scholarly journals Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

2019 ◽  
Vol 4 (1) ◽  
pp. e000258 ◽  
Author(s):  
Swetha Komma ◽  
Jay Chhablani ◽  
Mohammed Hasnat Ali ◽  
Chandra S Garudadri ◽  
Sirisha Senthil
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Normal Subjects ◽  
Optical Coherence ◽  
Macular Area ◽  
Swept Source ◽  
Sd Oct ◽  
Peripapillary Area

ObjectiveTo elucidate the difference between choroidal thickness (CT) in primary open-angle glaucoma (POAG) and normal subjects and to compare the CT measured using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT).Methods and analysisThis cross-sectional observational study included 25 eyes of 17 POAG subjects (cases) and 31 eyes of 20 normal subjects (controls). All the patients underwent complete ophthalmologic examination, enhanced depth imaging, SD-OCT and SS-OCT. In both controls and cases, the CT was measured in seven predetermined points in macular and peripapillary area and were compared.ResultsChoroid was significantly thicker on SS-OCT compared with SD-OCT in peripapillary and macular area in both cases and controls, except for inferior peripapillary in controls. The CT was not different from glaucoma and controls in peripapillary or macular area on SD-OCT (p>0.05), however, the CT was significantly thicker in glaucoma compared with controls in peripapillary area on SS-OCT (p<0.05) except inferior peripapillary (p=0.13). There was good intraobserver (±20 µm) and interobserver (±55 µm and ±45 µm) agreement on both SD-OCT and SS-OCT respectively.On SD-OCT, choroid was thinnest at the temporal peripapillary and thickest at subfoveal location in controls. In POAG, choroid was thinnest at inferior peripapillary region and thickest (500 µm) nasal to the fovea. On SS-OCT, choroid was thinnest at inferior peripapillary and thickest at the temporal peripapillary area in both cases and controls.ConclusionCT measurements on SS-OCT were higher than the SD-OCT measurements possibly due to better delineation of the sclerochoroidal junction on SS-OCT. CT was significantly thicker in glaucoma subjects compared with controls in peripapillary area on SS-OCT but not in macular area.

Ciliary muscle dimensions measured by swept-source optical coherence tomography in eyes with primary open-angle glaucoma and healthy eyes

2020 ◽  
Vol 40 (9) ◽  
pp. 2247-2255
Author(s):  
Bachar Kudsieh ◽  
José Ignacio Fernández-Vigo ◽  
Hang Shi ◽  
Lucía De Pablo Gómez de Liaño ◽  
José María Ruiz-Moreno ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Ciliary Muscle ◽  
Optical Coherence ◽  
Open Angle ◽  
Swept Source ◽  
Healthy Eyes

Macular Choroidal Thickness and Volume in Normal Subjects Measured by Swept-Source Optical Coherence Tomography

2011 ◽  
Vol 52 (8) ◽  
pp. 4971 ◽  
Author(s):  
Masaya Hirata ◽  
Akitaka Tsujikawa ◽  
Akiko Matsumoto ◽  
Masanori Hangai ◽  
Sotaro Ooto ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Normal Subjects ◽  
Optical Coherence ◽  
Swept Source

scholarly journals Comparison of Choroidal Thickness Measurements between Spectral-domain Optical Coherence Tomography and Swept-source Optical Coherence Tomography in Children

2021 ◽  
Author(s):  
Chun On Lee ◽  
Xiujuan Zhang ◽  
Shumin Tang ◽  
Li Jia Chen ◽  
Carol Cheung ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Correlation Coefficient ◽  
Choroidal Thickness ◽  
Relative Difference ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Normal Children ◽  
Swept Source ◽  
Thickness Measurements ◽  
Sd Oct

Abstract PURPOSE: Choroidal thickness is associated with many ocular conditions, interchangeability among different generations of optical coherence tomography is therefore important for both research purpose and clinical application. Hence, we compared choroidal thickness measurements between spectral-domain optical coherence tomography (SD-OCT) and swept-source optical coherence tomography (SS-OCT) in healthy pediatric eyes.METHODS: Children from the population–based Hong Kong Children Eye Study were recruited. Choroidal thickness was measured by both devices. Intra-class correlation coefficient (ICC) was used to compare the measurements.RESULTS: A total of 114 children with mean age of 7.38±0.82 years were included. The central foveal choroidal thickness (CFCT) measured by SD-OCT and SS-OCT was 273.24±54.29μm and 251.84±47.12μm respectively. Inter-device correlation coefficient was 0.840 (95%CI: 0.616-0.918). However, choroidal thickness obtained by SD-OCT was significantly thicker than that measured by SS-OCT with a mean difference of 21.40±33.13μm (P<0.001). Bland-Altman limit of agreement on the relative difference scale for SD-OCT/SS-OCT was 86.33μm. Validated conversion equation for translating SD-OCT CFCT measurement into SS-OCT was SS-OCT = 35.261 + 0.810 x SD-OCT. CONCLUSIONS: ICC shows an acceptable agreement between SD-OCT and SS-OCT, however, there was a significant inter-device difference of choroidal thickness measurements in normal children eyes. Therefore, the measurements are not interchangeable.

scholarly journals Effects of myopia and glaucoma in the prelaminar neural canal and anterior lamina cribrosa using 1060-nm swept-source OCT

2021 ◽  
Author(s):  
Sieun Lee ◽  
Morgan Heisler ◽  
Dhanashree Ratra ◽  
Vineet Ratra ◽  
Paul J Mackenzie ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Field ◽  
Optic Disc ◽  
Open Angle Glaucoma ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Inclusion Criteria ◽  
Swept Source ◽  
Neural Canal ◽  
Sd Oct

Purpose: Investigate the effects of myopia and glaucoma in the prelaminar neural canal and anterior lamina cribrosa using 1060-nm swept-source optical coherence tomography Design: Retrospective, cross-sectional study Methods: - Setting: Clinical practice - Patient or study population: 19 controls (38 eyes); 38 glaucomatous subjects (63 eyes). Inclusion criteria for glaucomatous subjects: i) optic disc neural rim loss; ii) peripapillary nerve fibre layer (NFL) loss on spectral domain optical coherence tomography (SD-OCT); iii) glaucomatous visual field defect with an abnormal pattern standard deviation (P<.05); iv) stable SD-OCT, visual field, and optic disc clinical examination for 6 or more months. Inclusion criteria for control subjects: no evidence of retinal or optic nerve pathology. Exclusion criteria: i) retinal diseases or optic neuropathy other than primary open-angle glaucoma; ii) intraocular pressure ≤ 10 mmHg or ≥ 20 mmHg; iii) ocular media opacities; iv) any surgery-related complication deemed inappropriate for the study. - Intervention or observation procedures: Swept-source optical coherence tomography - Main Outcome Measure(s): Bruchs membrane opening (BMO) and anterior laminar insertion (ALI) dimension, prelaminar neural canal dimension, anterior lamina cribrosa surface (ALCS) depth Results: Glaucomatous eyes had more bowed and nasally rotated BMO and ALI, more horizontally skewed prelaminar neural canal, and deeper ALCS than the control eyes. Increased axial length was associated with a wider, longer, and more horizontally skewed neural canal, and decrease in the ALCS depth and curvature. Conclusion: Our findings suggest that glaucomatous posterior bowing or cupping of lamina cribrosa can be significantly confounded by the myopic expansion of the neural canal. This may be related to higher glaucoma risk associated with myopia from decreased compliance and increased susceptibility to IOP-related damage of LC being pulled taut.

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