Osmotic Demyelination Syndrome (Central Pontine and Extrapontine Myelinolysis with Coagulative Necrosis of the Putamina and Cortical Laminar Necrosis)

2008 ◽  
Vol 21 (4) ◽  
pp. 521-526 ◽  
Author(s):  
A. Burgetova ◽  
M. Vaneckova ◽  
Z. Seidl ◽  
O. Dolezal
1999 ◽  
Vol 41 (11) ◽  
pp. 835-839 ◽  
Author(s):  
S. Susa ◽  
M. Daimon ◽  
Y. Morita ◽  
M. Kitagawa ◽  
A. Hirata ◽  
...  

2018 ◽  
pp. bcr-2018-225751 ◽  
Author(s):  
Sanihah Abdul Halim ◽  
Nur Aida Mohd Amin

Osmotic demyelination syndrome commonly affects the pons and infrequently involves the extrapontine region. We report a patient with severe hyponatraemia who developed osmotic demyelination syndrome as a consequence of rapid sodium correction. The condition manifested as acute severe parkinsonism, bilateral ptosis and gaze impairment. MRI revealed typical features of central pontine and extrapontine myelinolysis. The patient improved gradually after treatment with a combination of levodopa, intravenous immunoglobulin and dexamethasone. However, it is important to emphasise that the improvement of neurological symptoms is not necessarily causal with these experimental therapies.


1996 ◽  
Vol 35 (5) ◽  
pp. 661
Author(s):  
Sai Ra Yoon ◽  
Jae Chan Shim ◽  
Ghi Jae Lee ◽  
Seong Wook Choi ◽  
Su Ok Seong ◽  
...  

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