Pediatric hospital proximity to endovascular thrombectomy centers in the United States

2021 ◽  
pp. 159101992110593
Author(s):  
Cathy Y Yu ◽  
Kristin P Guilliams ◽  
Peter D Panagos ◽  
Akash P Kansagra
2020 ◽  
Vol 30 (2) ◽  
pp. 749-765
Author(s):  
Ashlie S. Tseng ◽  
H. Barrett Fromme ◽  
Jennifer Maniscalco ◽  
Karen E. Jerardi ◽  
Kelly S. Lockeman ◽  
...  

Radiology ◽  
2021 ◽  
Vol 299 (1) ◽  
pp. 179-189
Author(s):  
Pedram Golnari ◽  
Pouya Nazari ◽  
Sameer A. Ansari ◽  
Michael C. Hurley ◽  
Ali Shaibani ◽  
...  

2021 ◽  
pp. 112972982110119
Author(s):  
Ittikorn Spanuchart ◽  
Bakhtiar Amin ◽  
Adrian Sequeira ◽  
Chiranjiv Virk ◽  
Kenneth Abreo ◽  
...  

Arteriovenous fistula (AVF) thrombosis occurs less often when compared to arteriovenous grafts. Since the number of AVFs has increased in the United States, AVF thrombosis is seen more frequently today. AVF thrombectomy can be tedious, requires physician ingenuity, and many times results in failure. Substantial clot burden in megafistulas and aneurysms is considered a relative contraindication to endovascular thrombectomy. Usually, it results in surgical referral for open thrombectomy or, at times, abandonment of the fistula altogether. Herein, we describe the technique, results, and cautions of combining a continuous infusion of recombinant tissue plasminogen (rTPA) followed by angioplasty of the culprit stenotic lesion that was successful in opening five of six AVFs with a substantial clot burden.


Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Amrou Sarraj ◽  
James C Grotta ◽  
Sheryl Martin-Schild ◽  
Haris Kamal ◽  
Anjail Z Sharrief ◽  
...  

Background: Timely access to endovascular thrombectomy (EVT) centers is vital for best stroke outcome. We map current EVT access in the US then utilize modeling to optimize it. Methods: US designated stroke centers were mapped utilizing geo-mapping and stratified into EVT or non-EVT if they reported ≥1 thrombectomy code for acute ischemic stroke in 2017 to CMS. Direct EVT access, defined as the population with the closest facility to EVT centers, was calculated from validated trauma models adapted for stroke. Current 15 and 30 min access were described nationwide and in 4 states (TX, NY, CA, IL). Two optimization models were utilized. Model A used a greedy algorithm to capture the largest population with direct access when flipping 10 non-EVT to EVT centers to maximize access. Model B used bypassing methodology to directly transport patients to EVT centers within 15 min from the closest non-EVT center. Results: Of 1941 stroke centers, 714 were EVT. Approximately 99 million/32% Americans have direct EVT access within 15 min while 111 million (36.0%) within 30 minutes (Fig 1). There were 65 (43%) EVT centers in TX with 22% current 15 min access. Flipping the top 10 population density hospitals improved access to 32%, while bypassing resulted in 46% having direct access to EVT centers (fig 2 A-B). Direct access in CA was 26% which improved to 35% with flipping and 54% by 15 min bypassing from the closest non-EVT to EVT centers. Similar results were found in NY (current 21%, flipping 39%, bypassing 50%) and IL (15%, 27% and 35%, respectively), Tab 1. Conclusion: EVT access within 15 min is limited to less than 1/3 of the US population. Optimization methodology that increase EVT centers or bypass non-EVT to the closest EVT center both showed enhanced access. Results varied by states based on the population size and density. However, bypass showed more potential for maximizing direct EVT access. National and state efforts should focus on identifying gaps and tailoring solutions to improve EVT access.


Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Amrou Sarraj ◽  
Christine M Farrell ◽  
Katelin Reishus ◽  
Anjail Z Sharrief ◽  
Louise McCullough ◽  
...  

Stroke ◽  
2020 ◽  
Vol 51 (3) ◽  
pp. 899-907 ◽  
Author(s):  
Wolfgang G. Kunz ◽  
Mohammed A. Almekhlafi ◽  
Bijoy K. Menon ◽  
Jeffrey L. Saver ◽  
Myriam G. Hunink ◽  
...  

Background and Purpose— The benefit that endovascular thrombectomy offers to patients with stroke with large vessel occlusions depends strongly on reperfusion grade as defined by the expanded Thrombolysis in Cerebral Infarction (eTICI) scale. Our aim was to determine the lifetime health and cost consequences of the quality of reperfusion for patients, healthcare systems, and society. Methods— A Markov model estimated lifetime quality-adjusted life years (QALY) and lifetime costs of endovascular thrombectomy–treated patients with stroke based on eTICI grades. The analysis was performed over a lifetime horizon in a United States setting, adopting healthcare and societal perspectives. The reference case analysis was conducted for stroke at 65 years of age. National health and cost consequences of improved eTICI 2c/3 reperfusion rates were estimated. Input parameters were based on best available evidence. Results— Lifetime QALYs increased for every grade of improved reperfusion (median QALYs for eTICI 0/1: 2.62; eTICI 2a: 3.46; eTICI 2b: 5.42; eTICI 2c: 5.99; eTICI 3: 6.73). Achieving eTICI 3 over eTICI 2b reperfusion resulted on average in 1.31 incremental QALYs as well as healthcare and societal cost savings of $10 327 and $20 224 per patient. A 10% increase in the eTICI 2c/3 reperfusion rate of all annually endovascular thrombectomy–treated patients with stroke in the United States is estimated to yield additional 3656 QALYs and save $21.0 million and $36.8 million for the healthcare system and society, respectively. Conclusions— Improved reperfusion grants patients with stroke additional QALYs and leads to long-term cost savings. Procedural strategies to achieve complete reperfusion should be assessed for safety and feasibility, even when initial reperfusion seems to be adequate.


2020 ◽  
Vol 15 (7) ◽  
pp. 424-427 ◽  
Author(s):  
Kenneth B Roberts ◽  
Erin Ragan-Stucky Fisher ◽  
Daniel A Rauch

2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Pamela J. Gampetro ◽  
John P. Segvich ◽  
Neil Jordan ◽  
Barbara Velsor-Friedrich ◽  
Lisa Burkhart

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