VATS Thymectomy for Nonthymomatous Myasthenia Gravis Standardized Outcome Assessment Using the Myasthenia Gravis Foundation of America Clinical Classification

Author(s):  
Cameron P. Keating ◽  
Yu X. Kong ◽  
Valerie Tay ◽  
Simon R. Knight ◽  
C. Peter Clarke ◽  
...  
Author(s):  
Cameron P. Keating ◽  
Yu X. Kong ◽  
Valerie Tay ◽  
Simon R. Knight ◽  
C. Peter Clarke ◽  
...  

Objective Video-assisted thoracoscopic (VATS) thymectomy has been practiced in Australia for nearly two decades. Our aim was to assess the complete stable remission and asymptomatic disease rates after VATS thymectomy in nonthymomatous myasthenia gravis. There remains doubt that minimally invasive techniques achieve equal remission rates to open maximal operations. Therefore, we report our outcomes using the Myasthenia Gravis Foundation of America (MGFA) Clinical Classification and Kaplan-Meier analysis and compare the results to the literature. Methods A retrospective analysis of 78 consecutive patients undergoing right VATS thymectomy between April 1994 and March 2007 at two Thoracic Surgery Units in Melbourne, Australia, was undertaken. Patients with thymoma were excluded. Therefore, 57 patients were followed-up for a minimum of 12 months to apply the MGFA Clinical Classification. VATS thymectomy was performed by a three-port right side technique. Results The complete stable remission rate was 15% at 3 years and 28% at 5 years. The asymptomatic disease rate was 59% at 5 years. Median follow-up was 32 months. No prognostic factors for remission were identified. The overall morbidity rate was 14% (8/57). Conclusions Right VATS thymectomy achieves comparable remission and asymptomatic disease rates to other minimally invasive and open techniques when compared with studies using either MGFA or older criteria.


2000 ◽  
Vol 9 (3) ◽  
pp. A185
Author(s):  
Gavin M. Wright ◽  
Stephen Barnett ◽  
C.Peter Clarke

2014 ◽  
Vol 48-49 ◽  
pp. 143-148 ◽  
Author(s):  
Sonia Berrih-Aknin ◽  
Mélinée Frenkian-Cuvelier ◽  
Bruno Eymard

2021 ◽  
Vol 56 (2) ◽  
pp. 165-171
Author(s):  
Tho Kieu Anh PHAM ◽  
◽  
Van De TRAN ◽  
Kien Trung NGUYEN ◽  
Phuong Van PHAM ◽  
...  

2017 ◽  
Vol 2 ◽  
pp. 12-12 ◽  
Author(s):  
Bianca Bromberger ◽  
Joshua Sonett

2007 ◽  
Vol 16 ◽  
pp. S18-S19
Author(s):  
C. Keating ◽  
Y. Kong ◽  
V. Tay ◽  
S. Knight ◽  
C.P. Clarke ◽  
...  

2021 ◽  
Vol 39 (2 Suppl) ◽  
pp. 87-92
Author(s):  
Seung Woo Kim ◽  
Ha Young Shin

The variable predominance of the affected muscle groups and the fluctuating severity and extent of myasthenia gravis (MG) makes it difficult to assess and classify these patients. With new treatments being developed and applied, it has become more important to properly classify MG patients and objectively evaluate the results of treatment. So far, a number of clinical classification and assessment systems have been proposed and used individually. However, for the comparative analysis, a uniform set of classifications and reliable measurement methods of muscle impairment are necessary. In this article, MG-clinical classification and several MG-specific assessment tools that are widely used are mentioned.


2011 ◽  
Vol 27 (6) ◽  
pp. 595-598 ◽  
Author(s):  
Ketan Parikh ◽  
Amrish Vaidya ◽  
Rajesh Jain

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