scholarly journals Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children – common misconceptions revisited

2017 ◽  
Vol 10 ◽  
pp. 41 ◽  
Author(s):  
Ralf G. Heine ◽  
Fawaz AlRefaee ◽  
Prashant Bachina ◽  
Julie C. De Leon ◽  
Lanlan Geng ◽  
...  
1987 ◽  
Vol 22 (1) ◽  
pp. 99-99 ◽  
Author(s):  
P Juvonen ◽  
I Jakobsson ◽  
T Lindberg ◽  
L Lothe

1999 ◽  
Vol 134 (5) ◽  
pp. 614-622 ◽  
Author(s):  
Robert S. Zeiger ◽  
Hugh A. Sampson ◽  
S.Allan Bock ◽  
A.Wesley Burks ◽  
Kathleen Harden ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4230
Author(s):  
Elvira Verduci ◽  
Silvia Salvatore ◽  
Ilia Bresesti ◽  
Elisabetta Di Profio ◽  
Erica Pendezza ◽  
...  

Children with medical complexities, such as multi-system disorders and/or neurological impairments, often experience feeding difficulties and need enteral nutrition. They frequently have impaired motility and digestive–absorbing functions related to their underlying condition. If a cow’s milk allergy (CMA) occurs as a comorbidity, it is often misdiagnosed, due to the symptoms’ overlap. Many of the commercialized mixtures intended for enteral nutrition are composed of partially hydrolyzed cow’s milk proteins, which are not suitable for the treatment of CMA; thus, the exclusion of a concomitant CMA is mandatory in these patients for obtaining symptoms relief. In this review, we focus on the use of elemental and semi-elemental formulas in children with neurological diseases and in preterm infants as clinical “models” of medical complexity. In children with neurodisabilities, when gastrointestinal symptoms persist despite the use of specific enteral formula, or in cases of respiratory and/or dermatological symptoms, CMA should always be considered. If diagnosis is confirmed, only an extensively hydrolyzed or amino-acid based formula, or, as an alternative, extensively hydrolyzed nutritionally adequate formulas derived from rice or soy, should be used. Currently, enteral formulas tailored to the specific needs of preterm infants and children with neurological impairment presenting concomitant CMA have not been marketed yet. For the proper monitoring of the health status of patients with medical complexity, multidisciplinary evaluation and involvement of the nutritional team should be promoted.


2003 ◽  
Vol 70 (2) ◽  
pp. 175-179 ◽  
Author(s):  
Laura Paajanen ◽  
Tuula Tuure ◽  
Tuija Poussa ◽  
Riitta Korpela

It has been hypothesized that certain consumers tolerate untreated cow's milk, but react to processed (i.e. homogenized and pasteurized) cow's milk although they do not suffer from IgE-mediated cow's milk allergy or lactose intolerance. The aim of the study was to compare the tolerance of unhomogenized and homogenized cow's milk in lactose tolerant adults who had repeatedly experienced better tolerance of unhomogenized than homogenized milk. Forty-four subjects were challenged with homogenized and unhomogenized cow's milk for five days in a randomized, double-blind, cross-over study. No differences in the symptoms during the challenges were found. Roughly half the subjects tolerated the homogenized milk better and the other half tolerated the unhomogenized milk better. The results of this study show no difference in the tolerance of homogenized and unhomogenized milk in adults with self-reported symptoms suggestive of hypersensitivity to homogenized milk.


2021 ◽  
Vol 50 (4) ◽  
Author(s):  
Margherita Di Costanzo ◽  
Giacomo Biasucci ◽  
Ylenia Maddalena ◽  
Carmen Di Scala ◽  
Carmen De Caro ◽  
...  

2018 ◽  
Vol 73 (Suppl. 4) ◽  
pp. 30-37 ◽  
Author(s):  
Margherita Di Costanzo ◽  
Roberto Berni Canani

Lactose intolerance primarily refers to a syndrome having different symptoms upon the consumption of foods containing lactose. It is one of the most common form of food intolerance and occurs when lactase activity is reduced in the brush border of the small bowel mucosa. Individuals may be lactose intolerant to varying degrees, depending on the severity of these symptoms. When lactose is not digested, it can be fermented by gut microbiota leading to symptoms of lactose intolerance that include abdominal pain, bloating, flatulence, and diarrhea with a considerable intraindividual and interindividual variability in the severity of clinical manifestations. These gastrointestinal symptoms could be similar to cow’s milk allergy and could be wrongly labeled as symptoms of “milk allergy.” There are important differences between lactose intolerance and cow’s milk allergy; therefore, a better knowledge of these differences could limit misunderstandings in the diagnostic approach and in the management of these conditions.


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