen on urethrocystoscopy, the tumor specimen obtained from transurethral resection was not malignant. The tumor in the prostatic urethra recurred only 3 months after transurethral resection, and pathological findings revealed benign hyperplasia not only in the stromal tissue but also in the epithelium; therefore, the prostate tumor was suspected to be STUMP. It took many prostate pathologists a long time to reach the final diagnosis of STUMP. STUMP is a rare benign tumor, difficult to diagnose, and sometimes transforms into stromal sarcoma. Thus, we should consider radical resection in such cases.

Prostatic Stromal Tumor of Uncertain Malignant Potential

2019 ◽  
pp. 1-3
Author(s):  
Alessia Cimadamore ◽  
Liang Cheng ◽  
Rodolfo Montironi
Keyword(s):  
Malignant Potential ◽  
Stromal Tumor ◽  
Uncertain Malignant Potential

Prostatic stromal tumor of uncertain malignant potential (STUMP) with unrecognized growth pattern

2011 ◽  
Vol 62 (1) ◽  
pp. 69-71
Author(s):  
Soichiro Fushimi ◽  
Tetsuya Ogino ◽  
Ken Aoki ◽  
Junya Itakura ◽  
Toshihiro Ito ◽  
...  
Keyword(s):  
Growth Pattern ◽  
Malignant Potential ◽  
Stromal Tumor ◽  
Uncertain Malignant Potential

Incidental Prostatic Stromal Tumor of Uncertain Malignant Potential (STUMP): Histopathological and Immunohistochemical Findings

2012 ◽  
Vol 79 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Ettore De Berardinis ◽  
Gian Maria Busetto ◽  
Gabriele Antonini ◽  
Riccardo Giovannone ◽  
Mariarosaria Di Placido ◽  
...  
Keyword(s):  
Prostate Gland ◽  
Digital Rectal Examination ◽  
Radical Retropubic Prostatectomy ◽  
Malignant Potential ◽  
Stromal Tumor ◽  
Uncertain Malignant Potential ◽  
Transperineal Prostate Biopsy ◽  
Stromal Sarcoma ◽  
Long Term Follow Up

Stromal prostate tumors are rare neoplastic proliferative lesions that have been classified into prostatic stromal tumor of uncertain malignant potential (STUMP) and prostatic stromal sarcoma (SS) based on these criteria: stromal cellularity, presence of mitotic figures, necrosis, and stromal overgrowth. A prostatic stromal tumor of uncertain malignant potential (STUMP) is a non-epithelial, mesenchymal spindle-cell tumor that can be classified as a specialized stromal tumor of the prostate. STUMPs have the capability to diffusely infiltrate the prostate gland and extend into adjacent tissues. Furthermore, they often recur and this is why they are considered as neoplastic entities. STUMPs usually tend to be not aggressive, but occasional cases have been reported with an extension into adjacent tissues. A few cases develop a sarcomatous dedifferentiation. A 67-year-old male referred to the Department of Urology, Sapienza Rome University, with acute urinary retention (AUR) and bladder overdistention. Digital rectal examination (DRE) showed the presence of a severe prostatic hyperplasia and a transvesical prostatic adenomectomy (TVPA) was performed. The pathological evaluation performed at the Department of Pathology, Sapienza Rome University, revealed an incidental diagnosis of prostatic STUMP. The patient's follow-up is made every year with transrectal ultrasonography and nuclear magnetic resonance with spectroscopy, and every two years with a transperineal prostate biopsy to exclude a progression to a stromal sarcoma. After 5 years of follow-up the STUMP is still detectable but there is no sign of sarcoma. As a result of its relative rarity and lack of long-term follow-up, the prognosis of STUMP is unclear. Therapy varies from a wait-and-see approach to a radical retropubic prostatectomy.

scholarly journals Rare and Challenging Tumor Entity: Phyllodes Tumor of the Prostate

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
Andreas Bannowsky ◽  
Andreas Probst ◽  
Helmut Dunker ◽  
Tillmann Loch
Keyword(s):  
Malignant Tumor ◽  
Transurethral Resection ◽  
Phyllodes Tumor ◽  
Malignant Potential ◽  
Histological Diagnosis ◽  
Uncertain Malignant Potential ◽  
Stromal Tumors ◽  
Stromal Sarcoma ◽  
Resection Specimen ◽  
Tumor Entity

Cystic epithelial-stromal tumors of the prostate are rare, with 82 cases reported in literature. These cases have been published under a variety of diagnoses, including phyllodes tumor and prostatic stromal proliferation of uncertain malignant potential as well as a malignant tumor called “prostatic stromal sarcoma”. We report a case of a 60-year-old man with the histological diagnosis of phyllodes tumor of the prostate in transurethral resection specimen.

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