Long-term follow-up on the use of vascularized fibular graft for the treatment of congenital pseudarthrosis of the tibia

Introduction: Vascularized fibular grafts (VFG) in the cervicothoracic spine have been used for patients with progressive neurofibromatosis (NF) type-1-related kyphosis, but the long-term outcomes of VFG with NF-1 are not well described. We describe the long-term follow-up of two cases of cervical kyphosis related to NF-1 treated with VFG in the cervical spine. Case Report: Case 1 was that of a 33-year-old man with a large neurofibroma at the back of his neck and an arteriovenous malformation at C2–7. The neurofibroma was resected by durotomy and intradural neurofibromas were extirpated through O-C6 laminectomy. Anterior fusion with VFG was performed 6 months later, and bone union was confirmed after 4 months. Cervical alignment was maintained with 50° kyphosis 15 years after the operation. The man suffered a subarachnoid hemorrhage 22 years after the operation. Case 2 was a 23-year-old woman with diastematomyelia at C6–T1 who was treated by anterior fusion with VFG at C4–T1. The diastematomyelia septum was resected through a C4–T1 laminectomy with simultaneous posterolateral fusion at C3–T2. Cervical alignment was maintained with 50° kyphosis 18 years later. The left vertebral artery ruptured and was embolized 10 years after the operation. Conclusion: Anterior fusion with VFG can achieve good bone union and maintains long-term alignment. However, it is important to watch for vascular events related to NF-1. Keywords: Vascularized fibular graft, cervical kyphosis, neurofibromatosis type 1.

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Successful total mandibular reconstruction using a fibular graft with long-term follow-up: A case report

Asian Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ajoms.2011.04.003 ◽

2011 ◽

Vol 23 (4) ◽

pp. 196-200 ◽

Cited By ~ 3

Author(s):

Takahiro Abe ◽

Hideaki Kitada ◽

Jun Sato ◽

Yutaka Yamazaki ◽

Ken-ichi Notani ◽

...

Keyword(s):

Case Report ◽

Mandibular Reconstruction ◽

Fibular Graft ◽

Long Term Follow Up

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Long-term Survival and Clinical Outcomes of Non-vascularized Autologous and Allogeneic Fibular Grafts are Comparable for Treating Osteonecrosis of the Femoral Head

10.21203/rs.3.rs-101438/v1 ◽

2020 ◽

Author(s):

Ke Jie ◽

Wenjun Feng ◽

Feilong Li ◽

Keliang Wu ◽

Jinlun Chen ◽

...

Keyword(s):

Survival Rate ◽

Femoral Head ◽

Clinical Outcomes ◽

Harris Hip Score ◽

Fibular Graft ◽

Vas Score ◽

Long Term Follow Up ◽

Group A

Abstract Background Osteonecrosis of the femoral head (ONFH) is a disabling disease, which often involves young patents. Recently, various hip-preserving surgeries were recommended to delay total hip arthroplasty (THA).Questions/purposes This study aimed to compare clinical outcomes and survival rate in the long-term follow-up between core decompression combined with a non-vascularized autologous fibular graft (group A) and an allogeneic fibular graft (group B) for the treatment of ONFH.Patients and Methods We retrospectively evaluated 117 patients (153 hips) with ONFH (Association Research Circulation Osseous [ARCO] stages IIa to IIIc) who underwent the above-mentioned hip-preserving surgeries between January 2003 and June 2012. The mean (range) follow-up times (years) were 12.9 (7–16) and 9.3 (6–16) in groups A and B, respectively. Clinical outcomes were assessed using the Harris hip score (HHS), visual analog scale (VAS) score, forgotten joint score (FJS). A survival analysis was performed using the Kaplan-Meier method. The end point was THA.Results Groups A and B showed postoperative improvements, respectively, in HHS from 65±7.2 to 80.3±14.5 and from 66±5.9 to 82.4±13.6 (p<0.05), and in VAS score from 6.3±1.1 to 2.3±1.6 and from 6.1±1 to 2.2±2.2 (p<0.05). However, no significant differences in the HHS, VAS score, and hip FJS at the last follow-up (p>0.05) and 15-year survival rate (84.1% and 86%, respectively, p>0.05) were found between group A and B.Conclusions Autologous and allogeneic fibular grafts can attain equally good clinical outcomes and high survival rates in long-term follow-up, and thus can greatly delay THA owing to good bone osseointegration and sufficient mechanical support. Notably, the ratio of failure will increase when patients were more than 37 years old.Level of Evidence Level III, therapeutic study.

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Long-term follow-up of fibular graft for the reconstruction of bone defects

Medicine ◽

10.1097/md.0000000000012605 ◽

2018 ◽

Vol 97 (40) ◽

pp. e12605 ◽

Cited By ~ 5

Author(s):

Siyi Liu ◽

Shengxiang Tao ◽

Jinhai Tan ◽

Xiang Hu ◽

Huiyi Liu ◽

...

Keyword(s):

Bone Defects ◽

Fibular Graft ◽

Long Term Follow Up ◽

Reconstruction Of Bone Defects

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Ilizarov bone transport as a treatment of congenital pseudarthrosis of the tibia: a long-term follow-up study

Journal of Children s Orthopaedics ◽

10.1007/s11832-015-0675-7 ◽

2015 ◽

Vol 9 (4) ◽

pp. 319-324 ◽

Cited By ~ 18

Author(s):

Jan Vanderstappen ◽

Johan Lammens ◽

Pieter Berger ◽

Armand Laumen

Keyword(s):

Bone Transport ◽

Follow Up Study ◽

Congenital Pseudarthrosis ◽

Long Term Follow Up ◽

Ilizarov Bone Transport

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Long-term survival and clinical outcomes of non-vascularized autologous and allogeneic fibular grafts are comparable for treating osteonecrosis of the femoral head

Journal of Orthopaedic Surgery and Research ◽

10.1186/s13018-021-02246-3 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Ke Jie ◽

Wenjun Feng ◽

Feilong Li ◽

Keliang Wu ◽

Jinlun Chen ◽

...

