Necrotising Pancreatitis and Diabetes Associated with Disseminated Small Cell Carcinoma of Lung

Although tumour metastases to the pancreas and peripancreatic lymph nodes are found commonly at necropsy in cases of small cell carcinoma of lung, tumour-induced acute pancreatitis is described rarely. A case of metastasis-associated necrotising pancreatitis with the unusual presentation of epigastric pain followed by diabetes is described here. Patients (particularly cigarette smokers) with none of the conventional risk factors for acute pancreatitis merit chest radiography and if indicated prompt cytotoxic treatment.

Download Full-text

Metastatic Small Cell Carcinoma Presenting as Acute Pancreatitis

Cureus ◽

10.7759/cureus.8975 ◽

2020 ◽

Author(s):

Cameron Burmeister ◽

Tamer S Said Ahmed ◽

Mohammad Taleb

Keyword(s):

Acute Pancreatitis ◽

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Small Cell

Download Full-text

A CASE OF SMALL CELL CARCINOMA OF THE LUNG DIAGNOSED INITIALLY AS ACUTE PANCREATITIS

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) ◽

10.3919/jjsa.69.160 ◽

2008 ◽

Vol 69 (1) ◽

pp. 160-165 ◽

Cited By ~ 2

Author(s):

Hiromichi MIYAGAKI ◽

Shoji NAKAMORI ◽

Masaki KASHIWAZAKI ◽

Masakazu IKENAGA ◽

Toshimasa TSUJINAKA ◽

...

Keyword(s):

Acute Pancreatitis ◽

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Small Cell

Download Full-text

Gastric Small-Cell Carcinoma Found on Esophagogastroduodenoscopy: A Case Report and Literature Review

Case Reports in Oncological Medicine ◽

10.1155/2013/475961 ◽

2013 ◽

Vol 2013 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Natassja Frances ◽

Simon B. Zeichner ◽

Michael Francavilla ◽

Mike Cusnir

Keyword(s):

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Epigastric Pain ◽

Gastric Wall ◽

Rare Condition ◽

Small Cell ◽

Japanese Male ◽

History Of ◽

Lesser Curvature ◽

Hispanic Male

Introduction. Characterized as an undifferentiated, neuroendocrine tumor arising from totipotent stem cells, small-cell carcinoma (SCC) most commonly arises from the lung. Extrapulmonary small-cell carcinomas (ESCC) are rare and account for only four percent of SCC. Gastric ESCC, more commonly seen in Japanese male patients in their seventh decade of life, accounts for approximately 0.1 percent of ESCC.Case Presentation. A 75-year-old Hispanic male presented with a several week history of worsening epigastric pain with nausea and vomiting. Computer tomography (CT) of the abdomen and pelvis showed a large heterogeneous mass involving the posterior gastric wall with diffuse extension into the gastric cardia. Esophagogastroduodenoscopy (EGD) revealed a large fungating mass in the lesser curvature of the stomach. Biopsy of the mass revealed small-cell carcinoma of the stomach. The patient was diagnosed with extensive/stage 4 disease and started on chemoradiation.Discussion. Our case, of a very rare condition highlights, the importance of recognizing atypical pathologic diagnoses. More research will need to be conducted with GSCC patients in order to better characterize disease pathogenesis, genetic mutations, and optimal disease management. The hope is to identify biomarkers that will identify patients earlier in their disease course when cure is possible.

Download Full-text