scholarly journals Comparative Study Between the Auditory and Vestibular Functions in Ménière’s Disease

2020 ◽  
pp. 014556132096944
Author(s):  
Stefani Maihoub ◽  
András Molnár ◽  
Anita Gáborján ◽  
László Tamás ◽  
Ágnes Szirmai
Keyword(s):  
Pure Tone Audiometry ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Caloric Test ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Canal Paresis ◽  
Ménière's Disease ◽  
Interaural Difference

Objectives: To evaluate the relationship between the loss of the cochleovestibular functions in Ménière’s disease (MD). Methods: Forty-three patients with definite MD underwent pure-tone audiometry (PTA) and caloric test. Canal paresis (CP%), dPTA (interaural difference), and average PTA results were contrasted. IBM SPSS V24 was used for statistical analysis. Results: According to PTA, most patients were in stage C, and caloric weakness was found in 29 patients. Linear ( R 2 = 0.06) and nonlinear correlation tests (rho = 0.245, P = .113) between canal paresis (CP%) and dPTA showed no correlation, as well as between CP% and PTA analysis ( R 2 = 0.007, rho = 0.11, P = .481). As per the categorial analysis, no correlation was detected between the groups either (κ = 0.174, 95% CI: 0.0883 - 0.431). Based on the results of the analysis, it was concluded that a more advanced stage determined by audiometry does not indicate increasing values in the CP% parameter. Conclusions: Audiometric changes do not directly correspond with the vestibular ones; therefore, no specific correlation exists between them. Thus, for therapy planning and diagnosis, both tests are necessary.

The Caloric Test in Menière's Disease

1964 ◽  
Vol 58 (sup192) ◽  
pp. 168-170 ◽  
Author(s):  
L. B. W. Jongkees ◽  
A. J. Philipszoon
Keyword(s):  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Caloric Test ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease

scholarly journals Results in caloric test, vHIT and inner ear MRI in patients with Ménière's disease

2021 ◽  
Vol 124 (6) ◽  
pp. 930-931
Author(s):  
Koich Kitano ◽  
Tadashi Kitahara ◽  
Taeko Ito ◽  
Tomoyuki Shiozaki ◽  
Yoshiro Wada ◽  
...  
Keyword(s):  
Inner Ear ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Caloric Test ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease

scholarly journals MRI With Intratympanic Gadolinium: Comparison Between Otoneurological and Radiological Investigation in Menière's Disease

2021 ◽  
Vol 8 ◽  
Author(s):  
Giampiero Neri ◽  
Armando Tartaro ◽  
Letizia Neri
Keyword(s):  
Endolymphatic Hydrops ◽  
Pure Tone Audiometry ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Complete Agreement ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Vestibular Loss ◽  
Ménière's Disease

Objectives/hypothesis: To compare findings obtained using both magnetic resonance imaging plus intratympanic gadolinium and audiovestibular testing for Menière's disease.Study design: Retrospective cohort study.Methods: Patients with definite unilateral Menière's disease (n = 35) diagnosed according to 2015 Barany Criteria were included. Three-dimensional real inversion recovery (3D-real-IR) MRI was executed 24 h after intratympanic gadolinium injection to assess the presence and degree of endolymphatic hydrops. Pure tone audiometry, bithermal caloric test, head impulse test, ocular, and cervical VEMPs using air-conducted sound were performed to evaluate the level of hearing and vestibular loss. The results were compared to verify precision of the method in providing correct diagnoses.Results: Different degrees of endolymphatic hydrops were observed in the MRI of the cochlea and vestibule in the affected ears of Menière's disease patients, even though it was impossible to radiologically distinguish the two otolithic structures separately. The correlation between the degree of linked alterations between instrumental and MRI testing was statistically significant. In particular, an 83% correspondence with audiometry, a 63% correspondence for cVEMPs and 60% correspondence for cVEMPs were seen. While for HIT the accordance was 70 and 80% for caloric bithermal test.Conclusions: MRI using intratympanic gadolinium as a contrast medium has proved to be a reliable and harmless method, even though there is an objective difficulty in disclosing macular structures. The study revealed that there is no complete agreement between instrumental values and MRI due to the definition of the image and fluctuation of symptoms. The present work highlights the greater (but not absolute) sensitivity of otoneurological tests while MRI, although not yet essential for diagnosis, is certainly important for understanding the disease and its pathogenic mechanisms.

