Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1α and Upregulation of Peroxisome Proliferator–activated Receptor-α

Shouji Matsushima; Junya Kuroda; Tetsuro Ago; Peiyong Zhai; Yoshiyuki Ikeda; Shinichi Oka; Guo-Hua Fong; Rong Tian; Junichi Sadoshima

doi:10.1161/circresaha.111.300171

Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1α and Upregulation of Peroxisome Proliferator–activated Receptor-α

Circulation Research ◽

10.1161/circresaha.111.300171 ◽

2013 ◽

Vol 112 (8) ◽

pp. 1135-1149 ◽

Cited By ~ 77

Author(s):

Shouji Matsushima ◽

Junya Kuroda ◽

Tetsuro Ago ◽

Peiyong Zhai ◽

Yoshiyuki Ikeda ◽

...

Keyword(s):

Nadph Oxidase ◽

Reperfusion Injury ◽

Oxidase Activity ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Hypoxia Inducible Factor ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Nadph Oxidase Activity ◽

Hypoxia Inducible Factor 1Α

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Interactions of Hypoxia inducible factor (HIF)‐1α and Peroxisome proliferator‐activated receptor (PPAR) α in the protection against ischemia/reperfusion injury in the rat kidney

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.703.4 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Mohammad Dallatu ◽

Adebayo Oyekan

Keyword(s):

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Rat Kidney ◽

Ischemia Reperfusion ◽

Hypoxia Inducible Factor ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor

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5d, a novel analogue of 3-n-butylphthalide, decreases NADPH oxidase activity through the positive regulation of CK2 after ischemia/reperfusion injury

Oncotarget ◽

10.18632/oncotarget.8548 ◽

2016 ◽

Vol 7 (26) ◽

pp. 39444-39457 ◽

Cited By ~ 6

Author(s):

Jia Zhou ◽

Yi-hua Zhang ◽

Hui-zhu Song ◽

Hui Ji ◽

Xiao-li Wang ◽

...

Keyword(s):

Nadph Oxidase ◽

Reperfusion Injury ◽

Oxidase Activity ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Positive Regulation ◽

Nadph Oxidase Activity

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Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-γ ligand, pioglitazone, in rats

Redox Report ◽

10.1179/135100002125000983 ◽

2002 ◽

Vol 7 (5) ◽

pp. 294-299 ◽

Cited By ~ 42

Author(s):

Yuji Naito ◽

Tomohisa Takagi ◽

Kazuhiko Uchiyama ◽

Osamu Handa ◽

Naoya Tomatsuri ◽

...

Keyword(s):

Reperfusion Injury ◽

Intestinal Ischemia ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Intestinal Ischemia Reperfusion

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Monocyte Chemoattractant Protein-Induced Protein 1 Targets Hypoxia-Inducible Factor 1α to Protect Against Hepatic Ischemia/Reperfusion Injury

Hepatology ◽

10.1002/hep.30086 ◽

2018 ◽

Vol 68 (6) ◽

pp. 2359-2375 ◽

Cited By ~ 11

Author(s):

Peng Sun ◽

Yue-Xin Lu ◽

Daqing Cheng ◽

Kuo Zhang ◽

Jilin Zheng ◽

...

Keyword(s):

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Hypoxia Inducible Factor ◽

Hepatic Ischemia ◽

Monocyte Chemoattractant ◽

Hypoxia Inducible Factor 1Α ◽

Monocyte Chemoattractant Protein ◽

Hepatic Ischemia Reperfusion

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Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor

The Journal of Immunology ◽

10.4049/jimmunol.0903617 ◽

2011 ◽

Vol 186 (7) ◽

pp. 4367-4374 ◽

Cited By ~ 103

Author(s):

Melanie L. Hart ◽

Almut Grenz ◽

Iris C. Gorzolla ◽

Jens Schittenhelm ◽

Julee H. Dalton ◽

...

Keyword(s):

Reperfusion Injury ◽

Adenosine Receptor ◽

Intestinal Ischemia ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Hypoxia Inducible Factor ◽

Hypoxia Inducible Factor 1Α ◽

A2b Adenosine Receptor ◽

Intestinal Ischemia Reperfusion

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Peroxisome proliferator-activated receptor β/δ agonism protects the kidney against ischemia/reperfusion injury in diabetic rats

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2010.10.710 ◽

2011 ◽

Vol 50 (2) ◽

pp. 345-353 ◽

Cited By ~ 32

Author(s):

Massimo Collino ◽

Elisa Benetti ◽

Gianluca Miglio ◽

Sara Castiglia ◽

Arianna Carolina Rosa ◽

...

Keyword(s):

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Diabetic Rats ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor

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Study of peroxisome proliferator–activated receptor (PPAR)-γ in renal ischemia–reperfusion injury

Transplantation Proceedings ◽

10.1016/j.transproceed.2004.08.039 ◽

2004 ◽

Vol 36 (7) ◽

pp. 1946-1948 ◽

Cited By ~ 15

Author(s):

R. Yoshimura ◽

M. Matsuyama ◽

Y. Segawa ◽

K. Tsuchida ◽

Y. Takemoto ◽

...

Keyword(s):

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Renal Ischemia ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Ppar Γ ◽

Renal Ischemia Reperfusion Injury

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In Vivo Activation of Peroxisome Proliferator-Activated Receptor-δ Protects the Heart from Ischemia/Reperfusion Injury in Zucker Fatty Rats

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.107.135327 ◽

2008 ◽

Vol 325 (2) ◽

pp. 466-474 ◽

Cited By ~ 51

Author(s):

Tian-Li Yue ◽

Sandhya S. Nerurkar ◽

Weike Bao ◽

Beat M. Jucker ◽

Lea Sarov-Blat ◽

...

Keyword(s):

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor

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Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats

Pharmacology ◽

10.1159/000503727 ◽

2019 ◽

Vol 105 (3-4) ◽

pp. 231-242 ◽

Cited By ~ 1

Author(s):

Chuiliang Liu ◽

Ruiwen Ding ◽

Wujian Huang ◽

Liping Miao ◽

Junhua Li ◽

...

Keyword(s):

Reperfusion Injury ◽

Intestinal Ischemia ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Nuclear Factor Κb ◽

Peroxisome Proliferator ◽

Nuclear Factor ◽

Peroxisome Proliferator Activated Receptor ◽

Intestinal Ischemia Reperfusion

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Expression of Peroxisome Proliferator-Activated Receptor-γ in Renal Ischemia-Reperfusion Injury

Transplantation Proceedings ◽

10.1016/j.transproceed.2005.02.068 ◽

2005 ◽

Vol 37 (4) ◽

pp. 1684-1685 ◽

Cited By ~ 12

Author(s):

M. Matsuyama ◽

R. Yoshimura ◽

T. Hase ◽

J. Uchida ◽

K. Tsuchida ◽

...

Keyword(s):

Reperfusion Injury ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Renal Ischemia ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Renal Ischemia Reperfusion Injury

Download Full-text