Stability of Characters of Mammary Tumors in Balb/cfRIII Mice

1980 ◽  
Vol 66 (4) ◽  
pp. 439-444 ◽  
Author(s):  
Raffaele Pingitore

The biological and morphological characteristics of mammary tumors in BALB/c mice infected with RIII mammary tumor virus (MTV) by foster nursing have substantially kept stable and unchanged after 20 years, 53 inbred generations and transfer of the strain from Perugia to Pisa. This suggests that the causal MTV keeps unaltered in time its biological properties.

Author(s):  
T. Kodama ◽  
W. C. Williams ◽  
R. L. Hales ◽  
L. Dmochowski

Morphological, biological, and immunological studies indicate a possible interrelationship between mouse mammary tumor virus and leukemia virus in the development of mouse mammary tumors. Electron microscope studies have shown the presence of both mouse mammary tumor virus (type B) particles and mouse leukemia virus (type C) particles in mouse milk, in tissues, and in tissue cultures from spontaneous and induced mouse mammary tumors (Dmochowski, L., et; al.: Carcinogenesis, A Broad Critique, Williams and Wilkins Co., Baltimore, p.211, 1967;., Dmochowski, L., et al.: J.Nat. Cancer Inst., 40:1339, 1968).


Sign in / Sign up

Export Citation Format

Share Document