VEMPs and dynamic posturography after intratympanic gentamycin in Menière's disease

2005 ◽  
Vol 15 (3) ◽  
pp. 161-168 ◽  
Author(s):  
Pasqualina M. Picciotti ◽  
Antonella Fiorita ◽  
Walter Di Nardo ◽  
Nicola Quaranta ◽  
Gaetano Paludetti ◽  
...  
Keyword(s):  
Postural Control ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Caloric Test ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Dynamic Posturography ◽  
Ménière's Disease

In this study, we investigated whether vestibular evoked myogenic potentials (VEMPs) and dynamic posturography (DP) are useful in the evaluation of the vestibular function in patients affected by active monoaural Menière's disease (MD) treated with intratympanic gentamycin. Twelve subjects affected by monoaural MD were treated with weekly intratympanic injections of 0.5 ml of gentamycin at a concentration of 20 mg/ml. VEMPs were used to test saccular function, while postural control was analyzed by DP. The results obtained with these two techniques were compared with those obtained by using bithermal caloric test. The mean follow-up was 15.3 months (6–28 months). Therapy resulted in complete absence of the caloric response in six subjects (50) and in caloric test-induced asymmetry in the remaining individuals, ranging from 83 to 27. At follow-up, eleven patients (91.6%) were free of vertigo, while one patient had two vertigo spells 9 months after treatment. Before treatment, VEMPs were present in the affected ear of eleven patients. After treatment VEMPs were absent in all the patients. At the end of follow-up, reappearance of VEMPs was observed in two patients, with no changes in latency values and amplitude ratio. DP demonstrated a reduction of the Composite Score (CS) one week after therapy, with a prevalent reduction of the vestibular component. After 6 months, there was an improvement of the CS and, in particular, of the vestibular component. The present study demonstrates that bithermal caloric test and VEMPs allow for the functional evaluation of both the horizontal semicircular canal and the sacculus, suggesting that these techniques might be used together to monitor the efficacy of intratympanic gentamycin therapy. In addition, our data indicate that DP might provide important information on compensation phenomena and show that intratympanic gentamycin can improve postural control in MD patients.

S233 – Diagnostic Role of Electrocochleography after Glycerol Test

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P153-P153
Author(s):  
Mohammadreza Majidi ◽  
Mokhtari Nematollah ◽  
Tale Mohammadreza ◽  
Rauf Aliasghar ◽  
Mohammad Taghi Shakeri
Keyword(s):  
Pure Tone ◽  
Endolymphatic Hydrops ◽  
Pure Tone Audiometry ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Glycerol Test

Objectives Response to dehydrating agents such as glycerol in Meniere's disease is evaluated by audiometric shifts after substance administration. Since the major pathogenic event in this disease is endolymphatic hydrops, evidenced by elevated SP/AP ratio, this study was conducted to determine the value of electrochochleography in assessment of response to glycerol administration in patients with definite Meniere's disease. Methods Between October 2006 and December 2007, 12 women and 10 men with definite Meniere's disease, based on AAO-HNS guidelines during acute phase, were included in this study. Pure tone audiometry (before and 1,2,3 hours after glycerol administration) and extratympanic electrocochleography (before and 3 hours after test) were performed; improvement in tinnitus, aural fullness, and vertigo symptoms were recorded after glycerol administration. Chi-square test was used to compare the sensitivity of electrocochleography and pure tone audiometry for detection of response to glycerol test. Results 22 patients, mean age of 40.18±8.8 years, were included in this study. Of 16 patients with tinnitus complaint, 9 patients reported significant improvement after glycerol test. Of 22 patients with vertigo and aural fullness symptoms, 19 reported significant clinical improvement. The SP/AP ratio was significantly reduced and reached to less than 80% of pretest values in 17 of these patients, but improvement in pure tone thresholds was observed in 8 patients. The difference between 2 methods was significant (p<0.05). Conclusions It seems that significant reduction in SP/AP ratio in patients with Meniere's disease might be a more sensitive indicator of the response to glycerol test than pure tone threshold shifts.

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