Minocycline in the Antibiotic Regimen of Cystic Fibrosis Patients: Weight Gain and Clinical Improvement

1977 ◽  
Vol 16 (1) ◽  
pp. 60-63 ◽  
Author(s):  
Paul R. Patterson
PEDIATRICS ◽  
1961 ◽  
Vol 28 (3) ◽  
pp. 399-409
Author(s):  
John H. Menkes ◽  
George A. Jervis

An infant with seizures, spasticity, and failure in weight gain was shown to excrete p-hydroxyphenylpyruvic acid, p-hydroxyphenyllactic acid, and p-hydroxyphenylacetic acid, indicating the likelihood of an impairment in the oxidation of p-hydroxyphenylpyruvate. Institution of a phenylalanine-free diet coincided with marked clinical improvement and disappearance of the abnormal urinary metabolites. The cause of the temporary enzyme defect is discussed, and it is concluded that it represents a persistence into extrauterine life of the relative enzyme inactivity observed in fetal tissues.


Author(s):  
Jeremy Hull ◽  
Julian Forton ◽  
Anne H. Thompson

Author(s):  
Jeremy Hull ◽  
Julian Forton ◽  
Anne Thomson

2002 ◽  
Vol 140 (4) ◽  
pp. 439-444 ◽  
Author(s):  
Valerie Eubanks ◽  
Nicki Koppersmith ◽  
Nancy Wooldridge ◽  
J.P. Clancy ◽  
Raymond Lyrene ◽  
...  

2020 ◽  
Vol 90 (4) ◽  
Author(s):  
Maddalena Giglia ◽  
Giacomo Beci ◽  
Elena Rosselli Del Turco ◽  
Viola Guardigni ◽  
Alberto Amedeo ◽  
...  

We report the case of a man affected by cystic fibrosis who developed a severe SARS-CoV-2 related pneumonia in March 2020. In addition to lopinavir/ritonavir and hydroxychloroquine, he was treated with two doses of tocilizumab, displaying a significant clinical improvement. This is the first case described in the literature of an adult patient affected by cystic fibrosis who received tocilizumab for COVID-19, with documented total recovery, also assessed by a spirometry.


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