scholarly journals Fundus Autofluorescence and Spectral-Domain Optical Coherence Tomography Characteristics in a Rapidly Progressing Form of Geographic Atrophy

2011 ◽  
Vol 52 (6) ◽  
pp. 3761 ◽  
Author(s):  
Monika Fleckenstein ◽  
Steffen Schmitz-Valckenberg ◽  
Christine Martens ◽  
Sebastian Kosanetzky ◽  
Christian K. Brinkmann ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Spectral Domain ◽  
Optical Coherence

A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Patients with Geographic Atrophy

Ophthalmology ◽  
2011 ◽  
Vol 118 (9) ◽  
pp. 1844-1851 ◽  
Author(s):  
Ramzi G. Sayegh ◽  
Christian Simader ◽  
Ulrike Scheschy ◽  
Alessio Montuoro ◽  
Christopher Kiss ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Systematic Comparison

scholarly journals Correlation between Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence at the Margins of Geographic Atrophy

2009 ◽  
Vol 148 (3) ◽  
pp. 439-444.e1 ◽  
Author(s):  
Manpreet Brar ◽  
Igor Kozak ◽  
Lingyun Cheng ◽  
Dirk-Uwe G. Bartsch ◽  
Ritchie Yuson ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Spectral Domain ◽  
Optical Coherence

A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

2014 ◽  
Vol 158 (3) ◽  
pp. 557-566.e1 ◽  
Author(s):  
Christian Simader ◽  
Ramzi G. Sayegh ◽  
Alessio Montuoro ◽  
Malek Azhary ◽  
Anna Lucia Koth ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Longitudinal Comparison

Segmentation of the Geographic Atrophy in Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence Images

2013 ◽  
Vol 54 (13) ◽  
pp. 8375 ◽  
Author(s):  
Zhihong Hu ◽  
Gerard G. Medioni ◽  
Matthias Hernandez ◽  
Amirhossein Hariri ◽  
Xiaodong Wu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Spectral Domain ◽  
Optical Coherence

scholarly journals Assessing Dry Age-Related Macular Degeneration in a Mexican Population with Fundus Autofluorescence and Spectral Domain Optical Coherence Tomography

2018 ◽  
Vol 09 (05) ◽  
Author(s):  
Renata del Carmen Garcia Franco ◽  
Marlon Rafael Garcia Roa ◽  
Veronica Romero Morales ◽  
Miguel Angel Vazquez Membrillo ◽  
Ximena Mira Lorenzo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Mexican Population ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Age Related

Tracking Progression with Spectral-Domain Optical Coherence Tomography in Geographic Atrophy Caused by Age-Related Macular Degeneration

2010 ◽  
Vol 51 (8) ◽  
pp. 3846 ◽  
Author(s):  
Monika Fleckenstein ◽  
Steffen Schmitz-Valckenberg ◽  
Christine Adrion ◽  
Irene Krämer ◽  
Nicole Eter ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Age Related

Fundus autofluorescence and spectral domain optical coherence tomography in uveitic macular edema

2009 ◽  
Vol 247 (12) ◽  
pp. 1685-1689 ◽  
Author(s):  
Martin Roesel ◽  
Andreas Henschel ◽  
Carsten Heinz ◽  
Martha Dietzel ◽  
Georg Spital ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Fundus Autofluorescence ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Uveitic Macular Edema

scholarly journals Early Detection of Incipient Retinal Pigment Epithelium Atrophy Overlying Drusen with Fundus Autofluorescence vs. Spectral Domain Optical Coherence Tomography

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Anabel Rodríguez ◽  
Marc Biarnés ◽  
Rosa M. Coco-Martin ◽  
Anna Sala-Puigdollers ◽  
Jordi Monés
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Pigment Epithelium ◽  
Median Time ◽  
Pigment Epithelium ◽  
Fundus Autofluorescence ◽  
Retinal Pigment ◽  
Geographic Atrophy ◽  
Optical Coherence ◽  
Rpe Atrophy ◽  
Sd Oct

Purpose. This study aims to find out which tool, fundus autofluorescence (FAF) or spectral domain optical coherence tomography (SD-OCT), is more sensitive in detecting retinal pigment epithelium (RPE) demise overlying drusen and can, therefore, help predict geographic atrophy (GA) appearance in Age-Related Macular Degeneration (AMD). Methods. A single-site, retrospective, observational, longitudinal study was conducted. Patients with intermediate AMD (iAMD) (large (>125 μm) or intermediate (63–125 μm) drusen with hyper/hypopigmentation) with a minimum follow-up of 18 months were included. Drusen with overlying incipient RPE atrophy were identified on SD-OCT defined as choroidal hypertransmission or nascent geographic atrophy (nGA). These selected drusen were, then, traced backwards in time to determine if incipient RPE atrophy overlying drusen was observed on FAF (well-demarcated region of absence of autofluorescence) before, simultaneously, or after having detected the first signs of incipient RPE atrophy on SD-OCT. The number of drusen in which signs of incipient RPE atrophy was detected earlier using FAF or SD-OCT was compared. The time elapsed from the identification with the more sensitive method to the other was recorded and analyzed. Results. One hundred and thirty-three drusen in 22 eyes of 22 patients were included. Of these, 112 (84.2%) drusen showed choroidal hypertransmission and 21(15.8%) nGA. Early signs of atrophy overlying drusen were found simultaneously on SD-OCT and FAF in 52 cases (39.1%, 95% CI 30.8–47.9%), earliest on FAF in 51 (38.3%, 95% CI 30.0–47.2%) and first on SD-OCT in 30 (22.6%, 95% CI 15.8–30.6%; p<0.05). Statistically significant differences were found between both techniques (p=0.005), with FAF detecting it earlier than SD-OCT. When RPE atrophy was found first on FAF, the median time to diagnosis with SD-OCT was 6.6 months (95% CI 5.5 to 8.6), while if detection occurred earlier on SD-OCT, the median time until identification with FAF was 12.6 months (95% CI 6.0 to 23.4; p=0.0003). Conclusions. In iAMD cases in which early atrophy overlying drusen is not detected simultaneously in FAF and SD-OCT, FAF was significantly more sensitive. Nevertheless, a multimodal approach is recommended and required to evaluate these patients.

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