Keyword(s):

Survival Rate ◽

Femoral Head ◽

Clinical Outcomes ◽

Harris Hip Score ◽

Fibular Graft ◽

Term Survival ◽

Vas Score ◽

Long Term Follow Up

Abstract Background Osteonecrosis of the femoral head (ONFH) is a disabling disease, which often involves young patients. Recently, various hip-preserving surgeries were recommended to delay total hip arthroplasty (THA). Questions/purposes This study aimed to compare clinical outcomes and survival rate in the long-term follow-up between core decompression combined with a non-vascularized autologous fibular graft (group A) and an allogeneic fibular graft (group B) for the treatment of ONFH. Patients and methods We retrospectively evaluated 117 patients (153 hips) with ONFH (Association Research Circulation Osseous [ARCO] stages IIa to IIIc) who underwent the abovementioned hip-preserving surgeries between January 2003 and June 2012. The mean (range) follow-up times (years) were 12.9 (7–16) and 9.3 (6–16) in groups A and B, respectively. Clinical outcomes were assessed using the Harris Hip Score (HHS), visual analog scale (VAS) score, and forgotten joint score (FJS). A survival analysis was performed using the Kaplan-Meier method. The end point was THA. Results Groups A and B showed postoperative improvements, respectively, in HHS from 65 ± 7.2 to 80.3 ± 14.5 and from 66 ± 5.9 to 82.4 ± 13.6 (p < 0.05), and in VAS score from 6.3 ± 1.1 to 2.3 ± 1.6 and from 6.1 ± 1 to 2.2 ± 2.2 (p < 0.05). However, no significant differences in the HHS, VAS score, and hip FJS at the last follow-up (p > 0.05) and 15-year survival rate (84.1% and 86%, respectively, p > 0.05) were found between groups A and B. Conclusions Autologous and allogeneic fibular grafts can attain equally good clinical outcomes and high survival rates in long-term follow-up, and thus can greatly delay THA owing to good bone osseointegration and sufficient mechanical support. Notably, the ratio of failure will increase when patients were more than 37 years old. Level of evidence Level III, therapeutic study

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Congenital pseudarthrosis of both forearm bones: Long-term results of two cases managed by free vascularized fibular graft

The Journal Of Hand Surgery ◽

10.1053/jhsu.1999.0604 ◽

1999 ◽

Vol 24 (3) ◽

pp. 604-608 ◽

Cited By ~ 14

Author(s):

Yves Allieu ◽

Gero Meyer zu Reckendorf ◽

Michel Chammas ◽

Robert Gomis

Keyword(s):

Long Term Results ◽

Fibular Graft ◽

Vascularized Fibular Graft ◽

Congenital Pseudarthrosis ◽

Forearm Bones ◽

Free Vascularized Fibular Graft

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Long-term survival and clinical outcomes of non-vascularized autologous and allogeneic fibular grafts are comparable for treating osteonecrosis of the femoral head

10.21203/rs.3.rs-101438/v2 ◽

2021 ◽

Author(s):

Ke Jie ◽

Wenjun Feng ◽

Feilong Li ◽

Keliang Wu ◽

Jinlun Chen ◽

...

Keyword(s):

Survival Rate ◽

Femoral Head ◽

Clinical Outcomes ◽

Harris Hip Score ◽

Fibular Graft ◽

Vas Score ◽

Long Term Follow Up ◽

Group A

Abstract Background Osteonecrosis of the femoral head (ONFH) is a disabling disease, which often involves young patents. Recently, various hip-preserving surgeries were recommended to delay total hip arthroplasty (THA). Questions/purposes This study aimed to compare clinical outcomes and survival rate in the long-term follow-up between core decompression combined with a non-vascularized autologous fibular graft (group A) and an allogeneic fibular graft (group B) for the treatment of ONFH.Patients and Methods We retrospectively evaluated 117 patients (153 hips) with ONFH (Association Research Circulation Osseous [ARCO] stages IIa to IIIc) who underwent the above-mentioned hip-preserving surgeries between January 2003 and June 2012. The mean (range) follow-up times (years) were 12.9 (7–16) and 9.3 (6–16) in groups A and B, respectively. Clinical outcomes were assessed using the Harris hip score (HHS), visual analog scale (VAS) score, forgotten joint score (FJS). A survival analysis was performed using the Kaplan-Meier method. The end point was THA.Results Groups A and B showed postoperative improvements, respectively, in HHS from 65±7.2 to 80.3±14.5 and from 66±5.9 to 82.4±13.6 (p<0.05), and in VAS score from 6.3±1.1 to 2.3±1.6 and from 6.1±1 to 2.2±2.2 (p<0.05). However, no significant differences in the HHS, VAS score, and hip FJS at the last follow-up (p>0.05) and 15-year survival rate (84.1% and 86%, respectively, p>0.05) were found between group A and B.Conclusions Autologous and allogeneic fibular grafts can attain equally good clinical outcomes and high survival rates in long-term follow-up, and thus can greatly delay THA owing to good bone osseointegration and sufficient mechanical support. Notably, the ratio of failure will increase when patients were more than 37 years old.Level of Evidence Level III, therapeutic study.

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