scholarly journals Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to congenital heart defects.

Circulation ◽  
1994 ◽  
Vol 90 (3) ◽  
pp. 1287-1293 ◽  
Author(s):  
M M Brook ◽  
J R Fineman ◽  
A M Bolinger ◽  
A F Wong ◽  
M A Heymann ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects

scholarly journals Pulmonary hypertension in infants with congenital heart defects: are leukotrienes involved?

1997 ◽  
Vol 6 (5-6) ◽  
pp. 323-326 ◽  
Author(s):  
A. Serraf ◽  
J-P. Gascard ◽  
J. Bruniaux ◽  
C. Labat ◽  
C. Planche ◽  
...  
Keyword(s):  
Blood Flow ◽  
Pulmonary Hypertension ◽  
Congenital Heart Defects ◽  
Pulmonary Blood Flow ◽  
Congenital Heart ◽  
Heart Defects ◽  
Blood Levels ◽  
Blood Samples ◽  
Number Of Patients ◽  
Pulmonary Arterial

The circulating levels of leukotriene E4in infants with congenital heart defects, increased pulmonary blood flow and pulmonary arterial hypertension, were determined and compared with infants with decreased pulmonary blood flow (Tetralogy of Fallot). There was no correlation (r=0.38) between the pulmonary arterial pressure (56 ± 4 mmHg) and the leukotriene E4levels (1.37 ± 0.67 ng/ml blood) measured in peripheral blood samples from the hypertensive group prior to surgery. There was considerable variation in the detectable leukotriene E4levels in blood samples from different patients. The levels detected in the blood samples between the two groups of patients was similar. These data suggest that neither the surgical repair during cardiopulmonary bypass nor the pulmonary hypertension appeared to modify the leukotriene E4blood levels in the small number of patients studied.

scholarly journals Long-Term Prostacyclin for Pulmonary Hypertension With Associated Congenital Heart Defects

Circulation ◽  
1999 ◽  
Vol 99 (14) ◽  
pp. 1858-1865 ◽  
Author(s):  
Erika Berman Rosenzweig ◽  
Diane Kerstein ◽  
Robyn J Barst
Keyword(s):  
Pulmonary Hypertension ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects

Inhaled nitric oxide for postoperative pulmonary hypertension in patients with congenital heart defects

The Lancet ◽  
1992 ◽  
Vol 340 (8834-8835) ◽  
pp. 1545 ◽  
Author(s):  
Ayman Haydar ◽  
Philippe Mauriat ◽  
Philippe Pouard ◽  
Didier Lefèbvre ◽  
Thierry Malhere ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Hypertension ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Inhaled Nitric Oxide
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