Macular Choroidal Thickness and Volume in Normal Subjects Measured by Swept-Source Optical Coherence Tomography

2011 ◽  
Vol 52 (8) ◽  
pp. 4971 ◽  
Author(s):  
Masaya Hirata ◽  
Akitaka Tsujikawa ◽  
Akiko Matsumoto ◽  
Masanori Hangai ◽  
Sotaro Ooto ◽  
...  

2019 ◽  
Vol 4 (1) ◽  
pp. e000258 ◽  
Author(s):  
Swetha Komma ◽  
Jay Chhablani ◽  
Mohammed Hasnat Ali ◽  
Chandra S Garudadri ◽  
Sirisha Senthil

ObjectiveTo elucidate the difference between choroidal thickness (CT) in primary open-angle glaucoma (POAG) and normal subjects and to compare the CT measured using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT).Methods and analysisThis cross-sectional observational study included 25 eyes of 17 POAG subjects (cases) and 31 eyes of 20 normal subjects (controls). All the patients underwent complete ophthalmologic examination, enhanced depth imaging, SD-OCT and SS-OCT. In both controls and cases, the CT was measured in seven predetermined points in macular and peripapillary area and were compared.ResultsChoroid was significantly thicker on SS-OCT compared with SD-OCT in peripapillary and macular area in both cases and controls, except for inferior peripapillary in controls. The CT was not different from glaucoma and controls in peripapillary or macular area on SD-OCT (p>0.05), however, the CT was significantly thicker in glaucoma compared with controls in peripapillary area on SS-OCT (p<0.05) except inferior peripapillary (p=0.13). There was good intraobserver (±20 µm) and interobserver (±55 µm and ±45 µm) agreement on both SD-OCT and SS-OCT respectively.On SD-OCT, choroid was thinnest at the temporal peripapillary and thickest at subfoveal location in controls. In POAG, choroid was thinnest at inferior peripapillary region and thickest (500 µm) nasal to the fovea. On SS-OCT, choroid was thinnest at inferior peripapillary and thickest at the temporal peripapillary area in both cases and controls.ConclusionCT measurements on SS-OCT were higher than the SD-OCT measurements possibly due to better delineation of the sclerochoroidal junction on SS-OCT. CT was significantly thicker in glaucoma subjects compared with controls in peripapillary area on SS-OCT but not in macular area.



Author(s):  
Rosa Dolz-Marco ◽  
María Andreu-Fenoll ◽  
Pablo Hernández-Martínez ◽  
M. Dolores Pinazo-Durán ◽  
Roberto Gallego-Pinazo


PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e109683 ◽  
Author(s):  
Chunwei Zhang ◽  
Andrew J. Tatham ◽  
Felipe A. Medeiros ◽  
Linda M. Zangwill ◽  
Zhiyong Yang ◽  
...  


2021 ◽  
Vol 62 (3) ◽  
pp. 5
Author(s):  
Min-Su Kim ◽  
Hyung-Bin Lim ◽  
Woo-Hyuk Lee ◽  
Kyeung-Min Kim ◽  
Ki Yup Nam ◽  
...  




2020 ◽  
pp. 112067212091453 ◽  
Author(s):  
Raffaella Rosa ◽  
Paolo Corazza ◽  
Maria Musolino ◽  
Chiara Mochi ◽  
Guido Maiello ◽  
...  

Reticular pseudodrusen are associated with a thinner choroid. The aim of our study was to determine the differences in central choroidal thickness and choriocapillaris vascular flow area between eyes with and without reticular pseudodrusen using swept-source optical coherence tomography and swept-source optical coherence tomography angiography. We conducted a retrospective case control study which included 27 eyes from 27 consecutive patients with intermediate age-related macular degeneration and 17 eyes from 17 healthy participants. Complete ophthalmic examinations were carried out including axial length measurements; fundus color retinography; fundus autofluorescence; swept-source optical coherence tomography and swept-source optical coherence tomography angiography; central choroidal thickness and choriocapillaris vascular flow area. Patients were classified as no reticular pseudodrusen, mild reticular pseudodrusen, and severe reticular pseudodrusen. Mean central choroidal thickness in patients exhibiting severe reticular pseudodrusen (110 ± 56 μm) was significantly smaller than in patients with no reticular pseudodrusen (201 ± 76 μm, p < 0.01). Mean choriocapillaris vascular flow area in severe reticular pseudodrusen patients (45.2% ± 3.0%) was also significantly less than in patients with no (47.9% ± 1.6%, p < 0.001) and mild reticular pseudodrusen (47.7% ± 1.0%, p < 0.05). Stepwise multiple regression models confirmed the association of reticular pseudodrusen with central choroidal thickness (p < 0.001) and choriocapillaris vascular flow area (p < 0.01) even after accounting for age, axial length, and refractive error. Soft drusen were not associated with changes in either central choroidal thickness (p = 0.13) nor choriocapillaris vascular flow area (p = 0.29). A significant, positive relationship was found between central choroidal thickness and choriocapillaris vascular flow area (r = 0.44, p = 0.01). Therefore, both central choroidal thickness and choriocapillaris vascular flow area are decreased in eyes with reticular pseudodrusen, as compared to healthy eyes and intermediate age-related macular degeneration eyes not exhibiting reticular pseudodrusen. In addition, central choroidal thickness and choriocapillaris vascular flow area are related, and the reduction of either is directly associated to the severity of reticular pseudodrusen. Further studies are needed to assess the clinical significance of these findings.



2013 ◽  
Vol 91 ◽  
pp. 0-0
Author(s):  
JM RUIZ MORENO ◽  
J RUIZ-MEDRANO ◽  
I FLORES-MORENO ◽  
P PEñA-GARCíA ◽  
JA MONTERO


2016 ◽  
Vol 30 (1) ◽  
pp. 32 ◽  
Author(s):  
Jung Wook Lee ◽  
In Seok Song ◽  
Ju-hyang Lee ◽  
Yong Un Shin ◽  
Han Woong Lim ◽  
...  


2013 ◽  
Vol 54 (1) ◽  
pp. 353 ◽  
Author(s):  
José M. Ruiz-Moreno ◽  
Iñaki Flores-Moreno ◽  
Francisco Lugo ◽  
Jorge Ruiz-Medrano ◽  
Javier A. Montero ◽  
...  


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